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Chapter 1 Introduction to mesoporous silica nanoparticles (MSNs)

  • Anjali Bedse , Shilpa Raut , Varsha Tambe , Sachin Kothawade and Vishal Pande
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Mesoporous Silica Nanoparticles
This chapter is in the book Mesoporous Silica Nanoparticles

Abstract

In recent years, nanomedicine has emerged as a prominent field within nanotechnology, generating significant confidence in the field of biomedicine. Scientists are developing novel nanoparticles for diagnostic applications through the use of imaging technology as well as for therapeutic purposes by employing drug delivery methods. Mesoporous silica nanoparticles (MSNs) are commonly employed as drug delivery systems, considering their compatibility with living organisms, chemical properties, and high-temperature stability, enabling effective drug encapsulation and precise release. Inorganic MSNs are a recent addition to the manufacturing process, offering unique and remarkable properties among all existing nanoparticles. Additives can be employed during the production of MSNs to modify the characteristics of mesoporous materials, including their surface properties, pore size, drug capacity, and porosity. The dynamic surface enables the alteration of surface characteristics and the bonding of therapeutic chemicals. They are widely employed in diverse applications, such as diagnostics, targeted drug administration, biosensing, cellular uptake, and other areas in the field of biomedicine. This chapter highlights the application of MSNs as carriers for drug delivery. The unique composition, texture, and chemical characteristics of these nanosystems can create versatile systems that target diseased tissue and release cargo in response to stimuli.

Abstract

In recent years, nanomedicine has emerged as a prominent field within nanotechnology, generating significant confidence in the field of biomedicine. Scientists are developing novel nanoparticles for diagnostic applications through the use of imaging technology as well as for therapeutic purposes by employing drug delivery methods. Mesoporous silica nanoparticles (MSNs) are commonly employed as drug delivery systems, considering their compatibility with living organisms, chemical properties, and high-temperature stability, enabling effective drug encapsulation and precise release. Inorganic MSNs are a recent addition to the manufacturing process, offering unique and remarkable properties among all existing nanoparticles. Additives can be employed during the production of MSNs to modify the characteristics of mesoporous materials, including their surface properties, pore size, drug capacity, and porosity. The dynamic surface enables the alteration of surface characteristics and the bonding of therapeutic chemicals. They are widely employed in diverse applications, such as diagnostics, targeted drug administration, biosensing, cellular uptake, and other areas in the field of biomedicine. This chapter highlights the application of MSNs as carriers for drug delivery. The unique composition, texture, and chemical characteristics of these nanosystems can create versatile systems that target diseased tissue and release cargo in response to stimuli.

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