Abstract
Background:
The aim of this study was to compare the oral health status of children with type 1 diabetes and healthy controls.
Methods:
This comparative study involved 64 children, 32 children with type 1 diabetes and 32 age- and gender-matched controls. Oral health examination was conducted using WHO criteria. Dental caries experience was recorded using DMFT/dmft index and periodontal parameters were assessed using plaque, gingivitis, gingival bleeding and calculus indexes. Dental caries and periodontal parameters between the two groups were compared using the Mann-Whitney U-test.
Results:
Children with diabetes exhibited significantly greater plaque deposits (p=0.01) and a higher mean plaque index (p<0.01), when compared to healthy subjects. No significant difference in DMFT and dmft scores, mean bleeding index, calculus index and gingival index was found between the two groups.
Conclusions:
Children with type 1 diabetes had a poor oral health status with greater plaque accumulation than children without diabetes.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: None declared.
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
References
1. Karam JH. Pancreatic hormones and diabetes mellitus. In: Greenspan FS, Strewler GJ, editors. Basic and clinical endocrinology. 5th ed. New Jersey: Appleton and Lange, 1997:595–663.Search in Google Scholar
2. Alemzadeh R, Wyatt D. Diabetes mellitus. In: Behrman RE, Kliegman RM, Jenson HB, editors. Nelson textbook of pediatrics. 17th ed. Philadelphia, PA: WB Saunders, 2004:1947–72.Search in Google Scholar
3. Karvonen M, Tuomilehto J, Libman I, LaPorte R. A review of the recent epidemiological data on the worldwide incidence of type 1 (insulin-dependent) diabetes mellitus. World Health Organization DIAMOND Project Group. Diabetologia 1993;36:883–92.10.1007/BF02374468Search in Google Scholar PubMed
4. Harjutsalo V, Sjoberg L, Tuomilehto J. Time trends in the incidence of type 1 diabetes in Finnish children: a cohort study. Lancet 2008;371:1777–82.10.1016/S0140-6736(08)60765-5Search in Google Scholar PubMed
5. Ehehalt S, Blumenstock G, Willasch AM, Hub R, Ranke MB, et al. Continuous rise in incidence of childhood type 1 diabetes in Germany. Diabet Med 2008;25:755–7.10.1111/j.1464-5491.2008.02450.xSearch in Google Scholar PubMed
6. Fourlanos S, Varney MD, Tait BD, Morahan G, Honeyman MC, et al. The rising incidence of type 1 diabetes is accounted for by cases with lower-risk human leukocyte antigen genotypes. Diabetes Care 2008;31:1546–9.10.2337/dc08-0239Search in Google Scholar PubMed PubMed Central
7. Cherian MP, Al-Kanani KA, Al Qahtani SS, Yesurathinam H, Mathew AA, et al. The rising incidence of type 1 diabetes mellitus and the role of environmental factors–three decade experience in a primary care health center in Saudi Arabia. J Pediatr Endocrinol Metab 2010;23:685–95.10.1515/JPEM.2010.23.7.685Search in Google Scholar
8. Dorman JS, LaPorte RE. Mortality in insulin-dependent diabetes. In: Diabetes in America, United States Department of Health and Human Services 1985:1–9. (NIH Publication No. 85–1468).Search in Google Scholar
9. Castle WM, Wicks AC. A follow-up of 93 newly diagnosed African diabetics for 6 years. Diabetologia 1980;18:121–3.10.1007/BF00290487Search in Google Scholar PubMed
10. Samardzic M, Tahirovic H, Popovic N, Popovic-Samardzic M. Health-related quality of life in children and adolescents with type 1 diabetes mellitus from Montenegro: relationship to metabolic control. J Pediatr Endocrinol Metab 2016;29:663–8.10.1515/jpem-2015-0420Search in Google Scholar PubMed
11. Jayashree M, Singhi S. Diabetic ketoacidosis: predictors of outcome in a pediatric intensive care unit of a developing country. Pediatr Crit Care Med 2004;5:427–33.10.1097/01.PCC.0000137987.74235.5ESearch in Google Scholar
12. Orbak R, Simsek S, Orbak Z, Kavrut F, Colak M. The influence of type-1 diabetes mellitus on dentition and oral health in children and adolescents. Yonsei Med J 2008;49:357–65.10.3349/ymj.2008.49.3.357Search in Google Scholar PubMed PubMed Central
13. Listgarten MA, Ricker FH Jr, Laster L, Shapiro J, Cohen DW. Vascular basement lamina thickness in the normal and inflamed gingiva of diabetics and non-diabetics. J Periodontol 1974;45:676–84.10.1902/jop.1974.45.9.676Search in Google Scholar PubMed
