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Kinetic Study of Apo B100 Containing Lipoprotein Metabolism Using Amino Acids Labeled with Stable Isotopes: Methodological Aspects

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Published/Copyright: June 1, 2005
Clinical Chemistry and Laboratory Medicine (CCLM)
From the journal Volume 36 Issue 10

Abstract

Kinetic disturbances of lipoprotein metabolism are important to know for a better understanding of lipid diseases or effects of drugs. These kinetic aspects were previously studied with radioactive tracers. The ethical concerns related to these tracers can be now overcome at a reasonable cost with the new development of small bench top mass spectrometers and the increased production of stable isotope tracers. In this review, we will discuss some methodological aspects related to stable isotope tracers and the analysis of the data with non-compartmental or compartmental models.

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Published Online: 2005-06-01
Published in Print: 1998-10-13

Copyright © 1999 by Walter de Gruyter GmbH & Co. KG

Articles in the same Issue

  1. Kinetic Study of Apo B100 Containing Lipoprotein Metabolism Using Amino Acids Labeled with Stable Isotopes: Methodological Aspects
  2. Activated Immune System in Patients with Huntington's Disease
  3. Elevated Group 11 Phospholipase A2 Mass Concentration in Serum and Colonic Mucosa in Crohn's Disease
  4. Determination of pH in Human Erythrocytes. Sources of Systematic Error
  5. Rapid Molecular Diagnosis of Erythropoietic Protoporphyria among Swiss Patients
  6. Biochemical Evaluation of Oxidative Stress in Propylthiouracil Treated Hyperthyroid Patients. Effects of Vitamin C Supplementation
  7. Effect of Aminoguanidine on Erythrocyte Lipid Peroxiclation and Activities of Antioxidant Enzymes in Experimental Diabetes
  8. Normalizing Intermethod Free Triiodothyronine Patient Results: Need for Commutable Materials
  9. Evaluation of a Predictive Kinetic Procedure for the Enzymatic Measurement of Creatinine in Serum
  10. Pre-Evaluation and System Optimization of the Elecsys® Thyroid Electrochemiluminescence Immunoassays
  11. Validation of an Automated Enzyme Immunoassay for Interleukin-6 for Routine Clinical Use
  12. First Experience with the REMEDi HS Urine Benzodiazepine Assay
  13. Rapid Variations of the Free Prostate-Specific Antigen Fraction in Serum
  14. Are the Preanalytical Factors Underestimated in Clinical Studies?
  15. Book Review
https://doi.org/10.1515/CCLM.1998.131

Articles in the same Issue

  1. Kinetic Study of Apo B100 Containing Lipoprotein Metabolism Using Amino Acids Labeled with Stable Isotopes: Methodological Aspects
  2. Activated Immune System in Patients with Huntington's Disease
  3. Elevated Group 11 Phospholipase A2 Mass Concentration in Serum and Colonic Mucosa in Crohn's Disease
  4. Determination of pH in Human Erythrocytes. Sources of Systematic Error
  5. Rapid Molecular Diagnosis of Erythropoietic Protoporphyria among Swiss Patients
  6. Biochemical Evaluation of Oxidative Stress in Propylthiouracil Treated Hyperthyroid Patients. Effects of Vitamin C Supplementation
  7. Effect of Aminoguanidine on Erythrocyte Lipid Peroxiclation and Activities of Antioxidant Enzymes in Experimental Diabetes
  8. Normalizing Intermethod Free Triiodothyronine Patient Results: Need for Commutable Materials
  9. Evaluation of a Predictive Kinetic Procedure for the Enzymatic Measurement of Creatinine in Serum
  10. Pre-Evaluation and System Optimization of the Elecsys® Thyroid Electrochemiluminescence Immunoassays
  11. Validation of an Automated Enzyme Immunoassay for Interleukin-6 for Routine Clinical Use
  12. First Experience with the REMEDi HS Urine Benzodiazepine Assay
  13. Rapid Variations of the Free Prostate-Specific Antigen Fraction in Serum
  14. Are the Preanalytical Factors Underestimated in Clinical Studies?
  15. Book Review
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