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1 Domino and one-pot syntheses of biologically active compounds using diphenylprolinol silyl ether
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Yujiro Hayashi
Abstract
The successful application of diphenylprolinol silyl ether, which is one of the widely used organocatalysts, to the synthesis of natural products and drugs, is described mostly focusing on the author’s results. The molecules that are explained in this paper are baclofen, telcagepant, oseltamivir, ABT-341, prostaglandins, estradiol, horsfiline and coerulescine.
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Abstract
The successful application of diphenylprolinol silyl ether, which is one of the widely used organocatalysts, to the synthesis of natural products and drugs, is described mostly focusing on the author’s results. The molecules that are explained in this paper are baclofen, telcagepant, oseltamivir, ABT-341, prostaglandins, estradiol, horsfiline and coerulescine.
Sie haben derzeit keinen Zugang zu diesem Inhalt.
Kapitel in diesem Buch
- Frontmatter I
- Preface V
- Contents VII
- Contributors List XIII
- 1 Domino and one-pot syntheses of biologically active compounds using diphenylprolinol silyl ether 1
- 2 Recent advances in reactions promoted by amino acids and oligopeptides 29
- 3 Amino-cinchona derivatives 85
- 4 Chiral imidazolidinones: A class of priviliged organocatalysts in stereoselective organic synthesis 177
- 5 Phase-transfer catalysis and the ion pair concept 197
- 6 Stereoselective organocascades: from fundamentals to recent developments 229
- 7 Basic principles of substrate activation through non-covalent bond interactions 263
- 8 Recent developments in stereoselective organocatalytic oxyfunctionalizations 293
- 9 Stereoselective synergystic organo photoredox catalysis with enamines and iminiums 331
- 10 Stereoselective organocatalysis and flow chemistry 365
- 11 Enantioselective organocatalytic approaches to active pharmaceutical ingredients – selected industrial examples 401
- Index 435
Kapitel in diesem Buch
- Frontmatter I
- Preface V
- Contents VII
- Contributors List XIII
- 1 Domino and one-pot syntheses of biologically active compounds using diphenylprolinol silyl ether 1
- 2 Recent advances in reactions promoted by amino acids and oligopeptides 29
- 3 Amino-cinchona derivatives 85
- 4 Chiral imidazolidinones: A class of priviliged organocatalysts in stereoselective organic synthesis 177
- 5 Phase-transfer catalysis and the ion pair concept 197
- 6 Stereoselective organocascades: from fundamentals to recent developments 229
- 7 Basic principles of substrate activation through non-covalent bond interactions 263
- 8 Recent developments in stereoselective organocatalytic oxyfunctionalizations 293
- 9 Stereoselective synergystic organo photoredox catalysis with enamines and iminiums 331
- 10 Stereoselective organocatalysis and flow chemistry 365
- 11 Enantioselective organocatalytic approaches to active pharmaceutical ingredients – selected industrial examples 401
- Index 435
