Melatonin ameliorates some biochemical alterations following ketoconazole administration in rats

References

[1] Kinobe RT, Dercho RA, Vlahakis JZ, Brien JF, Szarek WA, Nakatsu K. Inhibition of the enzymatic activity of heme oxygenases by azole-based antifungal drugs. J Pharmacol Exp Ther 2006;319:277–84.10.1124/jpet.106.102699Search in Google Scholar

[2] Rodriguez RJ, Proteau PJ, Marquez BL, Hetherington CL, Buckholz CJ, O’Connell KL. Flavin-containing monooxygenase-mediated metabolism of N-deacetyl ketoconazole by rat hepatic microsomes. Drug Metabol 1999;27:880–6.Search in Google Scholar

[3] Majagi SI, Khan MD, Patil PA. Anti-inflammatory and analgesic activity of ketoconazole and miconazole in Wistar rats. J Pharm Res 2011;4:714–6.Search in Google Scholar

[4] Iamsaard S, Burawat J, Kanla P, Arun S, Sukhorum W, Sripanidkulchai B, et al. Antioxidant activity and protective effect of Clitoria ternatea flower extract on testicular damage induced by ketoconazole in rats. J Zhejiang Univ Sci B 2014;15:548–55.10.1631/jzus.B1300299Search in Google Scholar

[5] Santen RJ, Bossche HV, Symoens J, Brugmans J, DeCoster R. Site of action of low dose ketoconazole on androgen biosynthesis in men. J Clin Endocrinol Metabol 1983;57:732–6.10.1210/jcem-57-4-732Search in Google Scholar

[6] Adams ML, Meyer E, Cicero TJ. Imidazoles suppress rat testosterone secretion and testicular interstitial fluid formation in vivo. Biol Reprod 1998;59:248–54.10.1095/biolreprod59.2.248Search in Google Scholar

[7] Amin A. Ketoconazole-induced testicular damage in rats reduced by Gentiana extract. Exp Toxicol Pathol 2008;59:377–84.10.1016/j.etp.2007.10.008Search in Google Scholar

[8] Paroni R, Terraneo L, Bonomini F, Finati E, Virgili E, Bianciardi P, et al. Antitumour activity of melatonin in a mouse model of human prostate cancer: relationship with hypoxia signaling. J Pineal Res 2014;57:43–52.10.1111/jpi.12142Search in Google Scholar

[9] Alibek K, Mektepbayeva D, Irving S, Atinbayeva N, Zhaisanbayeva B, Mussurova S, et al. Anticancer effects and uses of melatonin: a review. Austin J Cancer Clin Res 2015;2:1052.Search in Google Scholar

[10] Kilinçel Ö, Çaliskan E, Sahin I, Öztürk CE, Kiliç N, Öksüz S. The effect of melatonin on antifungal susceptibility in planktonic and biofilm forms of Candida strains isolated from clinical samples. Med Mycol 2019;57:45–51.10.1093/mmy/myx157Search in Google Scholar

[11] Mohammad GF, Faghani M, Khajeh JS, Bahadori M, Nasiri E, Hemadi M. Effect of melatonin on proliferative activity and optosis in spermatogenic cells in mouse under chemotherapy. J Reprod Contraception 2010;1:79–94.10.1016/S1001-7844(10)60016-8Search in Google Scholar

[12] Frungieri MB, Mayerhofer A, Zitta K, Pignataro OP, Calandra RS, Gonzalez-Calvar SI. Direct effect of melatonin on Syrian hamster testes: Mel1a receptors, inhibition of androgen production, and interaction with the local corticotropin-releasing hormone (CRH) system. Endocrinology 2005;146:1541–52.10.1210/en.2004-0990Search in Google Scholar

[13] Armagan A, Uz E, Yilmaz HR, Soyupek S, Oksay T, Ozcelik N. Effects of melatonin on lipid peroxidation and antioxidant enzymes in streptozotocin-induced diabetic rat testis. Asian J Androl 2006;8:595–600.10.1111/j.1745-7262.2006.00177.xSearch in Google Scholar

[14] Dubocovich ML, Markowska M. Functional MT1 and MT2 melatonin receptors in mammals. Endocrine 2005;27:101–10.10.1385/ENDO:27:2:101Search in Google Scholar

[15] Galano A, Tan DX, Reiter RJ. Melatonin as a natural ally against oxidative stress: a physicochemical examination. J Pineal Res 2011;51:1–16.10.1111/j.1600-079X.2011.00916.xSearch in Google Scholar

[16] Allegra M, Reiter RJ, Tan DX, Gentile C, Tesoriere L, Livrea MA. The chemistry of melatonin interaction with reactive species. J Pineal Res 2003;34:1–10.10.1034/j.1600-079X.2003.02112.xSearch in Google Scholar

[17] Tomas-Zapico C, Coto-Montes A. A proposed mechanism to explain the stimulatory effect of melatonin on anti-oxidative enzymes. J Pineal Res 2005;39:99–104.10.1111/j.1600-079X.2005.00248.xSearch in Google Scholar

