Home General Interest Fabrication of ultra-sensitive carbon paste electrode with nanocomposite CdS modification for electroanalysis of rafoxanide in dosage form and biological fluids
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Fabrication of ultra-sensitive carbon paste electrode with nanocomposite CdS modification for electroanalysis of rafoxanide in dosage form and biological fluids

  • Waheed M. Salem , Mohamed A. Abdel-Lateef EMAIL logo , Mohamed A. Abdel Hamid and Hany A. Batakoushy
Published/Copyright: November 8, 2022
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Abstract

An anthelmintic, rafoxanide (RF), is frequently used in veterinary medicine to cure fascioliasis in cattle and sheep. A sensitive, quick, and selective detection of RF in its pharmaceutical preparation and in human urine was achieved through developing a new electrochemical sensor. The suggested method relied on the electro-oxidation of RF that used a modified carbon paste electrode in the presence of sodium dodecyl sulfate, which acts as an anionic surfactant. Voltammetric types were utilized in RF analysis, and these methods were cyclic voltammetry and differential pulse techniques. The suggested electro-analytical method’s validity is verified using the International Council on Harmonization (ICH/Q2) rules. The calibration curve for RF quantification was done in the concentration range from 2.9 × 10−6 to 3.1 × 10−4 M at cadmium sulfide modified carbon paste electrode. The limit of detection and the limit of quantification LOQ were found to be 6.7 × 10−7 M and 2.01 × 10−6 M, respectively. This study could be applied to the examined drug in QC-laboratory units, and also RF could be assayed in its pharmacokinetic studies.

Graphical abstract

Acknowledgments

The authors would like to thank National Research Center in Dokki, Egypt.

  1. Funding information: Authors state no funding involved.

  2. Author contributions: Waheed M. Salem: conceptualization, writing – original draft, visualization, methodology, investigation, and supervision; Mohamed A. Abdel-Lateef: writing – review; Mohamed A. Abdel Hamid and Hany A. Batakoushy: formal analysis, data curation, resources, writing – original draft, validation, and writing – review and editing.

  3. Conflict of interest: The authors state no conflict of interest.

  4. Precaution: Care must be taken when handling cadmium sulfide residues as they are toxic.

  5. Data availability statement: All data generated or analyzed during this study are included in this published article.

References

[1] Brayfield A. Martindale: the complete drug reference. Electronic version. London, UK: Pharmaceutical Press; 2013.Search in Google Scholar

[2] Barth T, Aleu J, Pupo MT, Bonato PS, Collado IG. HPLC analysis of midodrine and desglymidodrine in culture medium: Evaluation of static and shaken conditions on the biotransformation by fungi. J Chromatogr Sci. 2013;51(5):460–7.10.1093/chromsci/bms163Search in Google Scholar PubMed

[3] Benchaoui H, McKellar Q. Determination of rafoxanide and closantel in ovine plasma by high performance liquid chromatography. Biomed Chromatogr. 1993;7(4):181–3.10.1002/bmc.1130070402Search in Google Scholar PubMed

[4] Saad AS, Hamdy AM, Salama FM, Abdelkawy M. Validated UPLC and TLC-densitometry stability indicating methods for the determination of rafoxanide in the presence of its degradation products. J Chromatogr Sci. 2016;54(9):1661–9.10.1093/chromsci/bmw112Search in Google Scholar PubMed

[5] Sharma A, Ahmed A, Singh A, Oruganti SK, Khosla A, Arya S. Recent advances in tin oxide nanomaterials as electrochemical/chemiresistive sensors. J Electrochem Soc. 2021;168(2):027505.10.1149/1945-7111/abdee8Search in Google Scholar

[6] Swartz ME. UPLC™: An introduction and review. J Liq Chromatogr Rel Technol. 2005;28(7–8):1253–63.10.1081/JLC-200053046Search in Google Scholar

[7] Talley CP, Trenner NR, Downing GV, VandenHeuvel W. Gas chromatographic determination of rafoxanide [3′-chloro-4′-(4-chlorophenoxy)-3, 5-diiodosalicylanilide] in plasma by electron capture detection of its trimethylsilyl derivative. Anal Chem. 1971;43(11):1379–82.10.1021/ac60305a049Search in Google Scholar PubMed

[8] Yeung HS, Lee WO, Wong YT. Screening of closantel and rafoxanide in animal muscles by HPLC with fluorescence detection and confirmation using MS. J Sep Sci. 2010;33(2):206–11.10.1002/jssc.200900503Search in Google Scholar PubMed

