A position paper of the EFLM Committee on Education and Training and Working Group on Distance Education Programmes/E-Learning: developing an e-learning platform for the education of stakeholders in laboratory medicine
-
Damien Gruson
, Gilbert Faure
, Bernard Gouget , Alexandre Haliassos , Darya Kisikuchin , Henrique Reguengo , Elizabeta Topic and Victor Blaton
Abstract
The progress of information and communication technologies has strongly influenced changes in healthcare and laboratory medicine. E-learning, the learning or teaching through electronic means, contributes to the effective knowledge translation in medicine and healthcare, which is an essential element of a modern healthcare system and for the improvement of patient care. E-learning also represents a great vector for the transfer knowledge into laboratory practice, stimulate multidisciplinary interactions, enhance continuing professional development and promote laboratory medicine. The European Federation of Laboratory Medicine (EFLM) has initiated a distance learning program and the development of a collaborative network for e-learning. The EFLM dedicated working group encourages the organization of distance education programs and e-learning courses as well as critically evaluate information from courses, lectures and documents including electronic learning tools. The objectives of the present paper are to provide some specifications for distance learning and be compatible with laboratory medicine practices.
Table of contents
Overview of e-learning
The rational for e-learning
Developing an effective e-learning platform for stakeholders in laboratory medicine
Determine the needs and educational objectives
Prepare the content according to the needs and educational objectives
Specify the expected outcomes
Determine the technical needs and resources
Encourage active learning
Stimulate the use of credits for continuing professional development
Identify the challenges prior to implementation
Conclusions
References
I. Overview of e-learning
The progress of information and communication technologies (ICT) has strongly influenced changes in healthcare and laboratory medicine. The rise of ICT in science, healthcare and laboratory medicine is also stimulating a change in education with the incorporation of more e-learning in education, training and knowledge transfer. E-learning is related to learning or teaching through electronic means, such as internet, intranet, or other multimedia materials like audio or video tape, satellite television and CD-ROMs [1–3]. E-learning enables the transfer of knowledge and skills through web-based learning, computer-based learning, virtual education opportunities and digital collaborations [1–3]. E-learning is now frequently incorporated into conventional programs and several approaches have been associated with this new way of learning such as problem-based learning, self-directed learning, case-based learning, just-in-time learning, e-journal club, e-courses and virtual patients [2–5]. The current emergence of e-learning is due to the progress of technologies with more capabilities, connectivity, learning tools and user friendly interfaces [2–5]. E-learning is a revolution in education but as our lives and professional environments rely more and more on ICT, e-learning is also able to respond to the requests of ICT consumers. E-learning is also able to support the effective knowledge translation in medicine and healthcare, which is an essential element of a modern healthcare system and can contribute to the improvement of patient care [4–7].
II. The rational for e-learning
The positive potential of e-learning is undeniable. E-learning is particularly effective at engaging young people and might enable the improvement of inter-professional team interactions, life-long learning, practice performance, certificate programs and curriculum standardization [1–4]. E-learning presents several other advantages and might help to break barriers with more flexible learning opportunities. Indeed, e-learning enables learners’ travel costs and times to be reduced, the selection of learning materials to meet a specific level of knowledge, an appropriate learning style to be chosen, the development of computer and internet skills, the stimulation of self-knowledge and self-confidence, the generation of useful supplementary materials to conventional programs and peer-reviewed electronic resources to be provided [1–4].
The efficiency and cost effectiveness of e-learning for education and teaching in the medical era have been documented by several reports (Table 1). In laboratory medicine, e-learning is offering several opportunities for the education and professional improvement of stakeholders, for the appropriate use of laboratory tests and for the improvement of patient care. More precisely, e-learning in laboratory medicine could help to reach several educational goals and curriculum needs in multiple fields (hematology, chemistry, forensic toxicology, clinical immunology, microbiology, blood gas laboratory, specialized care center laboratory…), fulfill some of the accreditation requirements for the management of competences and skills, disseminate evidence-based clinical practice guidelines, promote innovation, provide several learning resources, improve working conditions and efficiency and target outcomes oriented on patients [6, 7, 15, 16]. E-learning is also representing a great vector for the transfer of knowledge into laboratory practice, to stimulate multidisciplinary interactions, to enhance continuing professional development and to promote laboratory medicine.
