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Reference range of fetal lung volume by 3D-ultrasonography using the rotational method (VOCAL)

  • Ingrid Schwach Werneck Britto , Luiz Cláudio de Silva Bussamra , Edward Araujo Júnior , Giselle Daharem Tedesco , Luciano Marcondes Machado Nardozza , Antonio Fernandes Moron and Tsutomu Aoki
Published/Copyright: November 10, 2008
Journal of Perinatal Medicine
From the journal Volume 37 Issue 2

Abstract

Aim: To determine reference ranges for fetal lung volume by 3-dimensional ultrasonography using the VOCAL (Virtual Organ Computed-aided Analysis) method.

Methods: A longitudinal prospective study was conducted with 61 uncomplicated pregnancies between 24 and 32 weeks of gestation. A separate measurement of both lungs volume was conducted by VOCAL with 30° rotation angle. For each gestational age, an average, standard deviation and maximal and minimal values were established in addition to the percentiles 5, 10, 25, 50, 75 and 90 for right and left lung volume. To evaluate the correlation between lung volume and gestational age, and estimated fetal weight, a polynomial regression with determination coefficient adjustment (R2) was used. The intra-observer reproducibility was evaluated by the intraclass correlation coefficient (ICC), whereas the inter-observer reproducibility was evaluated by Cronbach alpha statistic test.

Results: The average right lung volume varied from 12.5±0.7 cm3 at the 24th week to 31.8 cm3±1.8 cm3 at the 32nd week. The average left lung volume varied from 9.2±0.9 cm3 at the 24th week to 22.0 cm3±1.6 cm3 at the 32nd week. We observed a strong correlation between right lung volume and gestational age (R2=0.975) and estimated fetal weight (R2=0.905), as well as between the left lung volume with gestational age (R2=0.970) and estimated fetal weight (R2=0.908). We observed a good intra-observer reproducibility for the right lung volume (ICC=0.990) and for the left lung volume (ICC=0.986). Similarly, we observed good inter-observer reproducibility for right lung volume (0.975) and left lung volume (0.962).

Conclusion: Reference range of fetal lung volume by 3D-ultrasonography using the VOCAL method was determined.

Keywords: Fetal lung volume; nomogram; three-dimensional ultrasonography; VOCAL
Corresponding author: Edward Araujo Júnior Rua Carlos Weber 950 apto. 113 Visage Alto da Lapa São Paulo – SP CEP 05303-000 Brazil Tel./fax: +55-11-3294-3220
Received: 2008-5-27
Revised: 2008-8-1
Accepted: 2008-8-15
Published Online: 2008-11-10
Published Online: 2008-11-10
Published in Print: 2009-03-01

©2009 by Walter de Gruyter Berlin New York

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https://doi.org/10.1515/JPM.2009.023
Keywords for this article
Fetal lung volume; nomogram; three-dimensional ultrasonography; VOCAL

Articles in the same Issue

  1. Selected articles from the 31st scientific meeting of the New York Perinatal Society on May 19, 2008
  2. Advanced maternal age as a sole indication for genetic amniocentesis; risk-benefit analysis based on a large database reflecting the current common practice
  3. Risks for common medical conditions experienced by former preterm infants during toddler years
  4. Predictors of severe perineal lacerations in Chinese women
  5. Maternal and neonatal outcomes in early glucose tolerance testing in an obstetric population in New York city
  6. Original articles – Obstetrics
  7. Prelabor rupture of membranes at term requiring labor induction – a feature of occult fetal cephalopelvic disproportion?
  8. Group B Streptococcus colonization in pregnancy: prevalence and prevention strategies of neonatal sepsis
  9. Preterm labor and bacterial vaginosis-associated bacteria among urban women
  10. Lipopolysaccharide binding protein in the early diagnosis of intraamniotic infection of pregnant women with premature rupture of the membranes
  11. Perinatal outcomes after second trimester detection of amniotic fluid viral genome in asymptomatic patients
  12. Is induced abortion a risk factor in subsequent pregnancy?
  13. An approach to the prediction of neonatal Erb palsy
  14. External cephalic version among women with a previous cesarean delivery: report on 36 cases and review of the literature
  15. Original articles – Fetus
  16. Reference range of fetal lung volume by 3D-ultrasonography using the rotational method (VOCAL)
  17. Sex differences in linear and complex fetal heart rate dynamics of normal and acidemic fetuses in the minutes preceding delivery
  18. Misidentification of maternal for fetal heart rate patterns after delivery of the first twin
  19. Original articles – Newborn
  20. Prevalence and risk factors for hypothermia on admission in Nigerian babies <72 h of age
  21. Influence of sociodemographic and psychosocial characteristics on breastfeeding duration of mothers attending breastfeeding support groups
  22. Congress Calender
  23. Congress Calendar
  24. WAPM-Newsletter 1/2009: Istanbul Declaration on following Ethics in Perinatal Medicine
  25. WAPM-Newsletter No 1/2009
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