[9] Fink DW. Spectrophotometric quantification of the salicylanilide anthelmintic rafoxanide based on the charge-transfer absorbance of its iron (III) complex. Anal Chim Acta. 1981;131:281–5.10.1016/S0003-2670(01)93561-5Search in Google Scholar

[10] Saad AS, Attia AK, Alaraki MS, Elzanfaly ES. Comparative study on the selectivity of various spectrophotometric techniques for the determination of binary mixture of fenbendazole and rafoxanide. Spectrochimica Acta Part A Mol Biomol Spectrosc. 2015;150:682–90.10.1016/j.saa.2015.05.098Search in Google Scholar PubMed

[11] Alharthi S, Batakoushy HA, Alharthy SA, El-Magied A, Mahmoud O, Salem WM. Electro-analytical sensing of anti-hypotensive agents: application to dosage forms and human urine. Toxicol Res. 2022;11(1):245–54.10.1093/toxres/tfac004Search in Google Scholar PubMed PubMed Central

[12] Radi A-E, El-Samboskany H. Anodic adsorptive stripping voltammetric determination of rafoxanide on glassy carbon electrode. Comb Chem High Throughput Screen. 2020;23(10):1002–9.10.2174/1386207323666200422083339Search in Google Scholar PubMed

[13] Alemu H, Khoabane NM, Tseki PF. Electrochemical oxidation of niclosamide at a glassy carbon electrode and its determination by voltammetry. Bull Chem Soc Ethiop. 2003;17(1).10.4314/bcse.v17i1.61740Search in Google Scholar

[14] Aziz MA, Kawde A-N. Gold nanoparticle-modified graphite pencil electrode for the high-sensitivity detection of hydrazine. Talanta. 2013;115:214–21.10.1016/j.talanta.2013.04.038Search in Google Scholar PubMed

[15] Kawde A-N, Aziz M, Baig N, Temerk Y. A facile fabrication of platinum nanoparticle-modified graphite pencil electrode for highly sensitive detection of hydrogen peroxide. J Electroanal Chem. 2015;740:68–74.10.1016/j.jelechem.2015.01.005Search in Google Scholar

[16] Kawde AN, Aziz MA. Disposable palladium nanoparticle-modified graphite pencil electrode. U.S. Patent No. 8,968,825; 2015.Search in Google Scholar

[17] Sağlam Ö, Dilgin DG, Ertek B, Dilgin Y. Differential pulse voltammetric determination of eugenol at a pencil graphite electrode. Mater Sci Eng C. 2016;60:156–62.10.1016/j.msec.2015.11.031Search in Google Scholar PubMed

[18] Wang J, Kawde A-N, Sahlin E. Renewable pencil electrodes for highly sensitive stripping potentiometric measurements of DNA and RNA. Analyst. 2000;125(1):5–7.10.1039/a907364gSearch in Google Scholar PubMed

[19] Dede E, Sağlam Ö, Dilgin Y. Sensitive voltammetric determination of niclosamide at a disposable pencil graphite electrode. Electrochim Acta. 2014;127:20–6.10.1016/j.electacta.2014.01.153Search in Google Scholar

[20] Alipour E, Majidi MR, Saadatirad A. mahdi Golabi S, Alizadeh AM. Simultaneous determination of dopamine and uric acid in biological samples on the pretreated pencil graphite electrode. Electrochim Acta. 2013;91:36–42.10.1016/j.electacta.2012.12.079Search in Google Scholar

[21] Barth T, Pupo MT, Borges KB, Okano LT, Bonato PS. Stereoselective determination of midodrine and desglymidodrine in culture medium: application to a biotransformation study employing endophytic fungi. Electrophoresis. 2010;31(9):1521–8.10.1002/elps.200900685Search in Google Scholar PubMed

[22] Dilgin Y, Ertek B, Kızılkaya B, Dilgin DG, Gökçel HI. Electrocatalytic oxidation of NADH using a pencil graphite electrode modified with hematoxylin. Sci Adv Mater. 2012;4(9):920–7.10.1166/sam.2012.1376Search in Google Scholar

[23] Dilgin Y, Kızılkaya B, Ertek B, Işık F, Dilgin DG. Electrocatalytic oxidation of sulphide using a pencil graphite electrode modified with hematoxylin. Sens Actuators B Chem. 2012;171:223–9.10.1016/j.snb.2012.03.020Search in Google Scholar

