Startseite Medizin Fetal behavioral states are stable over daytime – evidence by longitudinal and cross-sectional fetal biomagnetic recordings
Artikel
Lizenziert
Nicht lizenziert Erfordert eine Authentifizierung

Fetal behavioral states are stable over daytime – evidence by longitudinal and cross-sectional fetal biomagnetic recordings

  • Alessandra Sonanini , Krunoslav Stingl , Hubert Preissl , Johanna Brändle , Markus Hoopmann , Oliver Kagan , Diethelm Wallwiener , Harald Abele EMAIL logo und Isabelle Kiefer-Schmidt
Veröffentlicht/Copyright: 13. November 2013

Abstract

Aims: Fetal behavioral states can be distinguished by biomagnetic recordings. We performed a longitudinal and a cross-sectional study to address the question whether the distribution of fetal behavioral states changes during the daytime.

Methods: For the longitudinal study, 32 magnetocardiographic recordings were performed on a singleton pregnancy on a weekly basis. On each examination day, two recordings were performed at different times between 25 and 40 weeks of gestation. For the cross-sectional study, fetal magnetocardiograms (fMCG) were recorded in a group of 32 singleton pregnancies matched for gestational age and daytime to the longitudinal study. The recordings were separated into two gestational age groups (less and more than 32 weeks). Fetal behavioral states were extracted from actocardiograms generated from MCG.

Results: No significant differences in fetal behavioral state distribution were found between morning and afternoon recordings in either the longitudinal or the cross-sectional study.

Conclusion: This is the first magnetographic approach to show that daytime does not influence the distribution of fetal behavioral states in standardized recordings of 30 min length. This result implies that fetal magnetography recordings at normal daytimes can be combined without a bias and future recordings can be conducted independently of daytime as long as the varying behavioral states are generally taken into account during analysis.


Corresponding author: Harald Abele, Department of Obstetrics and Gynecology, University Hospital of Tuebingen, Calwerstr. 7, 72076 Tuebingen, Germany, Tel.: +49 7071 2987096, Fax: +49 7071 29 5436, E-mail:

References

[1] Bartsch C, Bartsch H, Lippert TH. Bedeutung der Zirbeldrüse bei Reproduktion und gynäkologischen Tumoren. Geburtshilfe und Frauenheilkunde. 1991;51:1–8.10.1055/s-2008-1026323Suche in Google Scholar

[2] de Vries JI, Visser GH, Mulder EJ, Prechtl HF. Diurnal and other variations in fetal movement and heart rate patterns at 20–22 weeks. Early Hum Dev. 1987;15:333–48.10.1016/0378-3782(87)90029-6Suche in Google Scholar

[3] Drogtrop AP, Ubels R, Nijhuis JG. The association between fetal body movements, eye movements and heart rate patterns in pregnancies between 25 and 30 weeks of gestation. Early Hum Dev. 1990;23:67–73.10.1016/0378-3782(90)90129-7Suche in Google Scholar

[4] Ferreira AJ. Emotional factors in prenatal environment. A review. J Nerv Ment Dis. 1965;141:108–18.10.1097/00005053-196507000-00011Suche in Google Scholar PubMed

[5] Frank B, Pompe B, Schneider U, Hoyer D. Permutation entropy improves fetal behavioural state classification based on heart rate analysis from biomagnetic recordings in near term fetuses. Med Biol Eng Comput. 2006;44:179–87.10.1007/s11517-005-0015-zSuche in Google Scholar PubMed

[6] Govindan RB, Vairavan S, Ulusar UD, Wilson JD, McKelvey SS, Preissl H, et al. A novel approach to track fetal movement using multi-sensor magnetocardiographic recordings. Ann Biomed Eng. 2011;39:964–72.10.1007/s10439-010-0231-zSuche in Google Scholar PubMed PubMed Central

[7] Haddad N, Govindan RB, Vairavan S, Siegel E, Temple J, Preissl H, et al. Correlation between fetal brain activity patterns and behavioral states: an exploratory fetal magnetoencephalography study. Exp Neurol. 2011;228:200–5.10.1016/j.expneurol.2011.01.003Suche in Google Scholar PubMed PubMed Central

[8] Kiefer I, Siegel E, Preissl H, Ware M, Schauf B, Lowery C, et al. Delayed maturation of auditory-evoked responses in growth-restricted fetuses revealed by magnetoencephalographic recordings. Am J Obstet Gynecol. 2008;199:503 e1–7.10.1016/j.ajog.2008.04.014Suche in Google Scholar PubMed PubMed Central

[9] Kiefer-Schmidt I, Lim M, Wacker-Gussmann A, Ortiz E, Abele H, Kagan KO, et al. Fetal magnetocardiography (fMCG): moving forward in the establishment of clinical reference data by advanced biomagnetic instrumentation and analysis. J Perinat Med. 2012;40:277–86.10.1515/jpm.2011.139Suche in Google Scholar PubMed

