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Integration of chemo- and bio-catalysis to intensify bioprocesses

  • Yunting Liu EMAIL logo , Shiqi Gao , Pengbo Liu , Weixi Kong , Jianqiao Liu and Yanjun Jiang EMAIL logo
Published/Copyright: March 30, 2023
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Physical Sciences Reviews
From the journal Physical Sciences Reviews Volume 9 Issue 3

Abstract

Nature has evolved highly efficient and complex systems to perform cascade reactions by the elegant combination of desired enzymes, offering a strategy for achieving efficient bioprocess intensification. Chemoenzymatic cascade reactions (CECRs) merge the complementary strengths of chemo-catalysis and bio-catalysis, such as the wide reactivity of chemo-catalysts and the exquisite selective properties of biocatalysts, representing an important step toward emulating nature to construct artificial systems for achieving bioprocess intensification. However, the incompatibilities between the two catalytic disciplines make CECRs highly challenging. In recent years, great advances have been made to develop strategies for constructing CECRs. In this regard, this chapter introduces the general concepts and representative strategies, including temporal compartmentalization, spatial compartmentalization and chemo-bio nanoreactors. Particularly, we focus on what platform methods and technologies can be used, and how to implement these strategies. The future challenges and strategies in this burgeoning research area are also discussed.

Keywords: asymmetric synthesis; chemoenzymatic cascades; compartmentalization; co-immobilization; nanoreactor
Corresponding authors: Yunting Liu and Yanjun Jiang, School of Chemical Engineering and Technology, Hebei University of Technology, Tianjin 300130, China, E-mail: ,

Funding source: National Natural Science Foundation of China

Award Identifier / Grant number: 21901058

Award Identifier / Grant number: 22078081

Award Identifier / Grant number: 22178083

Funding source: National Key Research and Development Program of China

Award Identifier / Grant number: 2021YFC2104100

Funding source: Natural Science Foundation of Tianjin City

Award Identifier / Grant number: 20JCYBJC00530

Funding source: Hebei Key Research and Development Project

Award Identifier / Grant number: 20372802D

Award Identifier / Grant number: 21372804D

Award Identifier / Grant number: 21372805D

Funding source: Natural Science Foundation of Hebei Province

Award Identifier / Grant number: B2019202216

Funding source: Science and Technology Research Project of Hebei Higher Education

Award Identifier / Grant number: ZD2019045

  1. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Conflict of interest statement: The authors declare no conflicts of interest regarding this article.

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Received: 2022-07-12
Accepted: 2023-01-27
Published Online: 2023-03-30

© 2023 Walter de Gruyter GmbH, Berlin/Boston

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https://doi.org/10.1515/psr-2022-0103
Keywords for this article
asymmetric synthesis; chemoenzymatic cascades; compartmentalization; co-immobilization; nanoreactor

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  4. Development of nanocellulose fiber reinforced starch biopolymer composites: a review
  5. Recent developments in sago starch thermoplastic bio-composites
  6. Mechanical degradation of sugar palm crystalline nanocellulose reinforced thermoplastic sugar palm starch (TPS)/poly (lactic acid) (PLA) blend bionanocomposites in aqueous environments
  7. Computational design of the novel building blocks for the metal-organic frameworks based on the organic ligand protected Cu4 cluster
  8. Highly functional nanocellulose-reinforced thermoplastic starch-based nanocomposites
  9. Spectral peak areas do not vary according to spectral averaging scheme used in functional MRS experiments at 3 T with interleaved visual stimulation
  10. Triterpenoids of antibacterial extracts from the leaves of Bersama abyssinica Fresen (Francoaceae)
  11. Immediate effects of atrazine application on soil organic carbon and selected macronutrients and amelioration by sawdust biochar pretreatment
  12. Process configuration of combined ozonolysis and anaerobic digestion for wastewater treatment
  13. Concentration levels and risk assessment of organochlorine and organophosphate pesticide residue in selected cereals and legumes sold in Anambra State, south-eastern Nigeria
  14. XRD and cytotoxicity assay of submitted nanomaterial industrial samples in the Philippines
  15. Comparative study of the photocatalytic degradation of tetracycline under visible light irradiation using Bi24O31Br11-anchored carbonaceous and silicates catalyst support
  16. Xanthoangelol, geranilated chalcone compound, isolation from pudau leaves (Artocarpus kemando Miq.) as antibacterial and anticancer
  17. Barley thermoplastic starch nanocomposite films reinforced with nanocellulose
  18. Integration of chemo- and bio-catalysis to intensify bioprocesses
  19. Fabrication of starch-based packaging materials
  20. Potato thermoplastic starch nanocomposite films reinforced with nanocellulose
  21. Review on sago thermoplastic starch composite films reinforced with nanocellulose
  22. Wheat thermoplastic starch composite films reinforced with nanocellulose
  23. Synergistic effect in bimetallic gold catalysts: recent trends and prospects
  24. Simultaneous removal of methylene blue, copper Cu(II), and cadmium Cd(II) from synthetic wastewater using fennel-based adsorbents
  25. The investigation of the physical properties of an electrical porcelain insulator manufactured from locally sourced materials
  26. Concentration evaluation and risk assessment of pesticide residues in selected vegetables sold in major markets of Port Harcourt South-South Nigeria
  27. Detection of iodine in aqueous extract of plants through modified Mohr’s method
  28. Exploration of bioactive compounds from Mangifera indica (Mango) as probable inhibitors of thymidylate synthase and nuclear factor kappa-B (NF-Κb) in colorectal cancer management
  29. A new sphingoid derivative from Acacia hockii De Wild (Fabaceae) with antimicrobial and insecticidal properties
  30. Protection of wood against bio-attack and research of new effective and environmental friendly fungicides
  31. Computational investigation of Arbutus serratifolia Salisb molecules as new potential SARS-CoV-2 inhibitors
  32. Exploring the solvation of water molecules around radioactive elements in nuclear waste water treatment
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