Protein engineering comes of age

Articles in the same Issue

1. Frontmatter
2. Protein engineering comes of age
3. Microbial transglutaminase for biotechnological and biomedical engineering
4. Computational design of structured loops for new protein functions
5. Formylglycine-generating enzymes for site-specific bioconjugation
6. Chemical modification of neuropeptide Y for human Y₁ receptor targeting in health and disease
7. Manipulating the stereoselectivity of a thermostable alcohol dehydrogenase by directed evolution for efficient asymmetric synthesis of arylpropanols
8. Radiometal-labeled anti-VCAM-1 nanobodies as molecular tracers for atherosclerosis – impact of radiochemistry on pharmacokinetics
9. Hit evaluation of an α-helical peptide: Ala-scan, truncation and sidechain-to-sidechain macrocyclization of an RNA polymerase Inhibitor
10. Highly flexible, IgG-shaped, trivalent antibodies effectively target tumor cells and induce T cell-mediated killing
11. An engineered lipocalin that tightly complexes the plant poison colchicine for use as antidote and in bioanalytical applications
12. Sequence selection by FitSS4ASR alleviates ancestral sequence reconstruction as exemplified for geranylgeranylglyceryl phosphate synthase
13. Facile generation of antibody heavy and light chain diversities for yeast surface display by Golden Gate Cloning
14. Peptide binding affinity redistributes preassembled repeat protein fragments
15. Directed evolution of the 3C protease from coxsackievirus using a novel fluorescence-assisted intracellular method
16. Rational design of an improved photo-activatable intein for the production of head-to-tail cyclized peptides
17. Characterization and engineering of photoactivated adenylyl cyclases