[18] Rodrıguez MI, Escames G, López LC, López A, García JA, Ortiz F, et al. Chronic melatonin treatment reduces the age-dependent inflammatory process in senescence-accelerated mice. J Pineal Res 2007;42:272–9.10.1111/j.1600-079X.2006.00416.xSearch in Google Scholar

[19] Esquifino A, Agrasal C, Velkzquez E, Villantia MA, Cardinali DP. Effect of melatonin on serum cholesterol and phospholipid levels, and on prolactin, thyroid-stimulating hormone and thyroid hormone levels, in hyperprolactinemic rats. Life Sci 1997;61:1051–8.10.1016/S0024-3205(97)00613-9Search in Google Scholar

[20] National Academy of Sciences. Guide for the care and use of laboratory animals. Washington, DC: National Academies Press, 2011.Search in Google Scholar

[21] Heckman WR, Kane BR, Pakyz RE, Cosentino MJ. The effect of ketoconazole on endocrine and reproductive parameters in male mice and rats. J Androl 1992;13:191–8.10.1002/j.1939-4640.1992.tb00298.xSearch in Google Scholar

[22] Olayaki LA, Alagbonsi AI, Amin H, Adeyemi WJ, Bakare M, Noah O. Melatonin prevents and ameliorates lead-induced gonadotoxicity through anti-oxidative and hormonal mechanisms. Toxicol Ind Health 2018;34:596–608.10.1177/0748233718773508Search in Google Scholar PubMed

[23] Tapazoglou E, Subramanian MG, Al-Sarraf M, Kresge C, Decker DA. High-dose ketoconazole therapy in patients with metastatic prostate cancer. Am J Clin Oncol 1986;9:369–75.10.1097/00000421-198610000-00001Search in Google Scholar PubMed

[24] Trump DL, Havlin KH, Messing EM, Cummings KB, Lange PH, Jordan VC. High-dose ketoconazole in advanced hormone-refractory prostate cancer: endocrinologic and clinical effects. J Clin Oncol 1989;7:1093–8.10.1200/JCO.1989.7.8.1093Search in Google Scholar PubMed

[25] Reagan-Shaw S, Nihal M, Ahmad N. Dose translation from animal to human studies revisited. FASEB J 2007;22:659–61.10.1096/fj.07-9574LSFSearch in Google Scholar PubMed

[26] Adeyemi WJ, Olayaki LA. Effects of single or combined induction of diabetes mellitus and knee osteoarthritis on some biochemical and haematological parameters in rats. Exp Mol Pathol 2017;103:113–20.10.1016/j.yexmp.2017.07.005Search in Google Scholar PubMed

[27] Adeyemi WJ, Olayaki LA. Calcitonin and omega-3 fatty acids exhibit antagonistic and non-additive effects in experimental diabetes. Pathophysioloy 2018;25:117–23.10.1016/j.pathophys.2018.02.003Search in Google Scholar

[28] Adeyemi WJ, Olayaki LA. Effects of salmon calcitonin and omega-3 fatty acids on selected biomarkers in experimental diabetic-osteoarthritic rats. Synergy 2019;8:100045.10.1016/j.synres.2018.100045Search in Google Scholar

[29] Afolabi AO, Aluko O, Oyewopo O, Olabinrin BM, Olotu O, Raji Y. Trino IB ameliorates the oxidative stress of cryptorchidism in rat. Afr J Biotechnol 2009;8:1183–7.Search in Google Scholar

[30] Quill AT, Garbers LD. Sperm motility activation and chemoattraction. In: Hardy DM, editor. Fertilization. San Diego, CA: Academic Press, 2002:29.10.1016/B978-012311629-1/50004-8Search in Google Scholar

[31] Darszon A, Labarca P, Nishigaki T, Espinosa F. Ion channels in sperm physiology. Physiol Rev 1999;79:481–510.10.1152/physrev.1999.79.2.481Search in Google Scholar

[32] Marwaha RK, Maheshwari A. Systemic antifungal therapy in pediatric practice. Indian Pediatr 1999;36:1011–21.Search in Google Scholar

[33] Pon A. Long-term experience with high-dose ketoconazole therapy in patients with stage D2 prostatic carcinoma. J Urol 1987;137:902–4.10.1016/S0022-5347(17)44290-XSearch in Google Scholar

[34] Buvat J. Hyperprolactinemia and sexual function in men: a short review. Int J Impot Res 2003;15:373–7.10.1038/sj.ijir.3901043Search in Google Scholar

[35] Masud S, Mehboob F, Bappi MU. Severe hyperprolactinemia directly depresses the gonadal activity causing infertility. Esculapio J Services Inst Med Sci 2007;2:25–7.Search in Google Scholar

