BIOKYBERNETIKA: Mathematics for Theory and Control in the Human and in Society

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BIOKYBERNETIKA

Mathematics for Theory and Control in the Human and in Society

Edited by: Jochen Mau , Sergey Mukhin , Guanyu Wang and Shuhua Xu

Language: English

Published/Copyright: 2025

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This book is in the series

Volume 9 | De Gruyter Series in Mathematics and Life Sciences

About this book

This book aims to engage “Young Science – Talented & Ambitious” for a lasting collaboration to advance holistic mathematical modeling of “how the body works” in variant surroundings. The book sets road signs to mathematics in body’s vital, physical, and cognitive functions, as well as to factors of health impact in person’s environmental and social settings. It showcases selected current research in mathematical and biological theory, mathematical models at molecular, organism, and population levels as well as engineering, imaging, and data sciences methodologies, including bio-informatics and machine learning applications. For overarching theory, evaluation of surrogate structures with category theory, multi-scale whole-body dynamics by separation of functional organization from cellular material as well as mathematical axioms matching classic principles of philosophy in traditional Chinese medicine are introduced. Interested are systems-oriented researchers in all sciences related to human health who seek new profile-shaping challenges in transdisciplinary collaboration.

You can find "BIOKYBERNETIKA II - Thermodynamics, Functional Physiology, Process Control, and Society Impact" here https://www.degruyterbrill.com/document/isbn/9783112216811/html

Holistic top-down systems perspective distances it from reductionist molecular bottom-up
Separating function from material permits investigation of dynamics and controls as in engineered systems
Integrates health factors into mathematical medicine

Author / Editor information

Jochen Mau, HHU, Germany; Sergey Mukhin, MSU, Russia; Guanyu Wang, CUHK, China; Shuhua Xu, Fudan, China.

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Frontmatter
I

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Prologue I
VII
Jochen Mau

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Prologue II
XI
Jochen Mau

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Prologue III
XIII
Jianhua Zhang

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Preface
XVII

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Overview
XIX
Jochen Mau

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Contents
XXXIII

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Part I: Theories
Part I-A: Overarching theory
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Introduction
1

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Universal axioms in classical Chinese philosophy
5
Yi Feng and Jochen Mau

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Category theory for structural characterization
15
Jochen Mau

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Axiomatic bipolar dynamics and their control
45
Jochen Mau

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Part I-B: Systems theories
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Introduction
75

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Stochastic formalization of agent-oriented systems
79
Sergey V. Bogomolov, Vyacheslav A. Sapozhnikov and Roman Yu. Yurmalnik

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Simplification of high-dimensional multitempo dynamic models
109
Lijun Zhang, Elena Shchepakina and Vladimir Sobolev

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Ideas of symmetry as a biophysical basis of system biomedicine
123
Vsevolod Tverdislov, Alla Sidorova, Olga Bagrova, Ekaterina Belova, Aleksey Lutsenko, Ekaterina Semenova, Denis Shpigun and Natalia Levashova

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Disorder of multiscale control
149
Shuchang Wang and Guanyu Wang

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Part II: Person’s life-sphere
Part II-A: Person’s biosphere
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Introduction
185

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Mutations as activators of biological evolutionary processes at population levels
189
Alla Sidorova, Natalia Levashova, Anastasya Garaeva, Vsevolod Tverdislov and Raul Argun

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Immunometabolism of T-cells in COVID-19
209
Jian Li, Junping Yin and Christian Kurts

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Part II-A.2: Body’s vital functions
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Introduction
245

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Structural modeling of vascular networks
249
Veronika S. Kopylova, Stanislav E. Boronovskiy and Yaroslav R. Nartsissov

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Mathematical modeling of AI application for the diagnosis of blood flow disorders
283
Egor V. Kochetov, Anna Ya. Bunicheva and Sergey I. Mukhin

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Modeling of glucose and insulin regulation within the framework of a self-consistent model of the cardiovascular system
303
Alexander Khrulenko, Kseniia Mysova and Anatoly Pokladyuk

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Hemodynamics in residual myocardial ischemia
319
Sergey Simakov, Timur Gamilov, Alexander Danilov, Philipp Kopylov, Peter Chomakhidze and Fuyou Liang

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The quasi-one-dimensional model of the lymph flow in the human lymphatic system
335
Anastasiia S. Mozokhina and Sergey I. Mukhin

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An integrate-and-fire mechanism for modeling rhythmicity in the neuroendocrine system
365
Alexander N. Churilov and John G. Milton

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Kinetic network modeling of the neuroendocrine hypothalamic-pituitary-adrenal axis dynamics with particular attention on the role of alcohol as a digestif
377
Ljiljana Kolar-Anić, Željko Čupić, Ana Stanojević, Stevan Maćešić, Milorad Anđelković and Vladana Vukojević

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Inflammation and immune response in atherosclerosis
393
Ghada Abi Younes, Wissam El Hajj, Nader El Khatib and Vitaly Volpert

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Part II-A.3: Body’s motor functions
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Introduction
423

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A magnetic resonance spectroscopy approach to quantitatively measure GABA and phosphorus level changes in the primary motor cortex elicited by transcranial direct current stimulation
427
Chang-Hoon Choi, Harshal Jayeshkumar Patel, N. Jon Shah and Ferdinand Binkofski

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Part II-A.4: Body’s operational functions
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Introduction
441

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The fermionic mind hypothesis–a category-theoretic verification of consciousness
445
Eva Déli

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Cross-task cognitive workload measurement based on the sample selection of the EEG data
459
Qi Wang, Xin Xie, Jianhua Zhang and Zhong Yin

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Part II-B: Person’s eco-sphere exposures
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Introduction
475

