Human adenovirus-36 seropositivity and obesity among Midwestern US adolescents
-
Aneesh K. Tosh
,
Mollie G. Wasserman
Abstract
Objective
Human adenovirus-36 (Ad-36) infection has been implicated as a risk factor for obesity. This study aims to measure Ad-36 antibody prevalence among obese and healthy-weight Midwestern US adolescents.
Methods
Obese and healthy-weight subjects 10–18 years of age attending an adolescent clinic in Missouri, USA, were tested for Ad-36 antibodies via ELISA assay. All subjects were measured for height and weight to determine body mass index (BMI). χ2 analysis was used to compare Ad-36 antibody prevalence between the two groups.
Results
Ad-36 antibodies were tested on 41 obese and 37 control subjects. The subjects’ mean age at the time of sample collection was 15.6 years (SD 2.0). Ad-36 antibody prevalence was 43.9% among the obese group and 21.6% among the control group (p = 0.038).
Discussion
The findings show that statistically more obese Missouri adolescents test positive for Ad-36 antibodies than their healthy-weight peers, consistent with previous findings suggesting a correlation between Ad-36 infection and obesity.
Acknowledgments
Dr. Richard Atkinson, Obetech Laboratory, Virginia, USA. Drs. Richard Madsen and Bin Ge, University of Missouri Department of Biostatistics, Columbia, MO, USA.
Funding source: This research was supported by the Forrest O. Sears and Leda J. Sears Trust awarded to A.K.T.
Conflict of interest: The authors have no conflicts, real or perceived.
[1] Atkinson RL, Lee I, Shin HJ, He J. Human adenovirus-36 antibody status is associated with obesity in children. Int J Pediatr Obes. 2010;5(2):157–60.10.3109/17477160903111789Suche in Google Scholar PubMed
[2] Gabbert C, Donohue M, Arnold J, Schwimmer JB. Adenovirus 36 and obesity in children and adolescents. Pediatrics. 2010;126(4):721–6.10.1542/peds.2009-3362Suche in Google Scholar PubMed
[3] Almgren M, Atkinson R, He J, Hilding A, Hagman E, Wolk A, et al. Adenovirus-36 is associated with obesity in children and adults in Sweden as determined by rapid ELISA. PLoS One. 2012;7(7):e41652.10.1371/journal.pone.0041652Suche in Google Scholar PubMed PubMed Central
[4] Na HN, Hong YM, Kim J, Kim HK, Jo I, Nam JH. Association between human adenovirus-36 and lipid disorders in Korean schoolchildren. Int J Obes. 2010;34(1):89–93.10.1038/ijo.2009.207Suche in Google Scholar PubMed
[5] Atkinson RL, Dhurandhar NV, Allison DB, Bowen RL, Israel BA, Albu JB, et al. Human adenovirus-36 is associated with increased body weight and paradoxical reduction of serum lipids. Int J Obes. 2005;29(3):281–6.10.1038/sj.ijo.0802830Suche in Google Scholar PubMed
[6] Tosh AK, Bray-Aschenbrenner A, El Khatib J, Ge B. Adenovirus-36 antibody status & BMI comparison among obese Missouri adolescents. Mo Med. 2011;109(5):402–3.Suche in Google Scholar
©2017 Walter de Gruyter GmbH, Berlin/Boston
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