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Oral health status of children with phenylketonuria

  • Elif Ballikaya ORCID logo EMAIL logo , Yilmaz Yildiz ORCID logo , Hatice Serap Sivri ORCID logo , Aysegul Tokatli , Ali Dursun ORCID logo , Seval Olmez ORCID logo , Turgay Coskun und Meryem Uzamis Tekcicek ORCID logo
Veröffentlicht/Copyright: 12. Februar 2020

Abstract

Background

Diet plays an integral role in the maintenance of oral health, but dietary modifications due to medical problems such as phenylketonuria (PKU) can have adverse effects on oral health. This descriptive study was performed to evaluate the oral health status of children with PKU.

Methods

One hundred and ninety-seven patients with PKU aged between 1 and 22 years were evaluated. Clinical evaluations were performed by one experienced dentist regarding dental caries, gingival health and dental erosion. Categorical variables were assessed with descriptive statistics. Differences in feeding frequencies and sociodemographic characteristics were compared regarding dental caries using chi-square (χ2) tests.

Results

One hundred and thirty-two patients (67%) had dental caries. The mean plaque index (PI) and gingival index (GI) values were 1.37 ± 0.58 and 1.40 ± 0.64, respectively, which shows moderate plaque accumulation and moderate gingival inflammation. Of the patients, 85.3% did not brush their teeth regularly and 90.4% had never visited a dentist before. No statistically significant differences were found in dental caries according to feeding frequencies (p = 0.448).

Conclusions

Despite the high prevalence of caries in patients with PKU, most had never seen a dentist. Physicians must encourage patients with PKU and their parents to have regular dental visits to maintain an optimal general and oral health.


Corresponding author: Elif Ballikaya, DDS, Department of Pediatric Dentistry, Faculty of Dentistry, Hacettepe University, Ankara 06230, Turkey

  1. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Employment or leadership: None declared.

  4. Honorarium: None declared.

  5. Competing interests: None declared.

References

1. Blau N, van Spronsen FJ, Levy HL. Phenylketonuria. Lancet 2010;376:1417–27.10.1016/S0140-6736(10)60961-0Suche in Google Scholar

2. Ozalp I, Coşkun T, Tokatli A, Kalkanoğlu H, Dursun A, et al. Newborn PKU screening in Turkey: at present and organization for future. Turkish J Pediatr 2001;43:97–101.Suche in Google Scholar

3. Kilpatrick NM, Awang H, Wilcken B, Christodonoulou J. The implications of Phenylketonuria on oral health. Paediatr Dent 1999;21:433–8.Suche in Google Scholar

4. Moursi AM, Fernandez JB, Daronch M, Zee L, Jones CL. Nutrition and oral health considerations in children with special health care needs: implications for oral health care providers. Paediatr Dent 2010;32:333–42.Suche in Google Scholar

5. Wang K, Shen M, Li H, Li X, He C. Reduced bone mineral density in Chinese children with phenylketonuria. J Pediatr Endocrinol Metab 2017;30:651–6.10.1515/jpem-2016-0308Suche in Google Scholar PubMed

6. World Health Organization. Oral health surveys: basic methods. Geneva: World Health Organization, 2013.Suche in Google Scholar

7. Silness J, Löe H. Periodontal disease in pregnancy II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 1964;22:121–35.10.3109/00016356408993968Suche in Google Scholar PubMed

8. Touger-Decker R, Mobley CC. Position of the American Dietetic Association: oral health and nutrition. J Am Diet Assoc 2007;107:1418–28.10.1016/j.jada.2007.06.003Suche in Google Scholar PubMed

9. Przyrembel H, Bremer H-J. Nutrition, physical growth, and bone density in treated phenylketonuria. Eur J Pediatr 2000;159:S129–35.10.1007/PL00014376Suche in Google Scholar PubMed

10. Lucas VS, Contreras A, Loukissa M, Roberts GJ. Dental disease indices and caries related oral microflora in children with phenylketonuria. ASDC J Dent Child 2001;68:263–7.Suche in Google Scholar

11. Winter G, Murray J, Goose D. Prevalence of dental caries in phenylketonuric children. Caries Res 1974;8:256–66.10.1159/000260114Suche in Google Scholar PubMed

12. Singh-Hüsgen P, Meissner T, Bizhang M, Henrich B, Raab WH. Investigation of the oral status and microorganisms in children with phenylketonuria and type 1 diabetes. Clinical Oral Investig 2016;20:841–7.10.1007/s00784-015-1564-7Suche in Google Scholar PubMed

13. Gökalp S, Guciz Dogan B, Tekçiçek M, Berberoglu A, Ünlüer Ş. National survey of oral health status of children and adults in Turkey. Community Dent Hlth 2010;27:12–7.Suche in Google Scholar

14. Namal N, Vehit HE, Can G. Risk factors for dental caries in Turkish preschool children. J Indian Soc Pedod Prev Dent 2005;23:115–8.10.4103/0970-4388.16881Suche in Google Scholar PubMed

15. Adair SM. Dietary counseling-time for a nutritionist in the office? Paediatr Dent 2004;26:389.Suche in Google Scholar

16. American Academy on Pediatric Dentistry Clinical Affairs Committee, American Academy on Pediatric Dentistry Council on Clinical Affairs. Policy on dietary recommendations for infants, children, and adolescents. Paediatr Dent 2008;30:47–8.Suche in Google Scholar

Received: 2019-09-20
Accepted: 2020-01-01
Published Online: 2020-02-12
Published in Print: 2020-03-26

©2020 Walter de Gruyter GmbH, Berlin/Boston

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