14. Al-Khabbaz AK, Al-Shammari KF, Hasan A, Abdul-Rasoul M. Periodontal health of children with type 1 diabetes mellitus in Kuwait: a case-control study. Med Princ Pract 2013;22:144–9.10.1159/000342624Search in Google Scholar PubMed PubMed Central
15. El-Tekeya M, El Tantawi M, Fetouh H, Mowafy E, Abo Khedr N. Caries risk indicators in children with type 1 diabetes mellitus in relation to metabolic control. Pediatr Dent 2012;34:510–6.Search in Google Scholar PubMed
16. Siudikiene J, Maciulskiene V, Dobrovolskiene R, Nedzelskiene I. Oral hygiene in children with type I diabetes mellitus. Stomatologija 2005;7:24–7.Search in Google Scholar PubMed
17. Alves C, Menezes R, Brandao M. Salivary flow and dental caries in Brazilian youth with type 1 diabetes mellitus. Indian J Dent Res 2012;23:758–62.10.4103/0970-9290.111254Search in Google Scholar PubMed
18. Rai K, Hegde AM, Kamath A, Shetty S. Dental caries and salivary alterations in type I diabetes. J Clin Pediatr Dent 2011;36:181–4.10.17796/jcpd.36.2.x436ln878221g364Search in Google Scholar PubMed
19. Siudikiene J, Machiulskiene V, Nyvad B, Tenovuo J, Nedzelskiene I. Dental caries and salivary status in children with type 1 diabetes mellitus, related to the metabolic control of the disease. Eur J Oral Sci 2006;114:8–14.10.1111/j.1600-0722.2006.00277.xSearch in Google Scholar PubMed
20. Tagelsir A, Cauwels R, van Aken S, Vanobbergen J, Martens LC. Dental caries and dental care level (restorative index) in children with diabetes mellitus type 1. Int J Paediatr Dent 2011;21:13–22.10.1111/j.1365-263X.2010.01094.xSearch in Google Scholar PubMed
21. Swanljung O, Meurman JH, Torkko H, Sandholm L, Kaprio E, et al. Caries and saliva in 12-18-year-old diabetics and controls. Scand J Dent Res 1992;100:310–3.10.1111/j.1600-0722.1992.tb01077.xSearch in Google Scholar PubMed
22. Firatli E. The relationship between clinical periodontal status and insulin-dependent diabetes mellitus. Results after 5 years. J Periodontol 1997;68:136–40.10.1902/jop.1997.68.2.136Search in Google Scholar PubMed
23. WHO. Oral health surveys-basic methods. 3rd ed. Geneva: World Health Organization 1987.Search in Google Scholar
24. Silness J, Loe H. Periodontal disease in pregnancy. ii. Correlation between oral hygiene and periodontal condtion. Acta Odontol Scand 1964;22:121–35.10.3109/00016356408993968Search in Google Scholar PubMed
25. Loe H, Silness J. Periodontal disease in pregnancy. i. Prevalence and severity. Acta Odontol Scand 1963;21:533–51.10.3109/00016356309011240Search in Google Scholar PubMed
26. Ainamo J, Bay I. Problems and proposals for recording gingivitis and plaque. Int Dent J 1975;25:229–35.Search in Google Scholar PubMed
27. Greene JC, Vermillion JR. The oral hygiene index: a method for classifying oral hygiene status. J Am Dent Assoc 1960;61:172–9.10.14219/jada.archive.1960.0177Search in Google Scholar
28. Rankin G, Stokes M. Reliability of assessment tools in rehabilitation: an illustration of appropriate statistical analyses. Clin Rehabil 1998;12:187–99.10.1191/026921598672178340Search in Google Scholar PubMed
29. Huen KF, Low LC, Wong GW, Tse WW, Yu AC, et al. Epidemiology of diabetes mellitus in children in Hong Kong: the Hong Kong childhood diabetes register. J Pediatr Endocrinol Metab 2000;13:297–302.10.1515/JPEM.2000.13.3.297Search in Google Scholar
30. Huen KF, Low LCK, Cheung PT, Wong GW, But WM, et al. An update on the epidemiology of childhood diabetes in Hong Kong. HK J Paediatr 2009;14:252–9.Search in Google Scholar
31. Lalla E, Cheng B, Lal S, Tucker S, Greenberg E, et al. Periodontal changes in children and adolescents with diabetes: a case-control study. Diabetes Care 2006;29:295–9.10.2337/diacare.29.02.06.dc05-1355Search in Google Scholar PubMed
32. Goteiner D, Vogel R, Deasy M, Goteiner C. Periodontal and caries experience in children with insulin-dependent diabetes mellitus. J Am Dent Assoc 1986;113:277–9.10.14219/jada.archive.1986.0166Search in Google Scholar PubMed
33. Oral Health Education Unit, Department of Health. Hong Kong SAR. www.toothclub.gov.hk. Oral health survey: Chapter 4. 2011:63–96.Search in Google Scholar