[24] Elzanfaly ES, Zaazaa HE, Merey HA. Ion selective phosphotungstate and β-cyclodextrin based membrane electrodes for stability-indicating determination of midodrine hydrochloride. Acta Chim Slovenica. 2013;60(2):256–62.Search in Google Scholar

[25] Furlanetto S, Pinzauti S, Gratteri P, La Porta E, Calzeroni G. Experimental design strategies in the optimization and robustness testing of adsorptive stripping voltammetric conditions for kynurenic acid determination. J Pharm Biomed Anal. 1997;15(9–10):1585–94.10.1016/S0731-7085(96)02029-8Search in Google Scholar

[26] Pala BB, Vural T, Kuralay F, Çırak T, Bolat G, Abacı S, et al. Disposable pencil graphite electrode modified with peptide nanotubes for Vitamin B12 analysis. Appl Surf Sci. 2014;303:37–45.10.1016/j.apsusc.2014.02.039Search in Google Scholar

[27] Uygun ZO, Dilgin Y. A novel impedimetric sensor based on molecularly imprinted polypyrrole modified pencil graphite electrode for trace level determination of chlorpyrifos. Sens Actuators B Chem. 2013;188:78–84.10.1016/j.snb.2013.06.075Search in Google Scholar

[28] Xu S, Zhu Q, Xu S, Yuan M, Lin X, Lin W, et al. The phase behavior of n-ethylpyridinium tetrafluoroborate and sodium-based salts ATPS and its application in 2-chlorophenol extraction. Chin J Chem Eng. 2021;33:76–82.10.1016/j.cjche.2020.07.024Search in Google Scholar

[29] Shalaby A, Hassan WS, Hendawy HA, Ibrahim A. Electrochemical oxidation behavior of itraconazole at different electrodes and its anodic stripping determination in pharmaceuticals and biological fluids. J Electroanal Chem. 2016;763:51–62.10.1016/j.jelechem.2015.12.047Search in Google Scholar

[30] Hendawy HA, Youssif RM, Salama NN, Fayed AS, Salem MY. Challenge approach of an inexpensive electrochemical sensor for rapid selective determination of two Non‐classical β‐lactams in presence of different degradants and interference substances. Electroanalysis. 2017;29(12):2708–18.10.1002/elan.201700431Search in Google Scholar

[31] Al‐Ghamdi AH, Al‐Ghamdi AF, Al‐Omar MA. Electrochemical studies and square‐wave adsorptive stripping voltammetry of spironolactone drug. Anal Lett. 2008;41(1):90–103.10.1080/00032710701746832Search in Google Scholar

[32] Rizk M, Hendawy HA, El‐Alamin MMA, Moawad MI. Sensitive anodic voltammetric determination of methylergometrine maleate in bulk and pharmaceutical dosage forms using differential pulse voltammetry. J Electroanal Chem. 2015;749:53–61.10.1016/j.jelechem.2015.04.029Search in Google Scholar

[33] Gosser DK. Cyclic voltammetry: simulation and analysis of reaction mechanisms. New York: VCH; 1993.Search in Google Scholar

[34] Guideline IHT. Validation of analytical procedures: text and methodology. Q2 (R1). 2005;1(20):5.Search in Google Scholar

[35] Abdel-Lateef MA, Alzahrani E, Pashameah RA, Almahri A, Abu-Hassan AA, El Hamd MA, et al. A specific turn-on fluorescence probe for determination of nitazoxanide based on feasible oxidation reaction with hypochlorite: Applying cobalt ferrite nanoparticles for pre-concentration and extraction of its metabolite from real urine samples. J Pharm Biomed Anal. 2022;219:114941.10.1016/j.jpba.2022.114941Search in Google Scholar PubMed

[36] Abdel-Lateef MA. Utilization of the peroxidase-like activity of silver nanoparticles nanozyme on O-phenylenediamine/H2O2 system for fluorescence detection of mercury (II) ions. Sci Rep. 2022;12(1):1–9.10.1038/s41598-022-10779-8Search in Google Scholar PubMed PubMed Central

[37] Miller JN, Miller JC. Statistics and chemometrics for analytical chemistry. 6th edn. Canada: Pearson Education; 2005.Search in Google Scholar

Received: 2022-07-22
Revised: 2022-09-17
Accepted: 2022-09-21
Published Online: 2022-11-08

© 2022 Waheed M. Salem et al., published by De Gruyter

This work is licensed under the Creative Commons Attribution 4.0 International License.

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