Childhood parathyroid adenoma: a rare but important cause of nephrolithiasis
-
Prema Menon
,
Devi Dayal
Abstract
Primary hyperparathyroidism is very rare in children and adolescents. The management of a 12-year-old boy with renal calculi due to parathyroid adenoma is discussed. The single tumor after localization with sestamibi scintigraphy and SPECT-CT scan was excised with amelioration of symptoms. The case is reported due to the rarity of the disease and successful unilateral exploration. The association with hypopigmented areas of skin has also not been previously reported in literature.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: None declared.
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
References
1. Durkin ET, Nichol PF, Lund DP, Chen H, Sippel RS. What is the optimal treatment for children with primary hyperparathyroidism? J Ped Surg 2010;45:1142–6.10.1016/j.jpedsurg.2010.02.074Search in Google Scholar
2. Kollars J, Zarroug AE, van Heerden J, Lteif A, Stavlo P, et al. Primary hyperparathyroidism in pediatric patients. Pediatrics 2005;115:974–80.10.1542/peds.2004-0804Search in Google Scholar
3. Harman CR, van Heerden JA, Farley DR, Grant CS, Thompson GB, et al. Sporadic primary hyperparathyroidism in young patients: a separate entity? Arch Surg 1999;134:651–5.10.1001/archsurg.134.6.651Search in Google Scholar
4. Eklioglu BS, Atabek ME, Akyurek N. Parathyroid adenoma presented with multiple brown tumors and nephrocalcinosis. J Pediatr Endocrinol Metab 2013;26:213–4.10.1515/jpem-2012-0275Search in Google Scholar
5. Libansky P, Astl J, Adamek S, Nanka O, Pafko P, et al. Surgical treatment of primary hyperparathyroidism in children: report of 10 cases. Int J Pediatr Otorhinolaryngol 2008;72:1177–82.10.1016/j.ijporl.2008.04.005Search in Google Scholar
6. Sneider MS, Solorzano CC, Montano RE, Anello C, Irvin GL, et al. Sporadic primary hyperparathyroidism in young individuals different disease and treatment? J Surg Research 2009;155:100–3.10.1016/j.jss.2008.07.041Search in Google Scholar
7. Shah VN, Bhadada SK, Bhansali A, Behera A, Mittal BR, et al. Influence of age and gender on presentation of symptomatic primary hyperparathyroidism. J Postgrad Med 2012;58:107–11.10.4103/0022-3859.97171Search in Google Scholar
8. Fuleihan GE, Rubeiz N. Dermatological manifestations of parathyroid-related disorders. Clin Dermatol 2006;24:281–8.10.1016/j.clindermatol.2006.04.003Search in Google Scholar
9. Simsek E, Arikan Y, Dallar Y, Akkus MA. Prolonged hungry bone syndrome in a 10-year-old child with parathyroid adenoma. Indian Pediatr 2009;46:178–80.Search in Google Scholar
10. Profanter C, Wetscher GJ, Gabriel M, Sauper T, Rieger M, et al. CT-MIBI image fusion: a new preoperative localization technique for primary, recurrent, and persistent hyperparathyroidism. Surgery 2004;135:157–62.10.1016/S0039-6060(03)00396-9Search in Google Scholar
11. Mollerup CL, Lindewals H. Renal stones and primary hyperparathyroidism: natural history of renal stone disease after successful parathyroidectomy. World J Surg 1999;23:173–5.10.1007/PL00013175Search in Google Scholar
©2016 by De Gruyter
Articles in the same Issue
- Frontmatter
- Original Articles
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- Generic and disease-specific quality of life in adolescents with type 1 diabetes: comparison to age-matched healthy peers
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- Case Reports
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- Childhood parathyroid adenoma: a rare but important cause of nephrolithiasis
- A unique case of growth hormone and human chorionic gonadotropin treatment in a 45,X male with Y: autosome translocation and literature review
- Propionic acidemia: a Turkish case report of a successful pregnancy, labor and lactation
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Articles in the same Issue
- Frontmatter
- Original Articles
- Translation and psychometric properties of the Persian version of self-management of type 1 diabetes for adolescents
- Generic and disease-specific quality of life in adolescents with type 1 diabetes: comparison to age-matched healthy peers
- Relationship between HOMA-IR and serum vitamin D in Chinese children and adolescents
- Low 25-hydroxyvitamin D level is not an independent risk factor for hepatosteatosis in obese children
- Pediatric thyroid nodules: ultrasonographic characteristics and inter-observer variability in prediction of malignancy
- Frequency of thyroid status monitoring in the first year of life and predictors for more frequent monitoring in infants with congenital hypothyroidism
- Biochemical, radiological, and genetic characterization of congenital hypothyroidism in Abu Dhabi, United Arab Emirates
- High prevalence of DUOX2 mutations in Japanese patients with permanent congenital hypothyroidism or transient hypothyroidism
- Children with severe Osteogenesis imperfecta and short stature present on average with normal IGF-I and IGFBP-3 levels
- Association between physical activity and bone in children with Prader-Willi syndrome
- CNDP1 genotype and renal survival in pediatric nephropathies
- 17-Hydroxyprogesterone responses to human chorionic gonadotropin are not associated with serum anti-Mullerian hormone levels among adolescent girls with polycystic ovary syndrome
- Near-final height in 82 Chinese patients with congenital adrenal hyperplasia due to classic 21-hydroxylase deficiency: a single-center study from China
- Case Reports
- Sertoli cell only syndrome with ambiguous genitalia
- Childhood parathyroid adenoma: a rare but important cause of nephrolithiasis
- A unique case of growth hormone and human chorionic gonadotropin treatment in a 45,X male with Y: autosome translocation and literature review
- Propionic acidemia: a Turkish case report of a successful pregnancy, labor and lactation
- Unusual phenotype of congenital adrenal hyperplasia (CAH) with a novel mutation of the CYP21A2 gene
- Central diabetes insipidus as a very late relapse limited to the pituitary stalk in Langerhans cell histiocytosis