[36] Wu YH, Zhou JN, Balesar R, Unmehopa U, Bao A, Jockers R, et al. Distribution of MT1 melatonin receptor immunoreactivity in the human hypothalamus and pituitary gland: colocalization of MT1 with vasopressin, oxytocin, and corticotropin-releasing hormone. J Comp Neurol 2006;499:897–910.10.1002/cne.21152Search in Google Scholar

[37] Reiter RJ. Pineal melatonin: cell biology of its synthesis and of its physiological interactions. Endocr Rev 1991;12:151–80.10.1210/edrv-12-2-151Search in Google Scholar

[38] Vanecek J, Pavlik A, Illnerova H. Hypothalamic melatonin receptor sites revealed by autoradiography. Brain Res 1987;435:359–62.10.1016/0006-8993(87)91625-8Search in Google Scholar

[39] Aitken RJ. The Amoroso lecture. The human spermatozoon – a cell in crisis? J Reprod Fertil 1999;115:1–7.10.1530/jrf.0.1150001Search in Google Scholar PubMed

[40] Lewis S, Aitken R. DNA damage to spermatozoa has impacts on fertilization and pregnancy. Cell Tissue Res 2005;322:33–41.10.1007/s00441-005-1097-5Search in Google Scholar

[41] Agarwal A, Makker K, Sharma R. Clinical relevance of oxidative stress in male factor infertility: an update. Am J Reprod Immunol 2008;59:2–11.10.1111/j.1600-0897.2007.00559.xSearch in Google Scholar

[42] Brown JE, Cook RJ, Lipton A, Coleman RE. Serum lactate dehydrogenase is prognostic for survival in patients with bone metastases from breast cancer: a retrospective analysis in bisphosphonate-treated patients. Clin Cancer Res 2012;18:6348–55.10.1158/1078-0432.CCR-12-1397Search in Google Scholar

[43] Adeyemi WJ, Olayaki LA. Synergistic and non-synergistic effects of salmon calcitonin and omega-3 fatty acids on antioxidant, anti-inflammatory, and haematological markers in diabetic rats. Biomed Pharmacother 2018;99:867–75.10.1016/j.biopha.2018.01.085Search in Google Scholar

[44] Adeyemi WJ, Olayaki LA. Diabetes escalates knee osteoarthritis in rats: evidence of adaptive mechanism. Environ Toxicol Pharmacol 2018;61:1–7.10.1016/j.etap.2018.05.009Search in Google Scholar

[45] Adeyemi WJ, Omoniyi AJ, Olayiwola A, Ibrahim M, Ogunyemi O, Olayaki LA. Elevated reproductive toxicity effect of diclofenac after withdrawal: investigation of the therapeutic role of melatonin. Toxicol Rep 2019;6:571–7.10.1016/j.toxrep.2019.06.009Search in Google Scholar

[46] Zhang HM, Zhang Y. Melatonin: a well-documented antioxidant with conditional pro-oxidant actions. J Pineal Res 2014;57:131–46.10.1111/jpi.12162Search in Google Scholar

[47] Poeggeler B, Reiter RJ, Hardeland R, Tan DX, Barlow-Walden LR. Melatonin and structurally related, endogenous indoles act as potent electron donors and radical scavengers in vitro. Redox Rep 1996;2:179–84.10.1080/13510002.1996.11747046Search in Google Scholar

[48] Mahal HS, Sharma HS, Mukerjee T. Antioxidant properties of melatonin: a pulse radiolysis study. Free Radic Biol Med 1999;26:557–65.10.1016/S0891-5849(98)00226-3Search in Google Scholar

[49] Haddad JJ. Oxygen-sensitive pro-inflammatory cytokines, apoptosis signaling and redox-responsive transcription factors in development and pathophysiology. Cytokines Cell Mol Ther 2002;7:1–14.10.1080/13684730216401Search in Google Scholar PubMed

[50] Ige SF, Akhigbe R, Olaleye B, Adeyemi W. Gastroprotective potentials of the methanolic extract of Garcinia kola in rats. Int J Med Biomed Res 2012;1:172–8.10.14194/ijmbr.133Search in Google Scholar

[51] Adeniyi MJ, Ige SF, Adeyemi WJ, Oni TJ, Ajayi PO, Odelola SO. Changes in body temperature and intestinal antioxidant enzymes in healthy and colitis male rats: role of Garcinia kola. Int J Physiol 2016;4:36–41.10.5958/2320-608X.2016.00046.9Search in Google Scholar

[52] Adeyemi WJ, Olayaki LA. Additive and non-additive effects of salmon calcitonin and omega-3 fatty acids on antioxidant, haematological and bone and cartilage markers in experimental diabetic-osteoarthritic rats. Chin J Physiol 2019;62:108–16.10.4103/CJP.CJP_8_18Search in Google Scholar PubMed

[53] Favero G, Franceschetti L, Bonomini F, Rodella LF, Rezzani R. Melatonin as an anti-inflammatory agent modulating inflammasome activation. Int J Endocrinol 2017;2017:1835195.10.1155/2017/1835195Search in Google Scholar PubMed PubMed Central