Ultrasonographic severity scoring of non-immune hydrops: a predictor of perinatal mortality
-
Su Ah Kim
,
Joon-Seok Hong
Abstract
Aim: To develop an ultrasonographic severity scoring of non-immune hydrops in order to predict perinatal outcomes in women with non-immune hydrops.
Methods: The study population consisted of pregnant women who were admitted and delivered with the diagnosis of fetal non-immune hydrops and singleton gestation. Cases were divided into “perinatal survivor” and “perinatal non-survivor” groups. Perinatal non-survivor cases were defined as those with stillbirth or neonatal death ≤28 completed days after birth. The presence of an abnormal fluid collection in each body compartment, such as subcutaneous edema, pleural effusion, pericardial effusion, or ascites was assigned a score of 1 point per each body compartment, and the absence of abnormal fluid collection was scored as 0 point. The total number of abnormal fluid collections was converted to a numeric score, which was called the ultrasonographic severity scoring of non-immune hydrops (USNIH).
Results: Perinatal death occurred in 46.5% (20/43) of the cases of non-immune hydrops. USNIH in patients of the non-survivor group was significantly higher than that in those of the survivor group [non-survivor group 3 (2–4) vs. survivor 2 (2–3); median (range); P<0.05]. Perinatal mortality rates were higher in patients with USNIH ≥3 points than in those with USNIH of 2 points (67% vs. 13%, P<0.005). This difference remained significant after adjustment for confounding variables. When confining analysis to those with idiopathic non-immune hydrops, women in the perinatal non-survivor group had significantly higher USNIH score than those in the perinatal survivor group, and this difference remained significant after adjustment.
Conclusions: Our USNIH system may be a reliable predictive marker for perinatal outcomes in cases of non-immune hydrops, especially in idiopathic hydrops during the antenatal period.
Acknowledgments
The authors would like to thank Sohee Oh, PhD, of the Department of Biostatistics at the Seoul Metropolitan Government Seoul National University Boramae Medical Center, for statistical advice.
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The authors stated that there are no conflicts of interest regarding the publication of this article.
©2015 by De Gruyter
Artikel in diesem Heft
- Frontmatter
- Academy’s Corner
- Maternal mortality: an ongoing challenge to perinatal medicine
- Fetal mild ventriculomegaly: still a challenging problem
- Review article
- Natural killer cell in the developing life
- Original articles – Obstetrics
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- Individual consultant practice does not affect the overall intervention rate: a 6-year study
- Identifying high-risk subgroups for alcohol consumption among younger and older pregnant women
- Ultrasonographic severity scoring of non-immune hydrops: a predictor of perinatal mortality
- Controversial clinical practices for patients with preeclampsia or HELLP syndrome: a survey
- Inter- and intra-observer variability in cervical measurement by ultrasound in the first and second trimesters of pregnancy: does it matter?
- Personnel-itis: a myth or a pathology? A retrospective analysis of obstetrical and perinatal outcomes for physicians and nurses
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- Original article – Fetus
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- Congress Calendar
- Congress Calendar
Artikel in diesem Heft
- Frontmatter
- Academy’s Corner
- Maternal mortality: an ongoing challenge to perinatal medicine
- Fetal mild ventriculomegaly: still a challenging problem
- Review article
- Natural killer cell in the developing life
- Original articles – Obstetrics
- Clinical chorioamnionitis at term I: microbiology of the amniotic cavity using cultivation and molecular techniques
- Individual consultant practice does not affect the overall intervention rate: a 6-year study
- Identifying high-risk subgroups for alcohol consumption among younger and older pregnant women
- Ultrasonographic severity scoring of non-immune hydrops: a predictor of perinatal mortality
- Controversial clinical practices for patients with preeclampsia or HELLP syndrome: a survey
- Inter- and intra-observer variability in cervical measurement by ultrasound in the first and second trimesters of pregnancy: does it matter?
- Personnel-itis: a myth or a pathology? A retrospective analysis of obstetrical and perinatal outcomes for physicians and nurses
- Placenta-secreted circulating markers in pregnant women with obstructive sleep apnea
- Variations of blood cells in prediction of gestational diabetes mellitus
- Peripartum cardiomyopathy – risk factors, characteristics and long-term follow-up
- Original article – Fetus
- Effect of assisted reproductive technology on fetal brain development assessed by prenatal ultrasonography
- Original article – Newborn
- Racial/ethnic differences in the birth prevalence of congenital anomalies in the United States
- Short Communication
- Postnatal kidney maturation regulates renal artery myogenic constriction
- Letters to the Editor
- Ebola viral infection in pregnancy: a plea for specific clinical recommendations
- Magnesium may provide further benefit to hypothermia following perinatal asphyxia encephalopathy
- Congress Calendar
- Congress Calendar
