CFD simulation study of internal mixing and flow of a modified airlift bioreactor
-
Zeng Lingwei
,
Li Zhenpeng
Abstract
When the airlift bioreactor is applied to the field of industrial fermentation, there is a common problem of low mixing and flow efficiency due to its simple structure. In order to expand the application of airlift bioreactor in the field of industrial fermentation, a new type of airlift bioreactor with three-dimensional bumps in the draft tube has been designed to enhance the mixing and flow of gas-liquid two-phase in the reactor. In order to determine the specific influence of the three-dimensional bumps on the internal flow field of the reactor, and to provide technical reference for the improvement of the structure of the airlift bioreactor, in this paper, the CFD simulation of this type of bioreactor is carried out. Based on the Euler multiphase flow, the Realizable k-ε model was used to analyze the flow field of the reactor with average gas-liquid flow linear velocity and temperature as parameters. The results show that under certain conditions, the three-dimensional bumps inside the draft tube can effectively accelerate the gas-liquid two-phase flow and better promotes the mixing of pig manure fermentation broth and air.
Funding source: Guangxi Key Laboratory of Petrochemical Resources Processing and Process Intensification Technology
Award Identifier / Grant number: 2021Z004
Acknowledgments
This study is partially supported by the Director Fund of Guangxi Key Laboratory of Petrochemical Resource Processing and Process Intensification Technology, Guangxi University (grant number: 2021Z004). We would like to express our gratitude for their financial support, which has made this study possible.
-
Research ethics: Not applicable.
-
Author contributions: The authors have accepted responsibility for the entire content of this manuscript and approved its submission.
-
Competing interests: The authors state no conflict of interest.
-
Research funding: Guangxi Key Laboratory of Petrochemical Resource Processing and Process Intensification Technology, Guangxi University, grant number: 2021Z004.
-
Data availability: The raw data can be obtained on request from the corresponding author.
References
[1] J. Zhang, B. Wei, R. Wen, Y. Liu, Z. Wang, and Z. Wang, “Genetically modified sugarcane intercropping soybean impact on rhizosphere bacterial communities and co-occurrence patterns,” Front. Microbiol., vol. 12, pp. 742341, 2021. https://doi.org/10.3389/fmicb.2021.742341.Search in Google Scholar PubMed PubMed Central
[2] J. M. García, et al., “Chemical and histological characterization of internodes of sugarcane and energy-cane hybrids throughout plant development,” Ind. Crop. Prod., vol. 199, pp. 116739, 2023. https://doi.org/10.1016/j.indcrop.2023.116739.Search in Google Scholar
[3] J. Li, et al., “Biochemical fulvic acid modification for phosphate crystal inhibition in water and fertilizer integration,” Materials, vol. 15, pp. 1174, 2022. https://doi.org/10.3390/ma15031174.Search in Google Scholar PubMed PubMed Central
[4] F. Zhu, L. Zhang, X. Hu, J. Zhao, Z. Meng, and Y. Zheng, “Research and design of hybrid optimized backpropagation (BP) neural network PID algorithm for integrated water and fertilizer precision fertilization control system for field crops,” Agronomy, vol. 13, pp. 1423, 2023. https://doi.org/10.3390/agronomy13051423.Search in Google Scholar
[5] A. Anand, et al., “A critical aspect of bioreactor designing and its application for the generation of tissue engineered construct: emphasis on clinical translation of bioreactor,” Biotechnol. Bioprocess Eng., vol. 27, pp. 494–514, 2022. https://doi.org/10.1007/s12257-021-0128-8.Search in Google Scholar
