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Two site evaluation of the performance of a new generation point-of-care glucose meter for use in a neonatal intensive care unit

  • Kristina A. Tendl EMAIL logo , Jürgen Christoph , Adele Bohn , Kurt R. Herkner , Arnold Pollak and Andrea-Romana Prusa
Published/Copyright: April 6, 2013
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Clinical Chemistry and Laboratory Medicine
From the journal Clinical Chemistry and Laboratory Medicine Volume 51 Issue 9

Abstract

Background: Monitoring of blood glucose in neonatal intensive care unit (NICU) patients is important in maintaining normoglycaemia and reducing the risk of hypoglycaemia. Point-of-care testing (POCT) glucose meters provide short turnaround times but some have been reported to be affected by haematocrit interference and other biochemical or biological substances in their accuracy and performance. The aim of this study was to assess the performance of a new POCT glucose meter in a challenging preterm neonatal population.

Methods: The new Nova Biomedical StatStrip™ (Nova Biomedical) was tested on 159 heparinised whole blood samples from NICU patients obtained for blood gas analysis. Accuracy (bias) of the meter and analytical interferences were evaluated by comparing the results of the meter with the results of the blood gas analyser routinely used for glucose measurements in this NICU setting.

Results: The results of the StatStrip glucose meter correlated very well with the reference routine method across a wide glucose concentration range (13–389 mg/dL) and were not affected by the level of haematocrit, by sample pH or by medication.

Conclusions: The StatStrip meter showed good clinical accuracy and performance for measuring and monitoring glucose levels in NICU patients, with special respect to preterm infants, and therefore can act as a perfect alternative to a blood gas analyser for measuring blood glucose in NICU patients.

Keywords: glucometer; glucose measurement; neonatology; Nova StatStrip; point-of-care testing (POCT)
Corresponding author: Kristina A. Tendl, MD, Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, 1090 Vienna, Austria, Phone: +43 1 404002148, Fax: +43 1 404003200

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Received: 2012-12-10
Accepted: 2013-3-8
Published Online: 2013-04-06
Published in Print: 2013-09-01

©2013 by Walter de Gruyter Berlin Boston

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https://doi.org/10.1515/cclm-2012-0864
Keywords for this article
glucometer; glucose measurement; neonatology; Nova StatStrip; point-of-care testing (POCT)

Articles in the same Issue

  1. Masthead
  2. Masthead
  3. Editorials
  4. What is a biomarker? It’s time for a renewed definition
  5. Biomarker research and leading causes of death worldwide: a rather feeble relationship
  6. Thiosulfate in urine: new hope or new failure of a biomarker for prostate cancer?
  7. Review
  8. Acute coronary syndrome – the present and future role of biomarkers1)
  9. Mini Review
  10. Advance in molecular diagnostic tools for hepatitis B virus detection
  11. Opinion Paper
  12. Standardization and analytical goals for glycated hemoglobin measurement
  13. Guidelines and Recommendations
  14. Proposal for the use in emergency departments of cardiac troponins measured with the latest generation methods in patients with suspected acute coronary syndrome without persistent ST-segment elevation
  15. General Clinical Chemistry and Laboratory Medicine
  16. Current status of verification practices in clinical biochemistry in Spain
  17. Two site evaluation of the performance of a new generation point-of-care glucose meter for use in a neonatal intensive care unit
  18. Trp64Arg (rs4994) polymorphism of β3-adrenergic receptor gene is associated with hyperuricemia in a Chinese male population
  19. Quantification of vancomycin in human serum by LC-MS/MS
  20. Automated indirect immunofluorescence antinuclear antibody analysis is a standardized alternative for visual microscope interpretation
  21. Autocorrelation and cross-correlation between hCGβ and PAPP-A in repeated sampling during first trimester of pregnancy
  22. Platelet oxidative stress and systemic inflammation in chronic spontaneous urticaria
  23. Reference Values
  24. Establishment of reference values for novel urinary biomarkers for renal damage in the healthy population: are age and gender an issue?
  25. Risks of mortality associated with common laboratory tests: a novel, simple and meaningful way to set decision limits from data available in the Electronic Medical Record
  26. Cancer Diagnostics
  27. Cancer antigen 125, human epididymis 4, kallikrein 6, osteopontin and soluble mesothelin-related peptide immunocomplexed with immunoglobulin M in epithelial ovarian cancer diagnosis
  28. Thiosulfate in urine as a facilitator in the diagnosis of prostate cancer for patients with prostate-specific antigen less or equal 10 ng/mL
  29. Anemia and iron biomarkers in patients with early breast cancer. Diagnostic value of hepcidin and soluble transferrin receptor quantification1)
  30. Sensitive detection of EML4-ALK fusion oncoprotein of lung cancer by in situ proximity ligation assay
  31. Re-evaluation of laboratory predictors of response to current anemia treatment regimens of erythropoiesis stimulating agents in cancer patients
  32. Cardiovascular Diseases
  33. Evaluation of four sensitive troponin assays for risk assessment in acute coronary syndromes using a new clinically oriented approach for comparison of assays
  34. A combined index of cardiac biomarkers as a risk factor for early cardiovascular mortality in hemodialysis patients
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