[10] Kiefer-Schmidt I, Raufer J, Brändle J, Münßinger J, Eswaran H, Birbaumer N, et al. Is there a relation between fetal brain function and the fetal behavioral state? J Perinat Med. 2013;41:605–12.Suche in Google Scholar

[11] Lange S, Van Leeuwen P, Geue D, Hatzmann W, Gronemeyer D. Influence of gestational age, heart rate, gender and time of day on fetal heart rate variability. Med Biol Eng Comput. 2005;43:481–6.10.1007/BF02344729Suche in Google Scholar PubMed

[12] Lange S, Van Leeuwen P, Schneider U, Frank B, Hoyer D, Geue D, et al. Heart rate features in fetal behavioural states. Early Hum Dev. 2009;85:131–5.10.1016/j.earlhumdev.2008.07.004Suche in Google Scholar

[13] Maeda K, Tatsumura M, Utsu M. Analysis of fetal movements by Doppler actocardiogram and fetal B-mode imaging. Clin Perinatol. 1999;26:829–51.10.1016/S0095-5108(18)30022-8Suche in Google Scholar

[14] McCubbin J, Robinson SE, Cropp R, Moiseev A, Vrba J, Murphy P, et al. Optimal reduction of MCG in fetal MEG recordings. IEEE Trans Biomed Eng. 2006;53:1720–4.10.1109/TBME.2006.876619Suche in Google Scholar

[15] McDonald RL. The role of emotional factors in obstetric complications: a review. Psychosom Med. 1968;30:222–43.10.1097/00006842-196803000-00007Suche in Google Scholar

[16] Morokuma S, Horimoto N, Nakano H. Diurnal changes in the power spectral characteristics of eye movements and heart rate variability in the human fetus at term. Early Hum Dev. 2001;64:27–36.10.1016/S0378-3782(01)00168-2Suche in Google Scholar

[17] Mulder EJ, Derks JB, de Laat MW, Visser GH. Fetal behavior in normal dichorionic twin pregnancy. Early Hum Dev. 2012;88:129–34.10.1016/j.earlhumdev.2011.07.011Suche in Google Scholar

[18] Mulder EJ, Ververs FF, de Heus R, Visser GH. Selective serotonin reuptake inhibitors affect neurobehavioral development in the human fetus. Neuropsychopharmacology. 2011;36:1961–71.10.1038/npp.2011.67Suche in Google Scholar

[19] Nijhuis JG, Prechtl HF, Martin CB, Jr., Bots RS. Are there behavioural states in the human fetus? Early Hum Dev. 1982;6:177–95.Suche in Google Scholar

[20] Ozkaya E, Baser E, Cinar M, Korkmaz V, Kucukozkan T. Does diurnal rhythm have an impact on fetal biophysical profile? J Matern Fetal Neonatal Med. 2012;25:335–8.10.3109/14767058.2011.576721Suche in Google Scholar

[21] Patrick J, Challis J, Campbell K, Carmichael L, Natale R, Richardson B. Circadian rhythms in maternal plasma cortisol and estriol concentrations at 30 to 31, 34 to 35, and 38 to 39 weeks’ gestational age. Am J Obstet Gynecol. 1980;136: 325–34.10.1016/0002-9378(80)90857-1Suche in Google Scholar

[22] Pillai M, James D. Development of human fetal behavior: a review. Fetal Diagn Ther. 1990;5:15–32.10.1159/000263530Suche in Google Scholar PubMed

[23] Pillai M, James D. Behavioural states in normal mature human fetuses. Arch Dis Child. 1990;65:39–43.10.1136/adc.65.1_Spec_No.39Suche in Google Scholar

[24] Pillai M, James D. The development of fetal heart rate patterns during normal pregnancy. Obstet Gynecol. 1990;76:812–6.10.1097/00006250-199011000-00017Suche in Google Scholar

[25] Pillai M, James D. The importance of the behavioural state in biophysical assessment of the term human fetus. Br J Obstet Gynaecol. 1990;97:1130-4.10.1111/j.1471-0528.1990.tb02501.xSuche in Google Scholar

[26] Pillai M, James DK, Parker M. The development of ultradian rhythms in the human fetus. Am J Obstet Gynecol. 1992;167:172–7.10.1016/S0002-9378(11)91654-8Suche in Google Scholar

[27] Romanini C, Rizzo G. Fetal behaviour in normal and compromised fetuses. An overview. Early Hum Dev. 1995;43:117–31.10.1016/0378-3782(95)01667-8Suche in Google Scholar

[28] Schleussner E, Schneider U. Developmental changes of auditory-evoked fields in fetuses. Exp Neurol. 2004;190 (Suppl 1):S59–64.10.1016/j.expneurol.2004.04.008Suche in Google Scholar PubMed