[6] T. Maischberger, “Optimized process and bioreactor characterization,” Chem. Ing. Tech., vol. 91, pp. 1719–1723, 2019. https://doi.org/10.1002/cite.201900134.Search in Google Scholar
[7] T. Chuacharoen, S. Aroonsong, and T. Chysirichote, “Alginate production of Azotobacter vinelandii using sugar cane juice as the main carbon source in an airlift bioreactor,” Ind. Eng. Chem. Res., vol. 61, pp. 12329–12337, 2022. https://doi.org/10.1021/acs.iecr.2c02693.Search in Google Scholar
[8] T. Zhang, C. We, Y. Ren, C. Feng, and H. Wu, “Advances in airlift reactors: modified design and optimization of operation conditions,” Rev. Chem. Eng., vol. 33, pp. 163–182, 2017. https://doi.org/10.1515/revce-2016-0005.Search in Google Scholar
[9] S. H. Ammar and A. S. Akbar, “Oilfield produced water treatment in internal-loop airlift reactor using electrocoagulation/flotation technique,” Chin. J. Chem. Eng., vol. 26, pp. 879–885, 2018. https://doi.org/10.1016/j.cjche.2017.07.020.Search in Google Scholar
[10] F. Ramonet, B. Haddadi, and M. Harasek, “Optimal design of double stage internal loop air-lift bioreactor,” Energies, vol. 16, pp. 3267, 2023. https://doi.org/10.3390/en16073267.Search in Google Scholar
[11] J. Glas, S. Drandev, V. Pupkevich, and D. Karamanev, “Energy balance of an airlift bioreactor used for electrical power generation in energy storage,” Chem. Eng. Sci., vol. 210, pp. 115208, 2019. https://doi.org/10.1016/j.ces.2019.115208.Search in Google Scholar
[12] M. K. H. Al-Mashhadani, S. J. Wilkinson, and W. B. Zimmerman, “Airlift bioreactor for biological applications with microbubble mediated transport processes,” Chem. Eng. Sci., vol. 137, pp. 243–253, 2015. https://doi.org/10.1016/j.ces.2015.06.032.Search in Google Scholar
[13] S. Seidel, R. W. Maschke, S. Werner, V. Jossen, and D. Eibl, “Oxygen mass transfer in biopharmaceutical processes: numerical and experimental approaches,” Chem. Ing. Tech., vol. 93, pp. 42–61, 2021. https://doi.org/10.1002/cite.202000179.Search in Google Scholar
[14] R. Särkelä, T. Eerikäinen, J. Pitkänen, and S. Bankar, “Mixing efficiency studies in an airlift bioreactor with helical flow promoters for improved reactor performance,” Chem. Eng. Process. Process Intensif., vol. 137, pp. 80–86, 2019. https://doi.org/10.1016/j.cep.2019.02.006.Search in Google Scholar
[15] D. Xue, D. Yao, R. K. Sukumaran, X. You, Z. Wei, and C. Gong, “Tandem integration of aerobic fungal cellulase production, lignocellulose substrate saccharification and anaerobic ethanol fermentation by a modified gas lift bioreactor,” Bioresour. Technol., vol. 302, pp. 122902, 2020. https://doi.org/10.1016/j.biortech.2020.122902.Search in Google Scholar PubMed
[16] M. Räsänen, T. Eerikäinen, and H. Ojamo, “Characterization and hydrodynamics of a novel helix airlift reactor,” Chem. Eng. Process. Process Intensif., vol. 108, pp. 44–57, 2016. https://doi.org/10.1016/j.cep.2016.07.006.Search in Google Scholar
[17] X. Li, et al., “Power-saving airlift bioreactor with helical sieve plates: Developmental and performance studies,” Chem. Eng. Res. Des., vol. 158, pp. 1–11, 2020. https://doi.org/10.1016/j.cherd.2020.03.014.Search in Google Scholar
[18] R. Askari and M. R. Soltani, “Effects of mach number on the performance of a diverterless supersonic inlet,” J. Aircr., vol. 56, pp. 1697–1707, 2019. https://doi.org/10.2514/1.c035328.Search in Google Scholar
