Comparative effects of Orchis anatolica vs. the red Korean Panax ginseng treatments on testicular structure and function of adult male mice
Abstract
Background: The effects of Orchis anatolica plant roots on adult male mice testicular structure and function were explored and compared with those of the red Korean Panax ginseng.
Methods: Both plants were administered orally to two separate mice groups at a dose of 800 mg/kg/day for 35 days and compared with control group. After treatment, 5 mice of each group were sacrificed and total mice weights, reproductive organs’ weights, spermatogenesis, and androgenic serum markers were investigated. The remaining mice from all groups were allowed to mate with virgin female mice to explore male fertility potential.
Results: Results indicated that body and organs’ weights were increased significantly in mice treated with Orchis anatolica where only slight changes were observed in red Korean Panax ginseng treated and control mice. Intestinal testicular Leydig cells and germinal cells counts were elevated significantly in mice treated with Orchis anatolica plant when compared with the other two groups. Testicular dynamics parameters recorded in both testes and caudae epididymides were found to be increased only in Orchis anatolica treated mice. Although testosterone serum titer was observed to be elevated in both treated mice groups a marked elevation was observed only in Orchis anatolica treated mice. Follicular stimulating hormone blood serum titer was also elevated obtained in Orchis anatolica treated mice when compared with the other two groups. The fertility index of male mice treated with Orchis anatolica plant was enhanced to a greater value when allowed mating with virgin female mice if compared with male mice fertility index recorded in the other two groups.
Conclusions: We can conclude that Orchis anatolica plant could be more useful to improve testicular functions and structural parameters in mice when compared with red Korean Panax ginseng.
References
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©2015 by De Gruyter
Artikel in diesem Heft
- Frontmatter
- Review
- An emphasis on molecular mechanisms of anti-inflammatory effects and glucocorticoid resistance
- Preclinical Studies
- Endothelium nitric oxide-independent vasorelaxant effects of the aqueous extract from Stephania abyssinica on the isolated rat thoracic aorta
- Evidence of attenuation of intestinal ischemia–reperfusion injury following pre-treatment with methanolic extracts from Chromolena odorata in rats
- Comparative effects of Orchis anatolica vs. the red Korean Panax ginseng treatments on testicular structure and function of adult male mice
- The Miaoyao Fanggan Sachets regulate humoral immunity and cellular immunity in mice
- Toxicological evaluation of the aqueous extract of Acalypha wilkesiana in Wistar albino rats
- Clinical Studies
- Tolerability of the combination of ginger (Zingiber officinalis), gentian (Gentiana lutea) and turmeric (Curcuma longa) in patients with cancer-associated anorexia
- Effect of rhubarb (Rheum emodi) in primary dysmenorrhoea: a single-blind randomized controlled trial
- Integrating traditional medical practice with primary healthcare system in Eritrea
- Factors affecting the use of complementary and alternative medicine among Japanese university students
- Short Communication
- Complementary and alternative medicine in diabetes (CALMIND) – a prospective study
- Online Only: Congress Abstracts
- 2014 IN-CAM Research Symposium: The Next Wave of Complementary and Integrative Medicine and Health Care Research
Artikel in diesem Heft
- Frontmatter
- Review
- An emphasis on molecular mechanisms of anti-inflammatory effects and glucocorticoid resistance
- Preclinical Studies
- Endothelium nitric oxide-independent vasorelaxant effects of the aqueous extract from Stephania abyssinica on the isolated rat thoracic aorta
- Evidence of attenuation of intestinal ischemia–reperfusion injury following pre-treatment with methanolic extracts from Chromolena odorata in rats
- Comparative effects of Orchis anatolica vs. the red Korean Panax ginseng treatments on testicular structure and function of adult male mice
- The Miaoyao Fanggan Sachets regulate humoral immunity and cellular immunity in mice
- Toxicological evaluation of the aqueous extract of Acalypha wilkesiana in Wistar albino rats
- Clinical Studies
- Tolerability of the combination of ginger (Zingiber officinalis), gentian (Gentiana lutea) and turmeric (Curcuma longa) in patients with cancer-associated anorexia
- Effect of rhubarb (Rheum emodi) in primary dysmenorrhoea: a single-blind randomized controlled trial
- Integrating traditional medical practice with primary healthcare system in Eritrea
- Factors affecting the use of complementary and alternative medicine among Japanese university students
- Short Communication
- Complementary and alternative medicine in diabetes (CALMIND) – a prospective study
- Online Only: Congress Abstracts
- 2014 IN-CAM Research Symposium: The Next Wave of Complementary and Integrative Medicine and Health Care Research