Chapter 9 Recent advances in mesoporous silica nanoparticles research
-
Bhushan R. Rane
Abstract
Mesoporous silica materials came to light in the early 1990s when a new class of molecular sieves known as M41S was discovered. Greater surface area, mesoporous structure, biocompatibility, polymeric hybridizability, modifiability, and tunable pore size/diameter are among the remarkably intuitive properties of SNPs that are contributing to their growing potential applications, which include tumor targeting, solubility enhancement, tissue engineering, gene therapy, and diagnostic applications. Mesoporous nanoparticles (NPs) of silica come in many different forms including M41S, COK, SBA, KIT, and FDU. They are produced using a variety of techniques, such as chemical etching, sol-gel, template-assisted, and microwave-assisted. Over the past two decades, a vast amount of study has been conducted by numerous researchers. Also, a number of patents have been filed regarding the method of preparation and synthesis of NPs of mesoporous silica, and a number of clinical trials have been carried out in this field. This chapter compiles the significant advancements made in the last 20 years. Mesoporous silica nanoparticles for biomedical applications are being designed and developed, such as the possible therapy for various diseases, along with the work still needed in order to accomplish the clinical translation of these resources.
Abstract
Mesoporous silica materials came to light in the early 1990s when a new class of molecular sieves known as M41S was discovered. Greater surface area, mesoporous structure, biocompatibility, polymeric hybridizability, modifiability, and tunable pore size/diameter are among the remarkably intuitive properties of SNPs that are contributing to their growing potential applications, which include tumor targeting, solubility enhancement, tissue engineering, gene therapy, and diagnostic applications. Mesoporous nanoparticles (NPs) of silica come in many different forms including M41S, COK, SBA, KIT, and FDU. They are produced using a variety of techniques, such as chemical etching, sol-gel, template-assisted, and microwave-assisted. Over the past two decades, a vast amount of study has been conducted by numerous researchers. Also, a number of patents have been filed regarding the method of preparation and synthesis of NPs of mesoporous silica, and a number of clinical trials have been carried out in this field. This chapter compiles the significant advancements made in the last 20 years. Mesoporous silica nanoparticles for biomedical applications are being designed and developed, such as the possible therapy for various diseases, along with the work still needed in order to accomplish the clinical translation of these resources.
Chapters in this book
- Frontmatter I
- Contents V
- Contributing authors VII
- Chapter 1 Introduction to mesoporous silica nanoparticles (MSNs) 1
- Chapter 2 Synthesis of mesoporous silica nanoparticles 23
- Chapter 3 Characterization of mesoporous silica nanoparticles 55
- Chapter 4 Drug delivery using mesoporous silica nanoparticles (MSNs) 75
- Chapter 5 Catalytic applications of MSNs 97
- Chapter 6 Sensing and biosensing with mesoporous silica nanoparticles (MSNs) 119
- Chapter 7 Biomedical applications of MSNs 145
- Chapter 8 Environmental and sustainability applications 169
- Chapter 9 Recent advances in mesoporous silica nanoparticles research 187
- Chapter 10 Characterization techniques for advanced research 243
- Chapter 11 Industrial production and commercialization of MSNs 273
- Index 303
Chapters in this book
- Frontmatter I
- Contents V
- Contributing authors VII
- Chapter 1 Introduction to mesoporous silica nanoparticles (MSNs) 1
- Chapter 2 Synthesis of mesoporous silica nanoparticles 23
- Chapter 3 Characterization of mesoporous silica nanoparticles 55
- Chapter 4 Drug delivery using mesoporous silica nanoparticles (MSNs) 75
- Chapter 5 Catalytic applications of MSNs 97
- Chapter 6 Sensing and biosensing with mesoporous silica nanoparticles (MSNs) 119
- Chapter 7 Biomedical applications of MSNs 145
- Chapter 8 Environmental and sustainability applications 169
- Chapter 9 Recent advances in mesoporous silica nanoparticles research 187
- Chapter 10 Characterization techniques for advanced research 243
- Chapter 11 Industrial production and commercialization of MSNs 273
- Index 303
