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N-Benzoyl, L-Glutamic Acid as a Suitable Internal Standard for the Analysis of trans,trans-Muconic Acid in Human Urine by Liquid Chromatography
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Gilles Renom
Published/Copyright:
June 1, 2005
Abstract
Urinary trans,trans-muconic acid is a sensitive biomarker for low level benzene exposure. The method described by Ducos et al. (Int Arch Occup Environ Health 1990; 62:529–34) is commonly used for its determination. In this study, we demonstrate that N-benzoyl, L-glutamic acid added to urine samples is a suitable internal standard to control trans,trans-muconic acid recovery after solid phase extraction of urine and to compensate for variations which might occur during high-performance liquid chromatography analysis.
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Published Online: 2005-06-01
Published in Print: 1998-02-27
Copyright © 1998 by Walter de Gruyter GmbH & Co. KG
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Articles in the same Issue
- Genetic Approach for Insulin-Independent Diabetes Mellitus in Clinical Practice
- An Enzymatic Method for the Determination of Free Fatty Acids in Serum/Plasma
- Specificity of Cardiac Troponins I and T in Renal Disease
- Blood and Tissue Findings in the Diagnosis of Mesenteric Ischaemia: An Experimental study
- Fucosylation and Galactosylation of IgG Heavy Chains Differ between Acute and Remission Phases of Juvenile Chronic Arthritis
- Analytical Evaluation of an Improved Procedure for Measuring Thyrotropin
- Erroneous Monocyte and Neutrophil Counts with the Sysmex NE-1500 in Patients Recovering from Bone Marrow Aplasia
- N-Benzoyl, L-Glutamic Acid as a Suitable Internal Standard for the Analysis of trans,trans-Muconic Acid in Human Urine by Liquid Chromatography
- Acute Exogenous Elevation of Plasma Free Fatty Acids Does Not Influence the Plasma Magnesium Concentration
- Characterisation and Evaluation of External Quality Assessment Scheme Serum
- Need for Correct Estimates of Biological Variation: The Example of C-Reactive Protein