Efficiency of e-learning in healthcare.

Several challenges are, however, paving the way of e-learning such as access to the appropriate computer and technology, the need of efficient virtual teaching supports, and standardization of contents and guidance for both learners and teachers [1–4]. Some important issues are also related to the ability to develop multidisciplinary peer-review processes of e-learning materials and the building of efficient e-learning programs able to support the credited continuing professional development of stakeholders in laboratory medicine [4, 16].
III. Developing an effective e-learning platform for stakeholders in laboratory medicine
In 2010, EFLM initiated a distance learning program and began the development of a collaborative network for e-learning. The EFLM dedicated working group encourages the organization of distance education programs and e-learning courses as well as critically evaluate information from courses, lectures and documents including electronic learning tools.
Therefore, the objectives of the present paper are to provide some specifications for distance learning, compatible with laboratory medicine and inspired by the Kirkpatrick model based on learner satisfaction, learning outcome, performance improvement and patient and health outcomes [17–24].
1. Determine the needs and educational objectives
Establish the best way to catch the needs and educational preferences of the learners
Collect the needs and potential pre-determined desired themes
Identify and analyze the educational needs and preferences of the learners
State the aim(s) and educational objectives of the course/training
Identify the best way to reach the audience
Define the format use for the content and a protocol able to face the needs and educational objectives
Define the target audience
Consider the potential barriers for the release of the course
2. Prepare the content according to the needs and educational objectives
Define the educational objectives and expected outcomes
The content should be defined and prepared according to the educational objectives and expected outcomes
The content should be adequate, relevant, realistic and well organized
The content should be evidence-based and pedagogical
The content should be prepared according to relevant ethical, medico-legal and legal requirements
The content should be interactive and provide links to further relevant information
The likely duration of the course should be stated
The content/course should be available as needed and when needed
The content should be flexible and responsive to learners
The date of preparation of the content and related materials should be mentioned
The content should meet national and international standards
The content should be balanced, free of bias and potential conflicts of interest should be stated
The content and related materials should be copyright authorized
The content should be peer-reviewed and ideally include multidisciplinary peer reviewing process
A description and qualification of the teachers, speakers and producers should be provided
3 Specify the expected outcomes
Describe the potential gain of knowledge
Describe the potential acquired skills
Describe the potential acquired competences
Specify the potential transfer to work situations
Define the potential improvement of curriculum content
State the certificate that can be reached after the course through quizzes and examination
4. Determine the technical needs and resources
Identify and evaluate the available relevant software(s) and equipment
The selected technical solution should be usable according to the criteria for web-based materials
The teachers, speakers and producers should be trained to the selected solution
The selected technical solution should fit the expected number of participants
The technical solution should allow effective means for the learner to provide feedback on the materials
The selected technical solution should allow the creation of a portfolio of acquired skills and knowledge
The selected technical solution should facilitate an intuitive management of records
The selected technical solution should provide a confidential treatment of records and learner profiles
The selected technical solution should facilitate the registration procedures
The selected technical solution should engage and support learners
The selected technical solution should meet national and international standards
5. Encourage active learning
Stimulate learner assessment through quizzes and examination
Evaluate the learner with objectives questions related to the content and educational objectives
Catch the learner feedback with online evaluation form
Ensure a secured and confidential learner assessment and evaluation
Ensure the appropriate authentication of the learner
6. Stimulate the use of credits for continuing professional development (CPD)
Stimulate the building of an interactive online CPD platform that can support active learning and establish an additional stimulus for knowledge translation into daily medical practice
Request CPD credits recognized by a relevant professional accreditation and by employers
Respect the guidelines to obtain CPD credits
7. Identify the challenges prior to implementation
Define the project management and its time line
Learn about internet and computer skills
Structure a business plan and a budget
Work on an evolutive and interactive content
Structure the peer-reviewing process of the content
Schedule the maintenance of the software and equipment
Request for continuing professional development credits
Identify the online support group
IV. Conclusions
E-learning is a revolution for the education of healthcare professionals and stakeholders in laboratory medicine. E-learning offers huge opportunities for learning and access to a vast amount of knowledge as well as providing an additional stimulus for knowledge translation into daily medical practice. E-learning programs might also enhance the performance of the stakeholders in laboratory medicine, support the need of more managed competences and improve patient care and safety.
