Home Effect of gamma irradiation on the physicochemical and rheological properties of enzyme-catalyzed tragacanth-based injectable hydrogels
Article
Licensed
Unlicensed Requires Authentication

Effect of gamma irradiation on the physicochemical and rheological properties of enzyme-catalyzed tragacanth-based injectable hydrogels

  • Moslem Tavakol EMAIL logo , Ebrahim Vasheghani-Farahani EMAIL logo , Mohammad Amin Mohammadifar and Maryam Dehghan-Niri
Published/Copyright: April 12, 2019
Become an author with De Gruyter Brill

Abstract

In the present study, gamma irradiation was applied to promote the mechanical properties of enzyme- mediated in situ forming hydrogels prepared with tyramine-functionalized gum tragacanth (TA-GT). For this purpose, after gamma irradiation of powder or hydrocolloid solution of gum tragacanth (GT), the physiochemical and rheological properties of GT solution, and resultant hydrogel was investigated. In situ forming hydrogels were prepared via horseradish peroxidase catalyzed coupling reaction of TA-GT in the presence of hydrogen peroxide. Gamma irradiation led to a decrease in GT molecular weight and solution viscosity. Also, the solubility of GT improved and the separation of water soluble/swellable part of gum samples became easier, using gamma irradiation. In addition, by gamma irradiation of GT powder at doses of 5–15 kGy, a polymeric solution with higher concentration could be prepared that resulted in the promotion of hydrogels storage modulus. Further increase of irradiation dose did not improve storage modulus due to the extra decrease of gum molecular weight.

References

[1] Nguyen MK, Lee DS. Macromol. Biosci. 2010, 10, 563–579.10.1002/mabi.200900402Search in Google Scholar PubMed

[2] Ruel-Gariépy E, Leroux J-C. Eur. J. Pharm. Biopharm. 2004, 58, 409–426.10.1016/j.ejpb.2004.03.019Search in Google Scholar PubMed

[3] Tan H, Marra KG. Materials 2010, 3, 1746–1767.10.3390/ma3031746Search in Google Scholar

[4] Dewettinck DVSDK. Appl. Microbiol. Biotechnol. 2003, 63, 10–21.10.1007/s00253-003-1354-zSearch in Google Scholar PubMed

[5] Moghbel A, Hemmati AA, Agheli H, Rashidi I, Amraee K. Archiv. Iranian Med. 2005, 8, 257–262.Search in Google Scholar

[6] Sadat Hosseini M, Hemmati K, Ghaemy M. Int. J. Biol. Macromol. 2016, 82, 806–815.10.1016/j.ijbiomac.2015.09.067Search in Google Scholar PubMed

[7] Hemmati K, Ghaemy M. Int. J. Biol. Macromol. 2016, 87, 415–425.10.1016/j.ijbiomac.2016.03.005Search in Google Scholar PubMed

[8] Fattahi A, Sadrjavadi K, Golozar MA, Varshosaz J, Fathi M-H, Mirmohammad-Sadeghi H. Carbohydr. Polym. 2013, 97, 277–283.10.1016/j.carbpol.2013.04.098Search in Google Scholar PubMed

[9] Kiani A, Asempour H. J. Appl. Polym. Sci. 2012, 126, 1477–1484.10.1002/app.36782Search in Google Scholar

[10] Fattahi A, Petrini P, Munarin F, Shokoohinia Y, Golozar MA, Varshosaz J, Tanzi MC. J. Appl. Polym. Sci. 2013, 129, 2092–2102.10.1002/app.38931Search in Google Scholar

[11] Haeri SMJ, Sadeghi Y, Salehi M, Farahani RM, Mohsen N. Biologicals 2016, 44, 123–128.10.1016/j.biologicals.2016.03.004Search in Google Scholar PubMed

[12] Kulanthaivel S, Rathnam VSS, Agarwal T, Pradhan S, Pal K, Giri S, Maiti TK, Banerjee I. J. Mater. Chem. B 2017, 5, 4177–4189.10.1039/C7TB00390KSearch in Google Scholar

[13] Ranjbar-Mohammadi M, Bahrami SH. Mater. Sci. Eng. C 2015, 4871–4879.Search in Google Scholar