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The spread of SARS-CoV-2 in Russia and the evolution of the properties of the pathogen
479
Andrey N. Gerasimov

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Agent-based modeling of epidemic spread via kinetic Monte Carlo method
491
Rui Tang, Alexei G. Makeev and Natalia L. Semendyaeva

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Control of SARS-nCoV outbreaks in China 2020
513
Jochen Mau and Wenhua Tian

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Part II-B.2: Civilization
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Introduction
531

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Pesticide exposure: Toward holistic environmental modeling
535
Nadezda A. Vasilyeva and Artem A. Vladimirov

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Part II-C: Person’s sociosphere exposures
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Introduction
559

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Evolution of the health system in Shanghai, China, 2016–2020
563
Wenhua Tian

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Part III: Technologies
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Introduction
577

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Design-process automation using functional process blocks
581
Samuel Vogel

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Slow/fast dynamic models with applications to engineering problems
601
Sergei Sazhin, Elena Shchepakina and Vladimir Sobolev

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Part III-B: Information sciences
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Introduction
613

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Numerical modeling of medical ultrasound using the grid-characteristic method
617
Katerina Alexeevna Beklemysheva, Igor Borisovich Petrov, Evgeny Viktorovich Pyriaev and Alexey Viktorovich Vasyukov

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The direct and the inverse magnetic encephalography problem
635
Ivan P. Pakhnenko, Arthur I. Sabirov and Tatyana V. Zakharova

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Part III-C: Data-analytic sciences
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Introduction
653

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Assessing the bioequivalence of two different drugs with the same active ingredient
655
Margarita A. Dranitsyna, Victor K. Klimenko, Pavel V. Panov and Tatyana V. Zakharova

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Estimation of adjusted relative risks in log-binomial regression using the Bekhit–Schöpe–Wagenpfeil algorithm
665
Stefan Wagenpfeil, Jakob Schöpe and Adam Bekhit

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Part IV: Clinical medicine
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Introduction
679

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Finding optimal two-stage combined treatment protocols for a blood cancer model
681
Evgenii N. Khailov, Nikolay L. Grigorenko and Ellina V. Grigorieva

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Unraveling the mysteries: Mathematical perspectives on traditional Chinese medicine meridians
697
Wei Hu and Xiaoyu Tong

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Epilogue
721

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Index
723

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Publishing information

Pages and Images/Illustrations in book

eBook published on:

December 30, 2024

eBook ISBN:

9783111341996

Hardcover published on:

December 30, 2024

Hardcover ISBN:

9783111341972

Pages and Images/Illustrations in book

Front matter:

38

Main content:

736

Illustrations:

63

Coloured Illustrations:

175

Tables:

60

https://doi.org/10.1515/9783111341996

eBook ISBN: 9783111341996

Hardcover ISBN: 9783111341972

Keywords for this book

Multi-scale bio-mathematics; Theoretical physiology; Biomedical engineering; Information technology; Health-impact factors_x000D_

Audience(s) for this book

Theoretical and experimental research in systems-oriented mathematics, engineering, medicine, and all health-impact sciences

Safety & product resources

Manufacturer information:
Walter de Gruyter GmbH
Genthiner Straße 13
10785 Berlin
productsafety@degruyterbrill.com

BIOKYBERNETIKA

Overview

About this book

Author / Editor information

Topics

Table of contents

Frontmatter

Prologue I

Prologue II

Prologue III

Preface

Overview

Contents

Introduction

Universal axioms in classical Chinese philosophy

Category theory for structural characterization

Axiomatic bipolar dynamics and their control

Introduction

Stochastic formalization of agent-oriented systems

Simplification of high-dimensional multitempo dynamic models

Ideas of symmetry as a biophysical basis of system biomedicine

Disorder of multiscale control

Introduction

Mutations as activators of biological evolutionary processes at population levels

Immunometabolism of T-cells in COVID-19

Introduction

Structural modeling of vascular networks

Mathematical modeling of AI application for the diagnosis of blood flow disorders

Modeling of glucose and insulin regulation within the framework of a self-consistent model of the cardiovascular system

Hemodynamics in residual myocardial ischemia

The quasi-one-dimensional model of the lymph flow in the human lymphatic system

An integrate-and-fire mechanism for modeling rhythmicity in the neuroendocrine system

Kinetic network modeling of the neuroendocrine hypothalamic-pituitary-adrenal axis dynamics with particular attention on the role of alcohol as a digestif

Inflammation and immune response in atherosclerosis

Introduction

A magnetic resonance spectroscopy approach to quantitatively measure GABA and phosphorus level changes in the primary motor cortex elicited by transcranial direct current stimulation

Introduction

The fermionic mind hypothesis–a category-theoretic verification of consciousness

Cross-task cognitive workload measurement based on the sample selection of the EEG data

Introduction

The spread of SARS-CoV-2 in Russia and the evolution of the properties of the pathogen

Agent-based modeling of epidemic spread via kinetic Monte Carlo method

Control of SARS-nCoV outbreaks in China 2020

Introduction

Pesticide exposure: Toward holistic environmental modeling

Introduction

Evolution of the health system in Shanghai, China, 2016–2020

Introduction

Design-process automation using functional process blocks

Slow/fast dynamic models with applications to engineering problems

Introduction

Numerical modeling of medical ultrasound using the grid-characteristic method

The direct and the inverse magnetic encephalography problem

Introduction

Assessing the bioequivalence of two different drugs with the same active ingredient

Estimation of adjusted relative risks in log-binomial regression using the Bekhit–Schöpe–Wagenpfeil algorithm

Introduction

Finding optimal two-stage combined treatment protocols for a blood cancer model

Unraveling the mysteries: Mathematical perspectives on traditional Chinese medicine meridians

Epilogue

Index

Bibliographic data