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Below median birth weight in appropriate-for-gestational-age preterm infants as a risk factor for bronchopulmonary dysplasia
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Gabriele Kewitz
Published/Copyright:
July 3, 2008
Abstract
Aims: To assess the presence of chorioamnionitis and intrauterine growth as prenatal risk factors for broncho pulmonary dysplasia (BPD) in appropriate-for-gestational-age (AGA) infants of <28 weeks' gestation.
Methods: Gender, race, birth weight, gestational age, histology of the placenta, diagnosis of BPD at 36 weeks' gestation, postnatal dexamethasone treatment, and death were recorded in 150 preterm infants born at <28 weeks' gestation, and admitted between 1996 and 2001.
Results: In 122 AGA infants (mean gestational age: 26.18 weeks, mean birth weight: 837 g), BPD was associated with gestational age-related birth weights below the 50th centile. Intrauterine growth deceleration started between 25 and 26 weeks' gestation. Chorioamnionitis was not related to BPD.
Conclusions: AGA infants of 26–28 weeks' gestation with birth weights below the median showed an increased risk of developing BPD.
Keywords: Appropriate-for-gestational-age; broncho-pulmonary dysplasia; chorioamnionitis; dexamethasone; extremly-low-birth-weight infants; intrauterine growth; intrauterine infection; placenta histology; preterm infants
Received: 2007-10-23
Revised: 2008-3-5
Accepted: 2008-3-19
Published Online: 2008-07-03
Published in Print: 2008-07-01
©2008 by Walter de Gruyter Berlin New York
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- Does globalization and change demand a different kind of perinatal research?
- Recommendations and guidelines for perinatal practice
- Intrauterine restriction (IUGR)
- Review article
- The role of antioxidant vitamins in hypertensive disorders of pregnancy
- Original articles – Obstetrics
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