[29] Schneider KTM, Butterwegge M, Daumer M, Dudenhausen J, Gonser M, Husslein P, et al. Use of CTG during pregnancy and childbirth. DGGG-Leitlinienregister 2011: AWMF: 015/036 (S1).Suche in Google Scholar

[30] Schneider U, Frank B, Fiedler A, Kaehler C, Hoyer D, Liehr M, et al. Human fetal heart rate variability-characteristics of autonomic regulation in the third trimester of gestation. J Perinat Med. 2008;36:433–41.10.1515/JPM.2008.059Suche in Google Scholar PubMed

[31] Schneider H, Husslein P, Schneider KTM. Die Geburtshilfe. Heidelberg: Springer; 2004. p. 553–5.10.1007/978-3-642-18574-8Suche in Google Scholar

[32] Sheridan CJ, Matuz T, Draganova R, Eswaran H, Preissl H. Fetal magnetoencephalography – achievements and challenges in the study of prenatal and early postnatal brain responses: a review. Infant Child Dev. 2010;19:80–93.10.1002/icd.657Suche in Google Scholar PubMed PubMed Central

[33] Suwanrath C, Suntharasaj T. Sleep-wake cycles in normal fetuses. Arch Gynecol Obstet. 2010;281:449–54.10.1007/s00404-009-1111-3Suche in Google Scholar PubMed

[34] Van Leeuwen P, Cysarz D, Edelhauser F, Gronemeyer D. Heart rate variability in the individual fetus. Auton Neurosci. 2013;178:24–8.10.1016/j.autneu.2013.01.005Suche in Google Scholar

[35] Van Leeuwen P, Geue D, Lange S, Hatzmann W, Gronemeyer D. Changes in the frequency power spectrum of fetal heart rate in the course of pregnancy. Prenat Diagn. 2003;23:909–16.10.1002/pd.723Suche in Google Scholar

[36] Visser GH, Goodman JD, Levine DH, Dawes GS. Diurnal and other cyclic variations in human fetal heart rate near term. Am J Obstet Gynecol. 1982;142:535–44.10.1016/0002-9378(82)90757-8Suche in Google Scholar

The authors stated that there are no conflicts of interest regarding the publication of this article.

Received: 2013-7-21
Accepted: 2013-10-9
Published Online: 2013-11-13
Published in Print: 2014-5-1

©2014 by Walter de Gruyter Berlin Boston

Artikel in diesem Heft

  1. Frontmatter
  2. Editorial
  3. Academy’s Corner – a new section at JPM
  4. Academy’s Corner
  5. Global education in perinatal medicine: will the bureaucracy or smartocracy prevail?
  6. Review articles
  7. Placental chorioangioma: literature review
  8. Sonographic measurement of cervical length as a predictor of preterm delivery: a systematic review
  9. Original articles – Obstetrics
  10. Peripartum anesthetic management of patients with Factor XI deficiency
  11. Risk of inferior vena cava compression syndrome during fetal MRI in the supine position – a retrospective analysis
  12. Fetal behavioral states are stable over daytime – evidence by longitudinal and cross-sectional fetal biomagnetic recordings
  13. Diet or medically treated gestational diabetes: is there any difference for obstetrical and neonatal complications? A French cohort study
  14. Cerebroplacental Doppler ratio and placental histopathological features in pregnancies complicated by fetal growth restriction
  15. Placental syndecan-1 and sulphated glycosaminoglycans are decreased in preeclampsia
  16. Pharmacological anti-thrombotic prophylaxis after elective caesarean delivery in thrombophilia unscreened women: should maternal age have a role in decision making?
  17. Values of T/QRS ratios measured during normal and post-term pregnancies
  18. The factors associated with the failure of transcatheter pelvic arterial embolization for intractable postpartum hemorrhage
  19. Hysteroscopic and laparoscopic management of uterine defects on previous cesarean delivery scars
  20. Chemerin concentrations in maternal and fetal compartments: implications for metabolic adaptations to normal human pregnancy
  21. Repetitive administration of acetylcholine receptor agonist rescues brain inflammation and brain damage after hypoxia-ischemia in newborn rat
  22. Original article – Fetus
  23. Fetal hydronephrosis: natural history and risk factors for postnatal surgery
  24. Original article – Newborn
  25. Cytomegalovirus infection among infants in California neonatal intensive care units, 2005–2010
  26. Letter to the Editors
  27. Origin of the long-term variability and acceleration of FHR studied for the prevention of cerebral palsy in fetal hypoxia and general insults
  28. Neonatal phototherapy, fluids, and photorelaxation
  29. Congress Calendar
  30. Congress Calendar
Heruntergeladen am 14.12.2025 von https://www.degruyterbrill.com/document/doi/10.1515/jpm-2013-0180/pdf
Button zum nach oben scrollen