Antibacterial activity of combination of synthetic and biopolymer non-woven structures
-
Sukhwinder K. Bhullar
,
Burcak Kaya Özsel
Abstract
Background: Fibrous structures and synthetic polymer blends offer potential usages in making biomedical devices, textiles used in medical practices, food packaging, tissue engineering, environmental applications and biomedical arena. These products are also excellent candidates for building scaffolds to grow stem cells for implantation, to make tissue engineering grafts, to make stents to open up blood vessels caused by atherosclerosis or narrowed by blood clots, for drug delivery systems for micro- to nano-medicines, for transdermal patches, and for healing of wounds and burn care. The current study was designed to evaluate the antimicrobial activity of woven and non-woven forms of nano- and macro-scale blended polymers having biocompatible and biodegradable characteristics.
Methods: The antimicrobial activity of non-woven fibrous structures created with the combination of synthetic and biopolymer was assessed using Gram-negative, Gram-positive bacteria, such as Staphylococcus aureus, Proteus vulgaris, Escherichia coli and Enterobacter aerogenes using pour plate method. Structural evaluation of the fabricated samples was performed by Fourier transform infrared spectroscopy.
Results: Broad spectrum antibacterial activities were found from the tested materials consisting of polyvinyl alcohol (PVA) with chitosan and nylon-6 combined with chitosan and formic acid.
Conclusions: The combination of PVA with chitosan was more bactericidal or bacteriostatic than that of nylon-6 combined with chitosan and formic acid. PVA combination with chitosan appears to be a broad-spectrum antimicrobial agent.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: None declared.
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
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©2015 by De Gruyter
Artikel in diesem Heft
- Frontmatter
- Review
- Experimental techniques for screening of antiosteoporotic activity in postmenopausal osteoporosis
- Preclinical Studies
- Immunomodulatory activity of methanol leaf extracts of Cameroonian medicinal plants
- Dietary supplementation with green tea extract promotes enhanced human leukocyte activity
- Newtonoate as an active principle of Newtonia griffoniana for anxiolytic activity in Swiss mice
- Antibacterial activity of combination of synthetic and biopolymer non-woven structures
- Amelioration of chronic inflammation and oxidative stress indices in diabetic Wistar rats using methanol leaf extract of Bridelia micrantha (Hochst) Baill. (Euphorbiaceae)
- Possible anti-diarrhoeal potential of ethanol leaf extract of Chromolaena odorata in castor oil-induced rats
- Inhibition of AKT signaling by supercritical CO2 extract of mango ginger (Curcuma amada Roxb.) in human glioblastoma cells
- Clinical Studies
- A cross-sectional study on knowledge and attitude toward Traditional Chinese Medicine (TCM) among adults in selected regions of Malaysia
- Assessment of the impacts of traditional Persian medical schemes and recommendations on functional chronic constipation compared to a classic medicine lactulose, a randomized clinical trial
Artikel in diesem Heft
- Frontmatter
- Review
- Experimental techniques for screening of antiosteoporotic activity in postmenopausal osteoporosis
- Preclinical Studies
- Immunomodulatory activity of methanol leaf extracts of Cameroonian medicinal plants
- Dietary supplementation with green tea extract promotes enhanced human leukocyte activity
- Newtonoate as an active principle of Newtonia griffoniana for anxiolytic activity in Swiss mice
- Antibacterial activity of combination of synthetic and biopolymer non-woven structures
- Amelioration of chronic inflammation and oxidative stress indices in diabetic Wistar rats using methanol leaf extract of Bridelia micrantha (Hochst) Baill. (Euphorbiaceae)
- Possible anti-diarrhoeal potential of ethanol leaf extract of Chromolaena odorata in castor oil-induced rats
- Inhibition of AKT signaling by supercritical CO2 extract of mango ginger (Curcuma amada Roxb.) in human glioblastoma cells
- Clinical Studies
- A cross-sectional study on knowledge and attitude toward Traditional Chinese Medicine (TCM) among adults in selected regions of Malaysia
- Assessment of the impacts of traditional Persian medical schemes and recommendations on functional chronic constipation compared to a classic medicine lactulose, a randomized clinical trial
