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Obstetrical risk factors for focal intestinal perforation in very low birth weight infants

  • Yoshiyuki Nakajima , Naoki Masaoka EMAIL logo and Tatsuo Yamamoto
Published/Copyright: November 15, 2010
Journal of Perinatal Medicine
From the journal Volume 39 Issue 2

Abstract

Objective: Our objective was to determine the obstetrical risk for spontaneous focal intestinal perforation (FIP) in very low birth weight (VLBW) infants.

Methods: Eight mothers delivered infants who underwent laparotomy for FIP between 2001 and 2006 in our hospital. A retrospective case-control study of the eight case mothers and 32 control mothers was conducted. Clinical findings were retrospectively analyzed.

Results: There were significant differences in the frequency of oligohydramnios (P<0.01) and velamentous cord insertion (P<0.05) between cases and controls. The 1-min Apgar score was significantly lower in the FIP group than in the control group (P<0.05). Moreover, primigravidity was significantly associated with a risk of FIP.

Conclusions: The etiology of FIP may be related to changes in the blood circulation, such as fetal hypoxic-ischemic episodes or disturbance in the umbilical blood flow, during the antepartum and/or intrapartum periods.


Corresponding author: Naoki Masaoka, MD Department of Obstetrics and Gynecology Tokyo Women's Medical University Yachiyo Medical Center Chiba 276-8524 Japan

Received: 2010-4-4
Revised: 2010-8-10
Accepted: 2010-8-20
Published Online: 2010-11-15
Published Online: 2010-11-15
Published in Print: 2011-03-01

©2011 by Walter de Gruyter Berlin New York

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