Chapter 7 Biomedical applications of MSNs
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Sachin Kothawade
Abstract
Mesoporous silica nanoparticles (MSNs) have emerged as a versatile platform for a wide range of biomedical applications due to their unique properties, including high surface area, tunable pore size, and ease of functionalization. This chapter delves into the diverse applications of MSNs in the biomedical field, emphasizing their role in drug delivery, gene delivery, and diagnostic imaging. MSNs offer a promising solution for targeted and controlled drug delivery, enhancing the efficacy and reducing the side effects of therapeutic agents. In gene delivery, MSNs provide a safer and more efficient alternative to traditional vectors, facilitating advancements in gene therapy. Additionally, the use of MSNs in imaging and diagnostics enables the development of multifunctional theragnostic agents that combine therapeutic and diagnostic functions. The chapter also explores the therapeutic potential of MSNs beyond drug delivery, including their applications in photothermal and photodynamic therapies for cancer treatment. Furthermore, considerations regarding the biocompatibility and safety of MSNs are discussed, highlighting the importance of comprehensive toxicity studies and regulatory compliance.
Abstract
Mesoporous silica nanoparticles (MSNs) have emerged as a versatile platform for a wide range of biomedical applications due to their unique properties, including high surface area, tunable pore size, and ease of functionalization. This chapter delves into the diverse applications of MSNs in the biomedical field, emphasizing their role in drug delivery, gene delivery, and diagnostic imaging. MSNs offer a promising solution for targeted and controlled drug delivery, enhancing the efficacy and reducing the side effects of therapeutic agents. In gene delivery, MSNs provide a safer and more efficient alternative to traditional vectors, facilitating advancements in gene therapy. Additionally, the use of MSNs in imaging and diagnostics enables the development of multifunctional theragnostic agents that combine therapeutic and diagnostic functions. The chapter also explores the therapeutic potential of MSNs beyond drug delivery, including their applications in photothermal and photodynamic therapies for cancer treatment. Furthermore, considerations regarding the biocompatibility and safety of MSNs are discussed, highlighting the importance of comprehensive toxicity studies and regulatory compliance.
Chapters in this book
- Frontmatter I
- Contents V
- Contributing authors VII
- Chapter 1 Introduction to mesoporous silica nanoparticles (MSNs) 1
- Chapter 2 Synthesis of mesoporous silica nanoparticles 23
- Chapter 3 Characterization of mesoporous silica nanoparticles 55
- Chapter 4 Drug delivery using mesoporous silica nanoparticles (MSNs) 75
- Chapter 5 Catalytic applications of MSNs 97
- Chapter 6 Sensing and biosensing with mesoporous silica nanoparticles (MSNs) 119
- Chapter 7 Biomedical applications of MSNs 145
- Chapter 8 Environmental and sustainability applications 169
- Chapter 9 Recent advances in mesoporous silica nanoparticles research 187
- Chapter 10 Characterization techniques for advanced research 243
- Chapter 11 Industrial production and commercialization of MSNs 273
- Index 303
Chapters in this book
- Frontmatter I
- Contents V
- Contributing authors VII
- Chapter 1 Introduction to mesoporous silica nanoparticles (MSNs) 1
- Chapter 2 Synthesis of mesoporous silica nanoparticles 23
- Chapter 3 Characterization of mesoporous silica nanoparticles 55
- Chapter 4 Drug delivery using mesoporous silica nanoparticles (MSNs) 75
- Chapter 5 Catalytic applications of MSNs 97
- Chapter 6 Sensing and biosensing with mesoporous silica nanoparticles (MSNs) 119
- Chapter 7 Biomedical applications of MSNs 145
- Chapter 8 Environmental and sustainability applications 169
- Chapter 9 Recent advances in mesoporous silica nanoparticles research 187
- Chapter 10 Characterization techniques for advanced research 243
- Chapter 11 Industrial production and commercialization of MSNs 273
- Index 303