[19] R. Askari, M. R. Soltani, K. Mostoufi, A. Khajeh Fard, and M. Abedi, “Angle of attack investigations on the performance of a diverterless supersonic inlet,” J. Appl. Fluid Mech., vol. 12, pp. 2017–2030, 2019. https://doi.org/10.29252/jafm.12.06.29880.Search in Google Scholar
[20] 曾令威, 李振鹏, 滕家皇与陆水等, 畜禽废弃物制作植物水肥的装置及其方法. CN116410026A, 2023.Search in Google Scholar
[21] O. Popoola and Y. Cao, “The influence of turbulence models on the accuracy of CFD analysis of a reciprocating mechanism driven heat loop,” Case Stud. Therm. Eng., vol. 8, pp. 277–290, 2016. https://doi.org/10.1016/j.csite.2016.08.009.Search in Google Scholar
[22] P. Krýsa and M. Šoóš, “Modelling of bubble breakage and coalescence in stirred and sparged bioreactor using the Euler-Lagrange approach,” Int. J. Heat Mass Transf., vol. 199, pp. 123466, 2022. https://doi.org/10.1016/j.ijheatmasstransfer.2022.123466.Search in Google Scholar
[23] H. Lyu, D. Lucas, R. Rzehak, and F. Schlegel, “A particle-center-averaged Euler-Euler model for monodisperse bubbly flows,” Chem. Eng. Sci., vol. 260, pp. 117943, 2022. https://doi.org/10.1016/j.ces.2022.117943.Search in Google Scholar
[24] V. Jossen, R. Eibl, M. Kraume, and D. Eibl, “Growth behavior of human adipose tissue-derived stromal/stem cells at small scale: numerical and experimental investigations,” Bioengineering, vol. 5, pp. 106, 2018. https://doi.org/10.3390/bioengineering5040106.Search in Google Scholar PubMed PubMed Central
© 2024 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Frontmatter
- Articles
- Study on mixing characteristics of viscoplastic fluid in a rigid-flexible impeller stirred tank
- Emission and performance investigation of mango seed oil biodiesel supplied with n-pentanol and n-hexanol additives and optimization of fuel blends using modified deep neural network
- Study of chlorophyll dye from peppermint (mentha spicata) used as a sensitizer in TiO2 solar cells
- Dry reforming of methane over Ni–Mg–Al and Ni–Ca–Al type hydrotalcite-like catalysts: effects of synthesis route and Ru incorporation
- CFD-DEM simulation of chemical looping hydrogen generation in a moving bed reactor
- Conceptual design of a fixed bed N2O decomposition reactor with a heat pipe heat exchanger
- Investigation of polymers pyrolysis in a solid-gas conical spouted bed: CFD simulation
- CFD simulation study of internal mixing and flow of a modified airlift bioreactor
- Mechanism analysis and mixing characterization of variable-speed mechanical mixing enhancement
- Enhanced sonocatalytic degradation of Acid Red 27 with Fe2O3 catalyst: a kinetic study
Articles in the same Issue
- Frontmatter
- Articles
- Study on mixing characteristics of viscoplastic fluid in a rigid-flexible impeller stirred tank
- Emission and performance investigation of mango seed oil biodiesel supplied with n-pentanol and n-hexanol additives and optimization of fuel blends using modified deep neural network
- Study of chlorophyll dye from peppermint (mentha spicata) used as a sensitizer in TiO2 solar cells
- Dry reforming of methane over Ni–Mg–Al and Ni–Ca–Al type hydrotalcite-like catalysts: effects of synthesis route and Ru incorporation
- CFD-DEM simulation of chemical looping hydrogen generation in a moving bed reactor
- Conceptual design of a fixed bed N2O decomposition reactor with a heat pipe heat exchanger
- Investigation of polymers pyrolysis in a solid-gas conical spouted bed: CFD simulation
- CFD simulation study of internal mixing and flow of a modified airlift bioreactor
- Mechanism analysis and mixing characterization of variable-speed mechanical mixing enhancement
- Enhanced sonocatalytic degradation of Acid Red 27 with Fe2O3 catalyst: a kinetic study
