An extremely high blood glucose level in a child with hyperglycemic hyperosmolar state and type 1 diabetes
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Ivona Butorac Ahel
, Srecko Severinski
Abstract
Objectives
Hyperglycemic hyperosmolar state (HHS) is one of the most severe acute complications of diabetes mellitus (DM) characterized by severe hyperglycemia and hyperosmolality without significant ketosis and acidosis. What is new? Since HHS in the pediatric population is rare and potentially life-threatening, every reported case is very valuable for raising awareness among healthcare professionals.
Case presentation
A 7-year-old boy with previously diagnosed Joubert syndrome was admitted due to vomiting, polydipsia and polyuria started several days earlier. He was severely dehydrated, and the initial blood glucose level was 115 mmol/L. Based on clinical manifestations and laboratory results, he was diagnosed with T1DM and HHS. The treatment with intravenous fluid was started and insulin administration began later. He was discharged after 10 days without any complications related to HHS.
Conclusions
Since HHS has a high mortality rate, early recognition, and proper management are necessary for a better outcome.
References
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Articles in the same Issue
- Frontmatter
- Original Articles
- Clinical characteristics and treatment patterns with histrelin acetate subcutaneous implants vs. leuprolide injections in children with precocious puberty: a real-world study using a US claims database
- High serum neurotensin level in obese adolescents is not associated with metabolic parameters, hyperphagia or food preference
- Increased lipocalin 2 levels in adolescents with type 2 diabetes mellitus
- Clinical, biochemical, and radiological follow-up results of children and adolescents with Hashimoto’s thyroiditis: a single-center experience
- Evaluation of children with type 1 diabetes mellitus in terms of overweight/obesity in tertiary care hospital
- Association between anthropometric measures and insulin resistance in Brazilian adolescents: data from the national study of cardiovascular risk factors in adolescents – ERICA
- Evaluation of metabolic parameters and aortic elasticity in normotensive children with premature adrenarche
- Molecular and clinical findings of Turkish patients with hereditary fructose intolerance
- Quantitation and evaluation of perinatal medium-chain and long-chain acylcarnitine blood concentrations in 12,000 full-term breastfed newborns
- Metabolic syndrome and cardiorespiratory fitness in children and adolescents: the role of obesity as a mediator
- Short Communication
- Transient neonatal hyperinsulinism: early predictors of duration
- Case Reports
- An extremely high blood glucose level in a child with hyperglycemic hyperosmolar state and type 1 diabetes
- Different clinical entities of the same mutation: a case report of three sisters with Wolfram syndrome and efficacy of dipeptidyl peptidase-4 inhibitor therapy
- Short report: craniosynostosis, a late complication of nutritional rickets
- Childhood obesity as a safeguarding issue: positive experiences with the “new home” environment as a treatment for weight management