On the Mechanism of Inhibition of Globin Chain Initiation by Pactamycin

Kapitel in diesem Buch

1. Frontmatter I
2. Preface IX
3. Contents XI
4. List of Participants of the Lipmann Symposium XVI
5. List of Contributors XXI
6. Opening Remarks
7. Welcome to Professor Lipmann 1
8. Welcome to the Max-Planck-Institut 5
9. Introduction
10. Dahlem in the Late Nineteen Twenties 7
11. Contributions
12. Cascade Control of E. coli Glutamine Synthetase 28
13. Structure and Biosynthesis of an Acidic Glycoprotein in a Bacterial Cell Envelope 40
14. Degradation of Thyrotropin Releasing Hormone (TRH). Its Inhibition by Pyroglu-His-OCH₃ and the Effect of the Inhibitor in Attempts to study the Biosynthesis of TRH 53
15. Amphibian Cells in Culture: An Approach to Metamorphosis 63
16. The Hexokinase-Mitochondrial Binding Theory of Insulin Action 77
17. N-Terminal Acetylation of Proteins, a Post-lnitiational Event 89
18. Why is Insect Immunity Interesting? 103
19. Energy Transduction in Membranes of Mycobacterium phlei 115
20. Control by Peptidyl-tRNA of Elongation Factor G Interaction with the Ribosome 131
21. A Cytoplasmic Function for the Polyadenylic Sequences of Messenger RNA 144
22. Purification and Biological Properties of a Plasminogen Activator Characteristic of Malignantly Transformed Cells 150
23. Interactions of Troponin Subunits Underlying Regulation of Muscle Contraction by Ca Ion: A Study on Hybrid Troponins 165
24. Studies on the Binding of Acylaminoacyl-Oligonucleotide to Rat Liver 60S Ribosomal Subunits and Its Participation in the Peptidyltransferase Reaction 179
25. Regulatory Phosphorylation of Purified Pig Liver Pyruvate Kinase 192
26. A Soluble Elongation Factor Required for Protein Synthesis with mRNA's other than Poly (U) 205
27. Variations in the Lactate Dehydrogenase Isoenzyme Pattern in Arteries 216
28. Biochemical Development of the Heart in Syrian Hamsters 225
29. On the Mechanism of Inhibition of Globin Chain Initiation by Pactamycin 237
30. The Ribosomal Binding Site of the Antibiotic Thiostrepton 250
31. tRNA Structures in Viral RNA Genomes 264
32. Remarks on the Acquisition of Active Quaternary Structure of Enzymes 277
33. Covalent Binding of Bilirubin to Agarose and Use of the Product for Affinity Chromatography of Serum Albumin 281
34. Transmitter Biochemistry of Single, Identified Neurons 298
35. Regulation of Apoferritin Biosynthesis in Rat Liver 308
36. High Lipoprotein Lipase Activity and Cardiovascular Disease 322
37. Gramicidin S-Synthetase: Active Form of the Multienzyme Complex is Undissociable by Sodium Dodecylsulfate 336
38. Studies on the Biosynthesis and Structure of Renal Glomerular Basement Membrane 345
39. Ribosomes and the Target Theory 359
40. Interrelation Between Tyrocidine Synthesis and Sporulation in Bacillus brevis 368
41. Intergeneric Complementation of RNA Polymerase Subunits 377
42. Studies on Liver Elongation Factor 1 384
43. Some Thoughts on the Regulation of Arginine Biosynthesis and its Relation to Biochemistry 399
44. Mechanism of the Cell Cycle in DNA Synthesis in Sea Urchin Embryos 404
45. Ribosome Metabolism in Starving Relaxed E. coli Cells 410
46. Subcellular Localization in the Ehrlich Ascites Cell of the Enzyme which Oxidizes Dihydroorotate to Orotate 422
47. Comparison of Polypeptide Chain Initiation Factors from Artemia salina and Rabbit Reticulocytes 435
48. Thiamine-Binding Protein of Escherichia coli 443
49. Photoaffinity Labelling of tRNA Binding Sites on E. coli Ribosomes 456
50. Identification of Central Transmitters with Electrically Stimulated Brain Slices 471
51. The Acetylation of Cysteine-281 in Glyceraldehyde-3- Phosphate Dehydrogenase by an S-S Transfer Reaction 487
52. Regulation of Elongation Factor G-Ribosomal GTPase Activity 499
53. Deoxynucleotide-Polymerizing Enzymes of Murine Myelomas 511
54. Properties and Functions of Ethanol-Potassium Chloride Extractable Proteins from 80S Ribosomes and their Interchangeability with the Bacterial Proteins L7/L12 524
55. Choline Acetytransferase: Reactions of the Active Site Sulfhydryl Group 534
56. Control of Gene Expression by E. coli Virus T7 547
57. Covalent Enzyme-Substrate Intermediates in Carboxyl Activation 564
58. The Role of Pantothenate in Citrate Lyase 575
59. Cleavage of Small DNAs with Restriction Nucleases 589
60. The Ribosomal and Nonribosomal Synthesis of Guanosine Polyphosphates 599
61. Phage f2 RNA Structure in Relation to Synthesis of Phage Proteins 610
62. Protein Kinases from Eukaryotic Organisms 623
63. The Interaction of Red Blood Cell Protein Factors with Cyclic AMP 636
64. On the Linkage and Recombination of Mitochondrial Genes 647
65. Determination of mRNA and 28 S RNA Turnover in Proliferating HeLa Cells 658
66. Annual Fritz Lipmann Lecture
67. Structures of Biotin Enzymes 671
68. Photographs 699
69. Backmatter 702