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The impact of umbilical and uterine artery Doppler indices on antenatal course, labor and delivery in a low-risk primigravid population
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Sharon M. Cooley
,
Jennifer C. Donnelly
Published/Copyright:
December 3, 2010
Abstract
Aims: To evaluate the impact of umbilical and uterine artery Doppler in the second and third trimester on antenatal course, labor and delivery in a low-risk primigravid population.
Methods: Prospective recruitment of 1011 low-risk primigravidas with uterine and umbilical artery Doppler assessment at 22–24 weeks and 36 weeks. All mothers and infants were reviewed postnatally with a retrospective analysis of ultrasound and clinical outcome data.
Results: Elevated uterine artery indices were associated with increased rates of threatened miscarriage, higher rates of pre-eclampsia (PET) and a higher incidence of fetal birth weight <2nd and 9th centile for gestation. Uterine artery pulsatility index (PI) >95th centile for gestation was associated with statistically higher rates of small-for-gestational age (SGA) infants. Elevated umbilical artery indices were associated with higher rates of induction of labor and a higher incidence of fetal birth weight infants <2nd and 9th centile for gestation. Umbilical artery PI >95th centile for gestation was associated with statistically higher rates of SGA infants.
Conclusion: Elevated uterine and umbilical artery indices are associated with higher rates of maternal and fetal disease.
Received: 2010-4-27
Revised: 2010-7-20
Accepted: 2010-8-20
Published Online: 2010-12-03
Published Online: 2010-12-3
Published in Print: 2011-03-01
©2011 by Walter de Gruyter Berlin New York
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Keywords for this article
Obstetric outcome;
primigravid;
umbilical artery Dopplers;
uterine artery Dopplers
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