Implementation of IT supported standardization of individualized hydrocortisone management for treatment of patients with adrenal insufficiency
-
Varshini Chakravarthy
, Katie Barger
Abstract
Objectives
Hydrocortisone stress dosing guidelines for children with adrenal insufficiency (AI) recommend a wide range of acceptable stress doses. This has led to variability in dosing recommendations resulting in confusion among endocrine, non-endocrine providers and patient families. This quality improvement project sought to standardize documentation and hydrocortisone stress dosing within our pediatric endocrine division to optimize communication regarding AI management.
Methods
Plan-Do-Study-Act (PDSA) cycle one aimed to address documentation of components important in AI management including body surface area (BSA), home daily dose, home stress dose, in-patient stress dose, procedure dose and crisis dose using a smart phrase within the electronic health record (EHR). To automate the process, PDSA cycle two introduced two smart buttons within the endocrine notes. PDSA cycle three focused on standardizing hydrocortisone stress doses.
Results
Initial documentation targets were met for all AI management components except for the crisis dose. The second target was only met for the home stress dose. Implementing the smart buttons aided in reaching the second target for home daily and home stress doses. Dose standardization targets were achieved in all categories except for the on-going crisis dose. A follow up survey after an in-service for non-endocrine providers showed increased knowledge of locating hydrocortisone stress dosing recommendations within the EHR.
Conclusions
With the assistance of technology, this quality improvement project ultimately enhanced communication through the standardization of documentation and individualized hydrocortisone stress dosing for children with AI. Although not all secondary targets were met, there was meaningful improvement in documentation and stress dose standardization compliance.
Acknowledgments
We would like to thank Dr. Wendy Arafiles for adding the Complex Care Button and for her work on helping us improve patient care for our patients with AI. We would also like to thank Shelley Flecky and Cliff Fortner for their work on implementing the smart button into the electronic medical record outpatient note as well as the endocrine clinicians for their participation and insightful feedback. Lastly, we would like to thank Dr. Victoria Bernaud and Dr. Ted Swing for their feedback on the manuscript.
-
Research ethics: This study has been granted an exemption from requiring ethics approval by Phoenix Children’s Institutional Review Board.
-
Informed consent: This study has been granted an exemption from requiring written informed consent by Phoenix Children’s Institutional Review Board.
-
Author contributions: VC was involved with data collection, analysis and preparation of the table and figure. VC, KB, RB, GQ, CK, and VV drafted and wrote the manuscript. All authors approved the submitted version of the manuscript.
-
Competing interests: Authors state no conflict of interest.
-
Research funding: None declared.
References
1. Miller, W, Fluck, C. Adrenal cortex and its disorderes. In: Sperling, M, editor. Pediatric Endocrinology, 4th ed. Philadelphia: Elsevier Saunders; 2014:471–532 pp.10.1016/B978-1-4557-4858-7.00022-6Suche in Google Scholar
2. Hsu, AA, Von Elten, K, Chan, D, Flynn, T, Walker, K, Barnhill, J, et al.. Characterization of the cortisol stress response to sedation and anesthesia in children. J Clin Endocrinol Metab 2012;97:1830–5. https://doi.org/10.1210/jc.2012-1499.Suche in Google Scholar PubMed
3. Miller, BS, Spencer, SP, Geffner, ME, Gourgari, E, Lahoti, A, Kamboj, MK, et al.. Emergency management of adrenal insufficiency in children: advocating for treatment options in outpatient and field settings. J Invest Med 2020;68:16–25. https://doi.org/10.1136/jim-2019-000999.Suche in Google Scholar PubMed PubMed Central
4. Bornstein, SR, Allolio, B, Arlt, W, Barthel, A, Don-Wauchope, A, Hammer, GD, et al.. Diagnosis and treatment of primary adrenal insufficiency: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 2016;101:364–89. https://doi.org/10.1210/jc.2015-1710.Suche in Google Scholar PubMed PubMed Central
5. Ahmet, A, Rowan-Legg, A, Pancer, L. Adrenal suppression from exogenous glucocorticoids: recognizing risk factors and preventing morbidity. Paediatr Child Health 2021;26. https://doi.org/10.1093/pch/pxab015.Suche in Google Scholar PubMed PubMed Central
6. Mushtaq, T, Ali, SR, Boulos, N, Boyle, R, Cheetham, T, Davies, JH, et al.. Emergency and perioperative management of adrenal insufficiency in children and young people: British society for paediatric endocrinology and diabetes consensus guidance. Arch Dis Child 2023. https://doi.org/10.1136/archdischild-2022-325156.Suche in Google Scholar PubMed PubMed Central
7. Rozich, JD, Howard, RJ, Justeson, JM, Macken, PD, Lindsay, ME, Resar, RK. Standardization as a mechanism to improve safety in health care. Jt Comm J Qual Saf 2004;30:5–14. https://doi.org/10.1016/s1549-3741(04)30001-8.Suche in Google Scholar PubMed
Supplementary Material
This article contains supplementary material (https://doi.org/10.1515/jpem-2023-0313).