The role of EFLM and international societies of laboratory medicine is to develop e-learning programs for stakeholders in laboratory medicine, ensure the value of e-learning solutions and programs developed for stakeholders in laboratory medicine and establish core standards for e-learning in laboratory medicine.
Conflict of interest statement
Authors’ conflict of interest disclosure: The authors stated that there are no conflicts of interest regarding the publication of this article.
Research funding: None declared.
Employment or leadership: None declared.
References
1. Sajeva M. E-learning: web-based education. Curr Opin Anaesthesiol 2006;19:645–9.10.1097/ACO.0b013e328010bec8Search in Google Scholar PubMed
2. Masic I, Pandza H, Kulasin I, Masic Z, Valjevac S. Tele-education as method of medical education. Med Arh 2009;63:350–3.10.5455/medarh.2009.63.350-353Search in Google Scholar PubMed
3. McKimm J, Jollie C, Cantillon P. ABC of learning and teaching: web based learning. Br Med J 2003;19:870–3.10.1136/bmj.326.7394.870Search in Google Scholar PubMed PubMed Central
4. Ruiz JG, Mintzer MJ, Leipzig RM. The impact of E-learning in medical education. Acad Med 2006;81:207–12.10.1097/00001888-200603000-00002Search in Google Scholar PubMed
5. Triola MM, Huwendiek S, Levinson AJ, Cook DA. New directions in e-learning research in health professions education: report of two symposia. Med Teach 2012;34:e15–20.10.3109/0142159X.2012.638010Search in Google Scholar PubMed
6. Wilkinson A, While AE, Roberts J. Measurement of information and communication technology experience and attitudes to e-learning of students in the healthcare professions: integrative review. J Adv Nurs 2009;65:755–72.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000263757700005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=b7bc2757938ac7a7a821505f8243d9f310.1111/j.1365-2648.2008.04924.xSearch in Google Scholar PubMed
7. Kulier R, Hadley J, Weinbrenner S, Meyerrose B, Decsi T, Horvath AR, et al. Harmonising evidence-based medicine teaching: a study of the outcomes of e-learning in five European countries. BMC Med Educ 2008;8:1–.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000207735100027&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=b7bc2757938ac7a7a821505f8243d9f3Search in Google Scholar
8. Bandla H, Franco RA, Simpson D, Brennan K, McKanry J, Bragg D. Assessing learning outcomes and cost effectiveness of an online sleep curriculum for medical students. J Clin Sleep Med 2012;8:439–43.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000310059400014&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=b7bc2757938ac7a7a821505f8243d9f3Search in Google Scholar PubMed
9. Gordon M, Chandratilake M, Baker P. Improved junior paediatric prescribing skills after a short e-learning intervention: a randomised controlled trial. Arch Dis Child 2011;96:1191–4.10.1136/archdischild-2011-300577http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000296923000022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=b7bc2757938ac7a7a821505f8243d9f3Search in Google Scholar PubMed
10. Hadley J, Kulier R, Zamora J, Coppus SF, Weinbrenner S, Meyerrose B, et al. Effectiveness of an e-learning course in evidence-based medicine for foundation (internship) training. J R Soc Med 2010;103:288–94.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000279889200011&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=b7bc2757938ac7a7a821505f8243d9f310.1258/jrsm.2010.100036Search in Google Scholar PubMed PubMed Central
11. Abdelhai R, Yassin S, Ahmad MF, Fors UG. An e-learning reproductive health module to support improved student learning and interaction: a prospective interventional study at a medical school in Egypt. BMC Med Educ 2012;12:1–9.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000305183500001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=b7bc2757938ac7a7a821505f8243d9f3Search in Google Scholar
