Breast milk feeding in infants with inherited metabolic disorders other than phenylketonuria – a 10-year single-center experience
-
Karin Pichler
,
Miriam Michel
Abstract
Background:
Published data on breast milk feeding in infants suffering from inherited metabolic disorders (IMDs) other than phenylketonuria (PKU) are limited and described outcome is variable.
Objective:
We aimed to evaluate retrospectively whether breastfeeding and/or breast milk feeding are feasible in infants with IMDs including organic acidemias, fatty acid oxidation disorders, urea cycle disorders, aminoacidopathies or disorders of galactose metabolism.
Methods:
Data on breastfeeding and breast milk feeding as well as monitoring and neurological outcome were collected retrospectively from our database of patients with the mentioned IMD, who were followed in our metabolic center within the last 10 years.
Results:
Twenty patients were included in the study, who were either breast fed on demand or received expressed breast milk. All the infants were evaluated clinically and biochemically at 2–4-week intervals, with weight gain as the leading parameter to determine metabolic control. Good metabolic control and adequate neurological development were achieved in all patients but one, who experienced the only metabolic crisis observed within the study period.
Conclusion:
Breast milk feeding with close clinical and biochemical monitoring is feasible in most IMD and should be considered as it offers nutritional and immunological benefits.
Funding: No funding was received for this study.
References
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The authors stated that there are no conflicts of interest regarding the publication of this article.
©2017 Walter de Gruyter GmbH, Berlin/Boston
Artikel in diesem Heft
- Frontmatter
- Editorial
- Intrapartum care
- Recommendation and Guidelines for Perinatal Practice
- Delivery modes in case of fetal malformations
- Review article
- Obstetric analgesia – update 2016
- Highlight articles
- Risk factors and outcomes in “well-selected” vaginal breech deliveries: a retrospective observational study
- Induction of labor in breech presentation at term: a retrospective cohort study
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- Diagnostic accuracy of fetal scalp lactate for intrapartum acidosis compared with scalp pH
- Reference values for Lactate Pro 2™ in fetal blood sampling during labor: a cross-sectional study
- Linear and non-linear analysis of uterine contraction signals obtained with tocodynamometry in prediction of operative vaginal delivery
- Evaluation of simparteam – a needs-orientated team training format for obstetrics and neonatology
- Transient fetal blood redistribution associated with maternal supine position
- Original articles
- Underlying causes of neonatal deaths in term singleton pregnancies: home births versus hospital births in the United States
- Fourfold increase in prevalence of gestational diabetes mellitus after adoption of the new International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria
- Hematological changes in severe early onset growth-restricted fetuses with absent and reversed end-diastolic flow in the umbilical artery
- Breast milk feeding in infants with inherited metabolic disorders other than phenylketonuria – a 10-year single-center experience
- Clinical significance of a false positive glucose challenge test in patients with a high body mass index
- Obituary
- Obituary – Edward Ogata (1945–2017)
- Congress Calendar
- Congress Calendar
Artikel in diesem Heft
- Frontmatter
- Editorial
- Intrapartum care
- Recommendation and Guidelines for Perinatal Practice
- Delivery modes in case of fetal malformations
- Review article
- Obstetric analgesia – update 2016
- Highlight articles
- Risk factors and outcomes in “well-selected” vaginal breech deliveries: a retrospective observational study
- Induction of labor in breech presentation at term: a retrospective cohort study
- Evaluating fetal head dimension changes during labor using open magnetic resonance imaging
- Risk factors of uterine rupture with a special interest to uterine fundal pressure
- Diagnostic accuracy of fetal scalp lactate for intrapartum acidosis compared with scalp pH
- Reference values for Lactate Pro 2™ in fetal blood sampling during labor: a cross-sectional study
- Linear and non-linear analysis of uterine contraction signals obtained with tocodynamometry in prediction of operative vaginal delivery
- Evaluation of simparteam – a needs-orientated team training format for obstetrics and neonatology
- Transient fetal blood redistribution associated with maternal supine position
- Original articles
- Underlying causes of neonatal deaths in term singleton pregnancies: home births versus hospital births in the United States
- Fourfold increase in prevalence of gestational diabetes mellitus after adoption of the new International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria
- Hematological changes in severe early onset growth-restricted fetuses with absent and reversed end-diastolic flow in the umbilical artery
- Breast milk feeding in infants with inherited metabolic disorders other than phenylketonuria – a 10-year single-center experience
- Clinical significance of a false positive glucose challenge test in patients with a high body mass index
- Obituary
- Obituary – Edward Ogata (1945–2017)
- Congress Calendar
- Congress Calendar
