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Perinatal outcomes in pregnant women with ITP: a single tertiary center experience

  • Huriye Ezveci EMAIL logo , Şükran Doğru , Fatih Akkuş , Fikriye K. Yaman , Emine G. Ünal and Kazım Gezginç
Published/Copyright: July 22, 2024

Abstract

Objectives

In this study, we aimed to compare the maternal and neonatal outcomes in pregnant women diagnosed with idiopathic thrombocytopenic purpura (ITP) in our clinic between different platelet groups.

Methods

This study was designed retrospectively. A total of 62 pregnant women with ITP were included in the study. Demographic and clinical data for all cases were evaluated. Perinatal outcomes were evaluated according to platelet counts.

Results

The median age of the patients participating in the study was 27, and their ages ranged from 21 to 44. ITP was diagnosed before pregnancy in 32.3 % (n=20) of the patients and during pregnancy in 67.7 % (n=42). The average platelet counts of the patients during the first trimester and birth were 104.8/μL (15–168) and 84/μL (16–235), respectively. The average platelet count of newborns is 242/μL. The most common (74.2 %) ITP treatment method is the combination of steroids and IVIG. The platelet count of 80.6 % of newborns is above 151/μL. There was no statistical difference between the results of both mothers and fetuses when the groups were categorized according to maternal platelet levels.

Conclusions

In this study, no difference was observed in maternal and neonatal morbidity and mortality rates, despite the different platelet counts of patients with ITP. The cooperation of the hematology, gynecology, obstetrics, and neonatology departments is responsible for this.


Corresponding author: Huriye Ezveci, MD, Faculty of Medicine, Division of maternal and fetal medicine, Necmettin Erbakan University (NEU), Hocacihan Hocacihan District, Abdülhamid Han Street, No 3, Selçuklu/Konya, Türkiye, E-mail:

  1. Research ethics: The research received approval from the Ethics Committee of Necmettin Erbakan University Meram Faculty of Medicine under decision number 2023/4505 (ID 15499). It was carried out in compliance with national regulations, institutional policies, and the Declaration of Helsinki.

  2. Informed consent: Informed consent was obtained from all individuals included in this study.

  3. Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  4. Competing interests: The authors state no conflict of interest.

  5. Research funding: None declared.

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Received: 2024-03-17
Accepted: 2024-07-07
Published Online: 2024-07-22
Published in Print: 2024-10-28

© 2024 Walter de Gruyter GmbH, Berlin/Boston

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