[14] Ranjbar-Mohammadi M, Bahrami SH, Joghataei MT. Mater. Sci. Eng. C 2013, 33, 4935–4943.10.1016/j.msec.2013.08.016Search in Google Scholar

[15] Tavakol M, Vasheghani-Farahani E, Soleimani M, Mohammadifar MA, Hashemi-Najafabadi S, Hafizi M. Iranian J. Biotechnol. 2013, 12, 15811.10.5812/ijb.15811Search in Google Scholar

[16] Dehghan-Niri M, Tavakol M, Vasheghani-Farahani E, Ganji F. J. Biomater. Appl. 2015, 29, 1343.10.1177/0885328214568468Search in Google Scholar

[17] Al-Assaf S, Phillips GO, Williams PA, du Plessis TA. Nucl. Instrum. Meth. B. 2007, 265, 37–43.10.1016/j.nimb.2007.08.015Search in Google Scholar

[18] Şen M, Yolaçan B, Güven O. Nucl. Instrum. Meth. B. 2007, 265, 429–433.10.1016/j.nimb.2007.09.033Search in Google Scholar

[19] Hai L, Bang Diep T, Nagasawa N, Yoshii F, Kume T. Nucl. Instrum. Meth. B. 2003, 208, 466–470.10.1016/S0168-583X(03)01181-9Search in Google Scholar

[20] Alijani S, Balaghi S, Mohammadifar MA. Int. J. Biol.Macromol. 2011, 49, 471–479.10.1016/j.ijbiomac.2011.05.030Search in Google Scholar PubMed

[21] Jacobs GP, Simes R. J. Pharm. Pharmacol. 1979, 31, 333–334.10.1111/j.2042-7158.1979.tb13511.xSearch in Google Scholar PubMed

[22] Teimouri S, Abbasi S, Sheikh N. Food Hydrocolloids 2016, 59, 9–16.10.1016/j.foodhyd.2015.12.010Search in Google Scholar

[23] Mohammadifar MA, Musavi SM, Kiumarsi A, Williams PA. Int. J. Biol. Macromol. 2006, 38, 31–39.10.1016/j.ijbiomac.2005.12.015Search in Google Scholar PubMed

[24] Jin R, Moreira Teixeira LS, Dijkstra PJ, van Blitterswijk CA, Karperien M, Feijen J. Biomaterials 2010, 31, 3103–3113.10.1016/j.biomaterials.2010.01.013Search in Google Scholar

[25] Balaghi S, Mohammadifar MA, Zargaraan A. Food Biophys 2010, 5, 59–71.10.1007/s11483-009-9144-5Search in Google Scholar

[26] Yoshii F, Zhao L, Wach RA, Nagasawa N, Mitomo H, Kume T. Nucl. Instrum. Meth. B. 2003, 208, 320–324.10.1016/S0168-583X(03)00624-4Search in Google Scholar

[27] Lee DW, Choi WS, Byun MW, Park HJ, Yu Y-M, Lee CM. J. Agric. Food Chem. 2003, 51, 4819–4823.10.1021/jf021053ySearch in Google Scholar PubMed

[28] Makuuchi K. Radiat. Phys. Chem. 2010, 79, 267–271.10.1016/j.radphyschem.2009.10.011Search in Google Scholar

[29] Moreira Teixeira LS, Feijen J, van Blitterswijk CA, Dijkstra PJ, Karperien M. Biomaterials 2012, 33, 1281–1290.10.1016/j.biomaterials.2011.10.067Search in Google Scholar PubMed

[30] Khanmohammadi M, Dastjerdi MB, Ai A, Ahmadi A, Godarzi A, Rahimi A, Ai J. Biomater. Sci. 2018, 6, 1286–1298.10.1039/C8BM00056ESearch in Google Scholar

Received: 2018-12-07
Accepted: 2019-03-01
Published Online: 2019-04-12
Published in Print: 2019-05-01

©2019 Walter de Gruyter GmbH, Berlin/Boston

Downloaded on 25.9.2025 from https://www.degruyterbrill.com/document/doi/10.1515/polyeng-2018-0366/html
Scroll to top button