Obstetric antecedents for preterm delivery
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Michael M. Slattery
Abstract
Objectives: To investigate the obstetric antecedents for preterm delivery (PTD) in an Irish urban obstetric population, and to evaluate the incidence and outcome of such deliveries.
Study design: A retrospective observational study of all preterm deliveries at the Rotunda Hospital, Dublin during the six-year period 1997–2002. The findings for early preterm deliveries (EPTD) (24+0–31+6 weeks' gestation), and late preterm deliveries (LPTD) (32+0–36+6 weeks' gestation) were analyzed separately.
Results: There were 38,795 deliveries after 24 weeks' gestation or >500 g birth weight, of which 2839 (7.3%) were preterm. Of all preterm deliveries, 626 (22.1%) were EPTD and 2213 (77.9%) were LPTD, resulting in an EPTD rate of 1.6% and an LPTD rate of 5.7%. Spontaneous unexplained preterm delivery accounted for 1221 (43.0%) of preterm deliveries (PTD), and of these 213 (34%) cases were EPTD and 1008 (45.5%) LPTD. The other most frequently observed obstetric causative factors, in order of importance, were multiple gestation (676; 23.8% of PTD), hypertensive disorders of pregnancy (243; 8.6%), antepartum hemorrhage (194; 6.8%), stillbirth (105; 3.7%), intrauterine growth restriction (53; 1.9%) and preterm prelabor rupture of membranes±chorioamnionitis (32; 1.1%). There were 75 early neonatal deaths among infants born prematurely, plus 105 stillbirths, resulting in a perinatal mortality rate of 63 per 1000 for PTD (n=180), which on subsequent analysis was 158 per 1000 for EPTD (n=99) and 37 per 1000 for LPTD (n=81).
Conclusions: These data outline the obstetric factors linked to preterm delivery within a recent Irish urban obstetric population. Spontaneous idiopathic preterm labor was the principle causative factor in 43% of all preterm deliveries, and represents the proportion of women for whom future therapeutic intervention may be of benefit.
©2008 by Walter de Gruyter Berlin New York
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- Congress Calendar
- Announcement
- Announcement
Artikel in diesem Heft
- Editorial
- Does globalization and change demand a different kind of perinatal research?
- Recommendations and guidelines for perinatal practice
- Intrauterine restriction (IUGR)
- Review article
- The role of antioxidant vitamins in hypertensive disorders of pregnancy
- Original articles – Obstetrics
- The fetus, not the mother, elicits maternal immunologic rejection: lessons from discordant dizygotic twin placentas
- Do risk factors for elective cesarean section differ from those of cesarean section during labor in low risk pregnancies?
- Obstetric antecedents for preterm delivery
- Post-delivery oxidative stress in women with preeclampsia or IUGR
- Evidence supporting proteolytic cleavage of insulin-like growth factor binding protein-1 (IGFBP-1) protein in amniotic fluid
- Original articles – Fetus
- Value of a single early third trimester fetal biometry for the prediction of birth weight deviations in a low risk population
- Comparison of six sonographic signs in the prenatal diagnosis of spina bifida
- Original articles – Newborn
- Relationships between umbilical cord arterial blood pH levels at delivery and Bayley Psychomotor Development Index scores in early childhood
- Head circumference and long-term outcome in small-for-gestational age infants
- Hypocalcemia is common in the first 48 h of life in ELBW infants
- Total body water in small- and appropriate- for gestational age newborns
- Below median birth weight in appropriate-for-gestational-age preterm infants as a risk factor for bronchopulmonary dysplasia
- Letter to the editor
- Congenital lupus erythematosus affecting both twins
- Obituary Gösta Rooth
- The death of Prof. Gösta Rooth
- Erratum
- Hematological profile of Korean very low birth weight infants
- Congress Calander
- Congress Calendar
- Announcement
- Announcement
