Startseite Production, separation and supply prospects of 67Cu with the development of fast neutron sources and photonuclear technology
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Production, separation and supply prospects of 67Cu with the development of fast neutron sources and photonuclear technology

  • Arjun Gopalakrishna , Saraswatula Venkata Suryanarayana , Haladhara Naik EMAIL logo , Tanuja Sushant Dixit , Basant Kumar Nayak , Amit Kumar , Pravind Maletha , Kiran Thakur , Abhay Deshpande , Ramamoorthy Krishnan , Kamaldeep , Sharmila Banerjee und Alok Saxena
Veröffentlicht/Copyright: 12. Februar 2018
Radiochimica Acta
Aus der Zeitschrift Radiochimica Acta Band 106 Heft 7

Abstract

Experimental investigations have been carried out on the production of a promising therapeutic radionuclide 67Cu via the 67Zn(n,p)67Cu, 68Zn(n,x)67Cu, and 68Zn(γ,p)67Cu reaction routes. Natural zinc metal foils were irradiated with 14.1 MeV neutrons and bremsstrahlung of end-point energy 15 MeV. Radioactivity levels of 67Cu and other radioisotopes co-produced were determined by the quantification of photo-peaks by off-line γ-ray spectrometry. No carrier added 67Cu was separated from the irradiated zinc by solvent extraction. Yields >90% and high levels of radionuclidic purity were achieved. These studies indicate that the growth and development of intense fast neutron sources and photonuclear technology, will possibly aid in the sustained supply of 67Cu.

Keywords: Cu-67; medical radionuclide; accelerator neutrons; 67Zn(n,p)67Cu; 68Zn(n,x)67Cu; 68Zn(γ,p)67Cu reactions; radiochemical separation; off-line γ-ray spectrometry

Acknowledgement

The authors thank Ms A. Chanda, Board of Radiation and Isotope Technology, and Ms S. Bishnoi and Mr T. Patel of Purnima Neutron Generator Facility and the operating staff of the electron LINAC at SAMEER for their help and assistance. The colleagues at Radiation Medicine Centre are acknowledged for technical support.

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Received: 2017-7-7
Accepted: 2018-1-18
Published Online: 2018-2-12
Published in Print: 2018-7-26

©2018 Walter de Gruyter GmbH, Berlin/Boston

Artikel in diesem Heft

  1. Frontmatter
  2. Production, isolation and characterization of radiochemically pure 163Ho samples for the ECHo-project
  3. Production, separation and supply prospects of 67Cu with the development of fast neutron sources and photonuclear technology
  4. Retardation of hexavalent uranium in muscovite environment: a batch study
  5. Zinc oxide impregnated resin for preconcentration and spectrophotometric determination of uranyl ions in aqueous solutions
  6. Efficient uptake of perrhenate/pertechnenate from aqueous solutions by the bifunctional anion-exchange resin
  7. Effect of water chemistry on Eu(III) biosorption by magnetic bioadsorbent
  8. 99mTc-HYNIC-(Ser)3-LTVPWY peptide bearing tricine as co-ligand for targeting and imaging of HER2 overexpression tumor
  9. Radiometric measurement of lignite coal and its by-products and assessment of the usability of fly ash as raw materials in Turkey
  10. Letter to the Editor
  11. International Consensus Radiochemistry Nomenclature Guidelines
https://doi.org/10.1515/ract-2017-2847
Schlagwörter für diesen Artikel
Cu-67; medical radionuclide; accelerator neutrons; 67Zn(n,p)67Cu; 68Zn(n,x)67Cu; 68Zn(γ,p)67Cu reactions; radiochemical separation; off-line γ-ray spectrometry

Artikel in diesem Heft

  1. Frontmatter
  2. Production, isolation and characterization of radiochemically pure 163Ho samples for the ECHo-project
  3. Production, separation and supply prospects of 67Cu with the development of fast neutron sources and photonuclear technology
  4. Retardation of hexavalent uranium in muscovite environment: a batch study
  5. Zinc oxide impregnated resin for preconcentration and spectrophotometric determination of uranyl ions in aqueous solutions
  6. Efficient uptake of perrhenate/pertechnenate from aqueous solutions by the bifunctional anion-exchange resin
  7. Effect of water chemistry on Eu(III) biosorption by magnetic bioadsorbent
  8. 99mTc-HYNIC-(Ser)3-LTVPWY peptide bearing tricine as co-ligand for targeting and imaging of HER2 overexpression tumor
  9. Radiometric measurement of lignite coal and its by-products and assessment of the usability of fly ash as raw materials in Turkey
  10. Letter to the Editor
  11. International Consensus Radiochemistry Nomenclature Guidelines
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