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The role of melatonin in post-partum psychosis and depression associated with bipolar disorder
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George Anderson
Published/Copyright:
August 13, 2010
Abstract
Recent data has highlighted the association of a bipolar disorder (BD) with an increased risk of post-partum psychosis and depression. It is suggested that genetic- and environmental-induced decrease in the levels of melatonin in BD contributes to post-partum disorders. Melatonin may also have some efficacy in the treatment of BD, especially in decreasing the side-effects associated with lithium and the neuroleptics. It is proposed that the optimization of melatonin levels, perhaps in conjunction with optimized vitamin D3 level, would decrease post-partum psychosis and depression associated with BD.
Keywords: Bipolar disorder; melatonin; oxidant status; post-partum depression; post-partum psychosis
Received: 2010-2-24
Revised: 2010-4-13
Accepted: 2010-4-23
Published Online: 2010-08-13
Published Online: 2010-08-13
Published in Print: 2010-11-01
©2010 by Walter de Gruyter Berlin New York
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Keywords for this article
Bipolar disorder;
melatonin;
oxidant status;
post-partum depression;
post-partum psychosis
Articles in the same Issue
- Editorial
- Late motherhood and cesarean delivery
- Review article
- Oxygen and oxidative stress in bronchopulmonary dysplasia
- A statement of the World Association of Perinatal Medicine
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