34. Carranza FA, Newman MG. [Current concepts about dental plaque]. Rev Asoc Odontol Argent 1980;68:293–4.Search in Google Scholar PubMed
35. Bolgul BS, Celenk S, Ayna BE, Atakul F, Uysal E. Evaluation of caries risk factors and effects of a fluoride-releasing adhesive material in children with insulin-dependent diabetes mellitus (IDDM): initial first-year results. Acta Odontol Scand 2004;62:289–92.10.1080/00016350410001766Search in Google Scholar PubMed
©2017 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Frontmatter
- Mini Review
- Severe complications after initial management of hyperglycemic hyperosmolar syndrome and diabetic ketoacidosis with a standard diabetic ketoacidosis protocol
- Original Articles
- Markers influencing the presence of partial clinical remission in patients with newly diagnosed type 1 diabetes
- Oral health status of children with type 1 diabetes: a comparative study
- The relationship between non-alcoholic fatty liver disease and small intestinal bacterial overgrowth among overweight and obese children and adolescents
- High attainment of optimal nutritional and growth status observed among Greek pediatric cystic fibrosis patients: results from the GreeCF study
- Secular trends in height, weight and body mass index of primary school children in Turkey between 1993 and 2016
- Effects of 1-year growth hormone replacement therapy on thyroid volume and function of the children and adolescents with idiopathic growth hormone deficiency
- Thyroid hormone levels in late preterm, early term and term infants: a study with healthy neonates revealing reference values and factors affecting thyroid hormones
- Makorin ring finger 3 gene analysis in Koreans with familial precocious puberty
- Genetic analysis of fructose-1,6-bisphosphatase (FBPase) deficiency in nine consanguineous Pakistani families
- Reassessing the significance of the PAH c.158G>A (p.Arg53His) variant in patients with hyperphenylalaninemia
- Case Reports
- Sirolimus precipitating diabetes mellitus in a patient with congenital hyperinsulinaemic hypoglycaemia due to autosomal dominant ABCC8 mutation
- Persistent de Quervain tenosynovitis induced by somatotropin treatment
- Early-onset severe obesity due to complete deletion of the leptin gene in a boy
- Congenital cataract with LSS gene mutations: a new case report
Articles in the same Issue
- Frontmatter
- Mini Review
- Severe complications after initial management of hyperglycemic hyperosmolar syndrome and diabetic ketoacidosis with a standard diabetic ketoacidosis protocol
- Original Articles
- Markers influencing the presence of partial clinical remission in patients with newly diagnosed type 1 diabetes
- Oral health status of children with type 1 diabetes: a comparative study
- The relationship between non-alcoholic fatty liver disease and small intestinal bacterial overgrowth among overweight and obese children and adolescents
- High attainment of optimal nutritional and growth status observed among Greek pediatric cystic fibrosis patients: results from the GreeCF study
- Secular trends in height, weight and body mass index of primary school children in Turkey between 1993 and 2016
- Effects of 1-year growth hormone replacement therapy on thyroid volume and function of the children and adolescents with idiopathic growth hormone deficiency
- Thyroid hormone levels in late preterm, early term and term infants: a study with healthy neonates revealing reference values and factors affecting thyroid hormones
- Makorin ring finger 3 gene analysis in Koreans with familial precocious puberty
- Genetic analysis of fructose-1,6-bisphosphatase (FBPase) deficiency in nine consanguineous Pakistani families
- Reassessing the significance of the PAH c.158G>A (p.Arg53His) variant in patients with hyperphenylalaninemia
- Case Reports
- Sirolimus precipitating diabetes mellitus in a patient with congenital hyperinsulinaemic hypoglycaemia due to autosomal dominant ABCC8 mutation
- Persistent de Quervain tenosynovitis induced by somatotropin treatment
- Early-onset severe obesity due to complete deletion of the leptin gene in a boy
- Congenital cataract with LSS gene mutations: a new case report