© 2023 Walter de Gruyter GmbH, Berlin/Boston
Artikel in diesem Heft
- Frontmatter
- Review
- Intracranial germ cell tumors: a view of the endocrinologist
- Original Articles
- Technology use and clinical outcomes in a racial-ethnic minority cohort of children and adolescents with type 1 diabetes
- The use of CGM to identify hypoglycemia and glycemic patterns in congenital hyperinsulinism
- The N221D variant in PCSK1 is highly prevalent in childhood obesity and can influence the metabolic profile
- Evaluation of the risk factors for noncommunicable diseases in patients with inborn errors of amino acid metabolism receiving nutrition therapy
- Features of liver injury in 138 Chinese patients with NICCD
- A case-control study of early-stage radiological markers of endothelial dysfunction and cardiovascular findings in patients with osteogenesis imperfecta: genotype–phenotype correlations
- Caregivers’ knowledge and medication adherence in children with thyroid disorders: an exploratory study
- Implementation of IT supported standardization of individualized hydrocortisone management for treatment of patients with adrenal insufficiency
- Interdisiplinary and intraobserver reliability of the Greulich-Pyle method among Turkish children
- Case Report
- Alpha-mannosidosis: a case with novel ultrastructural and light microscopy findings
- Letters to the Editor
- Reply to: The relationship between estrogen and subsequent growth restriction among adolescents with heavy menstrual bleeding at menarche
- In reply re: The relationship between estrogen and subsequent growth restriction among adolescents with heavy menstrual bleeding at menarche
Artikel in diesem Heft
- Frontmatter
- Review
- Intracranial germ cell tumors: a view of the endocrinologist
- Original Articles
- Technology use and clinical outcomes in a racial-ethnic minority cohort of children and adolescents with type 1 diabetes
- The use of CGM to identify hypoglycemia and glycemic patterns in congenital hyperinsulinism
- The N221D variant in PCSK1 is highly prevalent in childhood obesity and can influence the metabolic profile
- Evaluation of the risk factors for noncommunicable diseases in patients with inborn errors of amino acid metabolism receiving nutrition therapy
- Features of liver injury in 138 Chinese patients with NICCD
- A case-control study of early-stage radiological markers of endothelial dysfunction and cardiovascular findings in patients with osteogenesis imperfecta: genotype–phenotype correlations
- Caregivers’ knowledge and medication adherence in children with thyroid disorders: an exploratory study
- Implementation of IT supported standardization of individualized hydrocortisone management for treatment of patients with adrenal insufficiency
- Interdisiplinary and intraobserver reliability of the Greulich-Pyle method among Turkish children
- Case Report
- Alpha-mannosidosis: a case with novel ultrastructural and light microscopy findings
- Letters to the Editor
- Reply to: The relationship between estrogen and subsequent growth restriction among adolescents with heavy menstrual bleeding at menarche
- In reply re: The relationship between estrogen and subsequent growth restriction among adolescents with heavy menstrual bleeding at menarche