Isolation of Linoleic Acid from Sambucus williamsii Seed Oil Extracted by High Pressure Fluid and Its Antioxidant, Antiglycemic, Hypolipidemic Activities
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Hui Lv
und
Kehai Liu
Abstract
Linoleic acid was isolated effectively from Sambucus williamsii (SW) seed oil which was extracted by high-pressure fluid and its biological activities were investigated. Linoleic acid was isolated from the oil by urea inclusion, the yield was 65.81% and the purity was 92.12%. 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay was used to determine the antioxidant activity of linoleic acid. IC50 of DPPH radical scavenging activity of linoleic acid was 61.92 mg/mL. The antiglycemic activity of linoleic acid was evaluated by determining its inhibitory effect on α-glucosidase. The results showed that α-glucosidase was inhibited to a certain extent by linoleic acid (1.56–25 mg/mL). In addition, the hypolipidemic activity of linoleic acid was investigated in vivo using hyperlipidemia mice models fed with the linoleic acid at doses of 1, 2, 4 g/kg BW (body weight). The results showed that serum lipid levels were highly significantly (p<0.01) improved, which indicated the hypolipidemic activity of linoleic acid. The linoleic acid extracted from SW seed oil was proved to possess good antioxidant, antiglycemic and hypolipidemic activity in human diets, which may have industrial use.
Acknowledgment
The authors wish to thank the Dean, College of Food Science and Technology, Shanghai Ocean University, Shanghai, China for having provided necessary support for carrying out this work.
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Artikel in diesem Heft
- Frontmatter
- Soft Tofu-Type Gels: Relationship between Volatile Compounds and Sensory Characteristics as Affected by Coagulants and Raw Materials
- Preparation and Characterization of Genipin-Crosslinked Chitosan Microspheres for the Sustained Release of Salidroside
- A Numerical Approach to Determine Some Properties of Cylindrical Pieces of Bananas During Drying
- Pasting, Textural and Sensory Characteristics of the Kofter, A Fruit-Based Dessert: Effect of Molasses and Water Concentration
- Microwave-Assisted Extraction of Phenolic Compounds from Dried Waste Grape Skins
- Effect of Cooking Temperature on Mineral Content and Anti-nutritional Factors of Yam and Taro Grown in Southern Ethiopia
- Isolation of Linoleic Acid from Sambucus williamsii Seed Oil Extracted by High Pressure Fluid and Its Antioxidant, Antiglycemic, Hypolipidemic Activities
- Comparison of Artificial Neural Network and Response Surface Methodology Performance on Fermentation Parameters Optimization of Bioconversion of Cashew Apple Juice to Gluconic Acid
- Modeling the Total Residence Time in a Rotary Dryer
- Optimization of Spray Drying Process Parameters for Sweet Corn Enzymolysis Liquid
- Hot Air Drying Characteristics of Sukkari Date (Phoenix dactylifera L.) and Effects of Drying Condition on Fruit Color and Texture
- Effects of Air-Impingement Jet Drying on Drying Kinetics, Nutrient Retention and Rehydration Characteristics of Onion (Allium cepa) Slices
Artikel in diesem Heft
- Frontmatter
- Soft Tofu-Type Gels: Relationship between Volatile Compounds and Sensory Characteristics as Affected by Coagulants and Raw Materials
- Preparation and Characterization of Genipin-Crosslinked Chitosan Microspheres for the Sustained Release of Salidroside
- A Numerical Approach to Determine Some Properties of Cylindrical Pieces of Bananas During Drying
- Pasting, Textural and Sensory Characteristics of the Kofter, A Fruit-Based Dessert: Effect of Molasses and Water Concentration
- Microwave-Assisted Extraction of Phenolic Compounds from Dried Waste Grape Skins
- Effect of Cooking Temperature on Mineral Content and Anti-nutritional Factors of Yam and Taro Grown in Southern Ethiopia
- Isolation of Linoleic Acid from Sambucus williamsii Seed Oil Extracted by High Pressure Fluid and Its Antioxidant, Antiglycemic, Hypolipidemic Activities
- Comparison of Artificial Neural Network and Response Surface Methodology Performance on Fermentation Parameters Optimization of Bioconversion of Cashew Apple Juice to Gluconic Acid
- Modeling the Total Residence Time in a Rotary Dryer
- Optimization of Spray Drying Process Parameters for Sweet Corn Enzymolysis Liquid
- Hot Air Drying Characteristics of Sukkari Date (Phoenix dactylifera L.) and Effects of Drying Condition on Fruit Color and Texture
- Effects of Air-Impingement Jet Drying on Drying Kinetics, Nutrient Retention and Rehydration Characteristics of Onion (Allium cepa) Slices
