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Mathematical analysis of the impact of vaccination and poor sanitation on the dynamics of poliomyelitis

  • Christopher S. Bornaa ORCID logo EMAIL logo , Baba Seidu ORCID logo and Oluwole D. Makinde
Published/Copyright: April 26, 2021

Abstract

A deterministic model is developed to study the dynamics of poliomyelitis virus infection with vaccination in a population with insanitary conditions. The polio-free equilibrium is shown to be locally asymptotically stable whenever the basic reproduction number is less than one but global stability requires other conditions to be satisfied. The spread of the disease is also shown to be sensitive to the average contact rate with the faecal matter of the infectious individuals, the transmission probability, natural death rate and vaccination, probabilities of the exposed individuals progressing to the non-paralytic and paralytic classes, the open defecation parameter and the polio-induced death rate. Other interesting results are illustrated through numerical simulation of the model.

2010 MSC: 92D30; 34D20; 37N25; 92B05; 92D25

Corresponding author: Christopher S. Bornaa, Department of Science and Mathematics Education, C. K. Tadem University of Technology and Applied Sciences, Navrongo, Ghana 0215-5321, UK, E-mail:

  1. Author contribution: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Conflict of interest statement: The authors declare no conflicts of interest regarding this article.

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Received: 2020-07-07
Revised: 2021-02-28
Accepted: 2021-04-12
Published Online: 2021-04-26
Published in Print: 2023-02-23

© 2021 Walter de Gruyter GmbH, Berlin/Boston

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