Preparation and characterization of iron(III) 99Mo-molybdate(VI) gels for the assessment of 99mTc elution performance

Mahmoud Amin; Tharwat W. Fasih; Mohamed A. El-Absy

doi:10.1515/ract-2017-2796

Article

Preparation and characterization of iron(III) ⁹⁹Mo-molybdate(VI) gels for the assessment of ^99mTc elution performance

Mahmoud Amin , Tharwat W. Fasih and Mohamed A. El-Absy

Published/Copyright: November 24, 2017

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From the journal Radiochimica Acta Volume 106 Issue 1

Abstract

New iron(III) ⁹⁹Mo-molybdate(VI) gels (Fe⁹⁹Mo) of high Mo content were prepared by the precipitation/filtration method. ⁹⁹Mo–MoO₃ dissolved in NaOH was added to aqueous solutions of Fe(NO₃)₃ at Mo/Fe mole fractions ~2.21 and 1.99 with continuous stirring at ambient room temperature. Two different Fe⁹⁹Mo were precipitated from the mixed solutions adjusted at pH 2 and 4.7. The amount of water of hydration increased with the increasing the gel settling time and pH of the mixed solution. The matrices were characterized by radiometric, XRD, SEM, XRF, FT-IR, TGA, and DTA measurements. Small chromatographic columns of 2.0 g Fe⁹⁹Mo containing ≥800 mg Mo tagged with 740 MBq ⁹⁹Mo were eluted with 5 mL saline solution. Highly reproducible ^99mTc elution indices suitable for preparation of ⁹⁹Mo/^99mTc generators were achieved from generator supported with 0.5 g Al₂O₃ filter. Elution performance of ^99mTc radionuclide was highly dependent on the gel structural properties.

Keywords: Iron(III) molybdate; matrix characterization; 99Mo/99mTc generator; elution behaviour of 99mTc

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Received: 2017-3-21

Accepted: 2017-6-22

Published Online: 2017-11-24

Published in Print: 2018-1-26

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Articles in the same Issue

https://doi.org/10.1515/ract-2017-2796

Keywords for this article

Iron(III) molybdate; matrix characterization; 99Mo/99mTc generator; elution behaviour of 99mTc