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Towards new diagnostic criteria for diagnosing GDM – the HAPO study
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Eran Hadar
Veröffentlicht/Copyright:
1. September 2009
Abstract
Gestational diabetes mellitus (GDM) is defined as a carbohydrate intolerance, with onset or first recognition during pregnancy. The prevalence of GDM, and the occurrence of related complications, depends upon the definition of normal glucose values during gestation. The diagnostic criteria for GDM are controversial mainly because they lack correlation to outcome, be it maternal or perinatal. To date, there are no risk based guidelines to make the diagnosis of GDM and determine practice guidelines that are extrapolated from perinatal and maternal outcome and endpoints. To answer some of the above-mentioned controversies, the hyperglycemia and adverse pregnancy outcome study (HAPO) was planned and executed. This review outlines the results of the HAPO study, which demonstrates that fasting glucose levels and post 75 g OGTT are correlated to maternal, perinatal and neonatal outcomes. It is anticipated that the international recommendation for GDM diagnosis, will be shortly published.
Received: 2009-5-6
Revised: 2009-7-21
Accepted: 2009-7-23
Published Online: 2009-09-01
Published in Print: 2009-09-01
©2009 by Walter de Gruyter Berlin New York
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Schlagwörter für diesen Artikel
Gestational diabetes mellitus;
hyperglycemia and adverse pregnancy outcome (HAPO) study
Artikel in diesem Heft
- Recommendations and guidelines for perinatal practice
- Guidelines on CMV congenital infection
- Minireviews
- Towards new diagnostic criteria for diagnosing GDM – the HAPO study
- Surveillance during labour
- Limit of viability in Japan: ethical consideration
- Review article
- Outpatient induction – how safe
- Original articles – Obstetrics
- Increased inositol phosphoglycan P-type in the second trimester in pregnant women with type 2 and gestational diabetes mellitus
- A randomized trial of cerclage vs. 17 α-hydroxyprogesterone caproate for treatment of short cervix
- Umbilical cord insertion site in early gestation and development of placenta
- Inappropriate use of vancomycin for preventing perinatal group B streptococcal (GBS) disease in laboring patients
- Vitamin D receptor genotype BB is associated with higher serum osteocalcin in first pregnancy
- Arylsulphatase A activity and sulphatide concentration in placenta, membranes and cord after delivery
- Amniotic fluid angiopoietin-2 in term and preterm parturition, and intra-amniotic infection/inflammation
- Long chain polyunsaturated fatty acids in mothers and term babies
- Body mass index, Bishop score, and sonographic measurement of the cervical length as predictors of successful labor induction in twin gestations
- Original articles – Fetus
- Coiling characteristics of umbilical cords in breech vs. vertex presentation
- Fetal short time variation during labor: a non-invasive alternative to fetal scalp pH measurements?
- Prenatal diagnosis and postnatal management of meconium peritonitis
- When uncertainty generates more anxiety than severity: the prenatal experience with cystic adenomatoid malformation of the lung
- Evidence of changes in the immunophenotype and metabolic characteristics (intracellular reactive oxygen radicals) of fetal, but not maternal, monocytes and granulocytes in the fetal inflammatory response syndrome
- Original articles – Newborn
- Nicotine affects the expression of brain-derived neurotrophic factor mRNA and protein in the hippocampus of hypoxic newborn piglets
- Effect of exogenous surfactant therapy on levels of pulmonary surfactant proteins A and D in preterm infants with respiratory distress syndrome
- Letters to the Editor
- Use and abuse of cesarean section – a transatlantic evaluation
- Elective cesarean delivery at 38 weeks' gestation: Is the timing too early?
- Grasping activity in utero: a significant indicator of fetal behavior (The role of the grasping reflex in fetal ethology)
- Reply
- Prevention of intrauterine growth restriction: are there no effective methods available?
- Obituary
- The death of Prof. Albert Huch
- Congress calendar
- Congress Calendar
- Erratum
- Hematological profile of Korean very low birth weight infants
