Body composition assessment measured via bioelectrical impedance analysis in euthyroid children with newly diagnosed Hashimoto’s thyroiditis
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Serkan Bilge Koca
,
Tarik Kirkgoz
and
Leyla Kara
Abstract
Objectives
The effects of thyroid hormones on body composition are well-known. We aimed to examine the body composition of children with and without Hashimoto’s thyroiditis (HT) by bioelectrical impedance analysis (BIA) while they were still euthyroid.
Methods
Between the ages of 5 and 18, 53 girls and 12 boys in each group, 65 children with HT, and 65 healthy children were included in this study. The Tanita MC-780 MA model was used to evaluate body composition parameters. These are fat mass (FM), fat-free mass (FFM), muscle mass (MM), bone mass (BM), total body water (TBW), phase angle, the ratio of muscle mass to fat mass (MFR), basal metabolic rate (BMR), and sarcopenic index (SI). Weight, height, body mass index standard deviation scores (SDSs), and pubertal status were examined. Additionally, TSH, Free-T4, Free-T3, Anti-TPO, Anti-Tg, serum lipid levels, and thyroid volumes were compared.
Results
We observed that TBW (27.5 ± 7.5 kg vs. 24.8 ± 6.6 kg; p=0.029) and BMR (1,403 ± 253 kcal vs. 1,324 ± 200 kcal; p=0.049) were higher in the HT group. These differences are due to differences in age and muscle mass in the male group. The FM, FFM, MM, BM, MFR, SI, and phase angle scores did not differ between females with and without HT in euthyroid children by the BIA method.
Conclusions
There is no significant change in body composition in euthyroid females with HT at admission.
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Research ethics: The local Institutional Review Board approved the study.
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Informed consent: Informed consent was obtained from all individuals included in this study.
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Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
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Use of Large Language Models, AI and Machine Learning Tools: None declared.
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Conflict of interest: Authors state no conflict of interest.
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Research funding: None declared.
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Data availability: Not applicable.
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Articles in the same Issue
- Frontmatter
- Review
- Osteogenesis imperfecta: shifting paradigms in pathophysiology and care in children
- Opinion Paper
- CRH receptor antagonist crinecerfont – a promising new treatment option for patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency
- Original Articles
- Age and sex mark clinical differences in the presentation of pediatric type 1 diabetes mellitus
- Geographic information system mapping and predictors of glycemic control in children and youth with type 1 diabetes: a study from Western India
- Body composition assessment measured via bioelectrical impedance analysis in euthyroid children with newly diagnosed Hashimoto’s thyroiditis
- Outcomes of newborns screened for congenital hypothyroidism in Turkey – a single center experience
- High yield of congenital hypothyroidism among infants attending Children Hospital, Nairobi, Kenya. Facility based study in the absence of newborn screening
- Immune checkpoint inhibitors and endocrinopathies in pediatric brain tumor patients
- Assessment of quality of life in families affected by maple syrup urine disease: a cross sectional study
- Case Reports
- Reninoma: an unusual cause of growth failure
- Persistent hypoglycemia in congenital syphilis: hyperinsulinemic hypoglycemia with a focal pancreatic lesion
- Diagnostic challenges in pediatric Cushing’s disease associated with chronic renal failure: a report of three patients
- A novel de novo missense OTC mutation in an Iranian girl: a case report