12. Mehrdad N, Zolfaghari M, Bahrani N, Eybpoosh S. Learning outcomes in two different teaching approach in nursing education in Iran: e-learning versus lecture. Acta Med Iran 2011;49:296–301.Search in Google Scholar
13. Schroter S, Jenkins RD, Playle RA, Walsh KM, Probert C, Kellner T, et al. Evaluation of an online interactive Diabetes Needs Assessment Tool (DNAT) versus online self-directed learning: a randomised controlled trial. BMC Med Educ 2011;11:1–9.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000292495900001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=b7bc2757938ac7a7a821505f8243d9f3Search in Google Scholar
14. Woelber JP, Hilbert TS, Ratka-Krüger P. Can easy-to-use software deliver effective e-learning in dental education? A randomised controlled study. Eur J Dent Educ 2012;16:187–92.10.1111/j.1600-0579.2012.00741.xSearch in Google Scholar PubMed
15. Pazzagli M, McMurray J, Zerah S. The EC4 European Register of Specialists in Clinical Chemistry and Laboratory Medicine. Clin Chim Acta 2008;393:27–30.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000257943300008&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=b7bc2757938ac7a7a821505f8243d9f310.1016/j.cca.2008.03.027Search in Google Scholar PubMed
16. Maillet B, Maisonneuve H. Long-life learning for medical specialists doctors in Europe: CPD, DPC and qualification. Presse Med 2011;40:357–65.10.1016/j.lpm.2011.01.014http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000290647400005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=b7bc2757938ac7a7a821505f8243d9f3Search in Google Scholar PubMed
17. Lau F, Bates J. A review of e-learning practices for undergraduate medical education. J Med Syst 2004;28:71–87.10.1023/B:JOMS.0000021522.30587.ffSearch in Google Scholar
18. Grijpink-van den Biggelaar K, Drop SL, Schuwirth L. Development of an e-learning portal for pediatric endocrinology: educational considerations. Horm Res Paediatr 2010;73:223–30.10.1159/000284366Search in Google Scholar PubMed
19. Brouwers MC, Makarski J, Durocher LD, Levinson AJ. E-learning interventions are comparable to user’s manual in a randomized trial of training strategies for the AGREE II. Implement Sci 2011;6:1–10.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000294332100001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=b7bc2757938ac7a7a821505f8243d9f3Search in Google Scholar
20. Vollmar HC, Schürer-Maly CC, Frahne J, Lelgemann M, Butzlaff M. An e-learning platform for guideline implementation – evidence- and case-based knowledge translation via the Internet. Methods Inf Med 2006;45:389–96.10.1055/s-0038-1634093Search in Google Scholar
21. Keyte D, Richardson C. Re-thinking pain educational strategies: pain a new model using e-learning and PBL. Nurse Educ Today 2011;31:117–21.10.1016/j.nedt.2010.05.001http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000287684900003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=b7bc2757938ac7a7a821505f8243d9f3Search in Google Scholar PubMed
22. Mazzoleni MC, Rognoni C, Finozzi E, Landro M, Capodaglio E, Imbriani M, et al. Earnings in e-learning: knowledge, CPD credits or both? Hints from analysis of attendance dynamics and users’ behaviour. Stud Health Technol Inform 2010;160:576–80.Search in Google Scholar
23. Knight CL, Sakowski HA, Houghton BL, Laya MB, DeWitt DE. Developing a peer review process for web-based curricula: minting a new coin of the realm. J Gen Intern Med 2004;19: 594–8.10.1111/j.1525-1497.2004.30218.xSearch in Google Scholar PubMed PubMed Central
24. The Accreditation of e-Learning Materials by the EACCME. Available at: http://www.uems.net.Search in Google Scholar
©2013 by Walter de Gruyter Berlin Boston
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- Evaluation of [−2] proPSA and Prostate Health Index (phi) for the detection of prostate cancer: a systematic review and meta-analysis
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