Abstract
Triphala is a combination of three herbs amla, bahera and haritaki, it is widely available in the form churna and is a valued formula since ancient times. The aim of this research was to develop reproducible batches of triphala tablets and evaluation of the optimized batch. Direct compression was the method of choice. The tablets were prepared using different directly compressible excipients MicroceLac, Ludipress, Ludiflash. High Performance Liquid Chromatography (HPLC) method was employed for authentification of the herbs using gallic acid as the marker. The tablets were evaluated as per the pharmacopoeial tests. The tablets each weighing 600 mg were successfully formulated fulfilling the limits of evaluation.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: None declared.
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report or in the decision to submit the report for publication.
References
1. Alok S, Shanker C, Lalit K, Mahendra S, Rao C. Herbal medicine for market potential in India: an overview. Acad J Plant Sci. 2008;1:26–36.Suche in Google Scholar
2. Gowda V, Ganesh M, Rangesh R, Rohan D. Phytochemical and pharmacological actions of triphala: ayurvedic formulation – a review. Int J Pharm Sci. 2012;15:61–65.Suche in Google Scholar
3. Bali C, Ramesh Chandra K, Mita K, Ramamurthy A, Sumit N. Triphala: A comprehensive ayurvedic review. Int Res Ayu Pharm. 2013;4:612–617.10.7897/2277-4343.04433Suche in Google Scholar
4. Gowtham K, Pallavi C. Direct compression – an overview. Int J Res Pharm Biomed Sci. 2013;4:155–158.Suche in Google Scholar
5. Indian Pharmacopoeia. The Indian Pharmacopoeia Commission, 2007:178–184. Vol. 3.Suche in Google Scholar
6. The Ayurvedic Pharmacopoeia of India. Government of India, Ministry of Health and Family Welfare, 2012 01(01)4,5&47.Suche in Google Scholar
7. Aulton M. Pharmaceutics: The science of dosage form design Vol. 02. London: Churchill Livingstone, 2002:21–46.Suche in Google Scholar
8. Lachman L, Liebermann H. The theory and practice of industrial pharmacy. New Delhi: CBS Publishers and Distributors Pvt. Ltd. Special Indian Ed 2009:239–345.Suche in Google Scholar
© 2017 Walter de Gruyter GmbH, Berlin/Boston
Artikel in diesem Heft
- Review
- Ethnopharmacological approaches in mood and anxiety disorders. The relevance of the oxidative stress status
- Preclinical Studies
- Cytokine changes in gastric and colonic epithelial cell in response to Planta ovata extract
- Preliminary phytochemical analysis and evaluation of antioxidant, cytotoxic and inhibition of lipopolysaccaride - induced NOS (iNOS) expression in BALB/c mice liver by Ziziphus oenoplia Mill. fruit
- Evaluation of the sub-chronic toxicity profile of the corm of Xanthosoma sagittifolium on hematology and biochemistry of alloxan-induced diabetic Wistar rats
- Dendrobium chrysanthum ethanolic extract induces apoptosis via p53 up-regulation in HeLa cells and inhibits tumor progression in mice
- Safety assessment of the aqueous extract of the flowers of Nymphaea lotus Linn (Nymphaeaceae): Acute, neuro- and subchronic oral toxicity studies in albinos Wistar rats
- Effect of aqueous extract of Aegle marmelos fruit and leaf on glycemic, insulinemic and lipidemic status of type 2 diabetic model rats
- Antihypernociceptive and antioxidant effects of Petersianthus macrocarpus stem bark extracts in rats with complete Freund’s adjuvant-induced persistent inflammatory pain
- ROS-mediated induction of apoptosis by benzoquinone embelin in human colon adenocarcinoma cells HT-29
- Clinical Studies
- Desensitization to chemical and food sensitivities by low-dose immunotherapy ascertained by provocation neutralization is associated with reduced influx of calcium ions into lymphocytes
- Managing irritable bowel syndrome: The impact of micro-physiotherapy
- Short Communication
- Design development and evaluation of triphala tablets
Artikel in diesem Heft
- Review
- Ethnopharmacological approaches in mood and anxiety disorders. The relevance of the oxidative stress status
- Preclinical Studies
- Cytokine changes in gastric and colonic epithelial cell in response to Planta ovata extract
- Preliminary phytochemical analysis and evaluation of antioxidant, cytotoxic and inhibition of lipopolysaccaride - induced NOS (iNOS) expression in BALB/c mice liver by Ziziphus oenoplia Mill. fruit
- Evaluation of the sub-chronic toxicity profile of the corm of Xanthosoma sagittifolium on hematology and biochemistry of alloxan-induced diabetic Wistar rats
- Dendrobium chrysanthum ethanolic extract induces apoptosis via p53 up-regulation in HeLa cells and inhibits tumor progression in mice
- Safety assessment of the aqueous extract of the flowers of Nymphaea lotus Linn (Nymphaeaceae): Acute, neuro- and subchronic oral toxicity studies in albinos Wistar rats
- Effect of aqueous extract of Aegle marmelos fruit and leaf on glycemic, insulinemic and lipidemic status of type 2 diabetic model rats
- Antihypernociceptive and antioxidant effects of Petersianthus macrocarpus stem bark extracts in rats with complete Freund’s adjuvant-induced persistent inflammatory pain
- ROS-mediated induction of apoptosis by benzoquinone embelin in human colon adenocarcinoma cells HT-29
- Clinical Studies
- Desensitization to chemical and food sensitivities by low-dose immunotherapy ascertained by provocation neutralization is associated with reduced influx of calcium ions into lymphocytes
- Managing irritable bowel syndrome: The impact of micro-physiotherapy
- Short Communication
- Design development and evaluation of triphala tablets