Abstract
The aim of chemical substitution is to replace hazardous chemicals with a less hazardous alternative in a certain product or process to make it safer for human health and the environment. While a lot has been done by researchers, industries and regulatory bodies on chemical substitution for safer products, very little has been reported in the field of safer processes. On the other hand, chemical substitution is one of the core principles of inherently safer design, a concept frequently used in the chemical industry for the prevention of major accidents. This work presents an analysis of implementing chemical substitution methodology for safer processes through inherently safer design. Chemical industries, nowadays, are frequently asked to phase out hazardous chemicals from their processes. This paper provides an insight into the issues and practicability of chemical substitution in processes with the help of case studies and a review of the existing frameworks of inherently safer design.
References
[1] UNITAR and the Sustainable Development Goals, SDGS & CHEMICALS AND WASTE, https://unitar.org/sustainable-development-goals/planet/our-portfolio/sdgs-chemicals-and-waste (accessed May 29, 2021).Suche in Google Scholar
[2] OECD Series on Risk Management, No. 26, Environment, Health and Safety, Environment Directorate, OECD ENV/JM/MONO(2013)24.Suche in Google Scholar
[3] S. R. Syeda, E. A. Khan, O. Padungwatanaroj, N. Kuprasertwong, A. K. Tula. Curr. Opin. Chem. Eng. 36, 100748 (2022), https://doi.org/10.1016/j.coche.2021.100748.Suche in Google Scholar
[4] 12 Principles of Green Chemistry, https://www.acs.org/content/acs/en/greenchemistry/principles/12-principles-of-green-chemistry.html (accessed May 29, 2021).Suche in Google Scholar
[5] T. A. Kletz. Process Saf. Prog. 15, 5 (1996), https://doi.org/10.1002/prs.680150105.Suche in Google Scholar
[6] K. Kidam, H. A. Sahak, M. H. Hassim, S. S. Shahlan, M. Hurme. J. Loss Prev. Process. Ind. 42, 47 (2016), https://doi.org/10.1016/j.jlp.2015.09.016.Suche in Google Scholar
[7] European Chemicals Agency, European Commission, https://echa.europa.eu/ (accessed May 29, 2021).Suche in Google Scholar
[8] U.S. Environmental Protection Agency (EPA), http://www.epa.gov/chemical-research/program-assisting-replacementindustrial-solvents-paris-iii (accessed May 29, 2021).Suche in Google Scholar
[9] Occupational Safety and Health Administration, http://www.osha.gov/dsg/safer_chemicals/why_transition.html (accessed May 29, 2021).Suche in Google Scholar
[10] HSE: Control of Major Accident Hazards Regulations. (2015), https://www.hse.gov.uk/comah/background/comah15.htm (accessed May 29, 2021).Suche in Google Scholar
[11] OSHA, Process safety management of highly hazardous chemicals, https://www.osha.gov/laws-regs/regulations/standardnumber/1910/1910.119 (accessed May 29, 2021).Suche in Google Scholar
[12] X. Gao, A. Raman, H. Hizaddin, M. Bello. J. Loss Prev. Process. Ind. 65, 104092 (2020), https://doi.org/10.1016/j.jlp.2020.104092.Suche in Google Scholar
[13] M. J. Jafari, H. Mohammadi, G. Reniers, M. Pouyakian, F. Nourai, S. A. Torabi, M. R. Miandashti. J. Loss Prev. Process. Ind. 52, 66 (2018), https://doi.org/10.1016/j.jlp.2018.01.013.Suche in Google Scholar
[14] Occupational Safety and Health Administration. List of Highly Hazardous Chemicals, Toxics and Reactives (Mandatory), https://www.osha.gov/lawsregs/regulations/standardnumber/1910/1910.119AppA.Suche in Google Scholar
[15] Occupational Safety and Health Administration. Toxic Industrial Chemicals (TICs) Guide, https://www.osha.gov/emergency-preparedness/guides/toxic-industrial-chemicals.Suche in Google Scholar
[16] T. Welton. Proc. R. Soc. A: Proc. Math. Phys. Eng. Sci. 471, 20150502 (2015), https://doi.org/10.1098/rspa.2015.0502.Suche in Google Scholar PubMed PubMed Central
[17] S. Fukuoka, M. Kawamura, K. Komiya, M. Tojo, H. Hachiya, K. Hasegawa, M. Aminaka, H. Okamoto, I. Fukawa, S. Konno. Green Chem. 5, 497 (2003), https://doi.org/10.1039/b304963a.Suche in Google Scholar
[18] S. J. Patel, D. Ng, M. S. Mannan. J. Loss Prev. Process. Ind. 23, 483 (2010), https://doi.org/10.1016/j.jlp.2010.03.002.Suche in Google Scholar
[19] A. M. Shariff, D. Zaini. J. Hazard. Mater. 182, 394 (2010), https://doi.org/10.1016/j.jhazmat.2010.06.046.Suche in Google Scholar PubMed
[20] P. Gangadharan, R. Singh, F. Cheng, H. H. Lou. Ind. Eng. Chem. Res. 52, 5921 (2013), https://doi.org/10.1021/ie303163y.Suche in Google Scholar
[21] S. Rathnayaka, F. Khan, P. Amyotte. Saf. Sci. 70, 438 (2014), https://doi.org/10.1016/j.ssci.2014.06.004.Suche in Google Scholar
[22] S. I. Ahmad, H. Hashim, M. H. Hassim. Process Saf. Environ. Protect. 92, 379 (2014), https://doi.org/10.1016/j.psep.2014.03.009.Suche in Google Scholar
[23] S. I. A. hmad, H. Hashim, M. H. Hassim. J. Loss Prev. Process. Ind. 42, 59 (2016), https://doi.org/10.1016/j.jlp.2015.09.018.Suche in Google Scholar
[24] M. Athar, A. M. Shariff, A. Buang, S. Nazir, H. Hermansyah, T. L. See. Process Saf. Environ. Protect. 128, 14 (2019b), https://doi.org/10.1016/j.psep.2019.05.033.Suche in Google Scholar
[25] F. Eljack, M.-K. Kazi, V. Kazantzi. J. Loss Prev. Process. Ind. 57, 280 (2019), https://doi.org/10.1016/j.jlp.2018.12.004.Suche in Google Scholar
[26] A. Crivellari, S. Bonvicini, A. Tugnoli, V. Cozzani. Process Saf. Environ. Protect. 148, 256 (2021), https://doi.org/10.1016/j.psep.2020.10.010.Suche in Google Scholar
[27] R. Rusli, A. M. Shariff. J. Loss Prev. Process. Ind. 23, 157 (2010), https://doi.org/10.1016/j.jlp.2009.07.005.Suche in Google Scholar
[28] R. Rusli, A. M. Shariff, F. I. Khan. Saf. Sci. 53, 61 (2013), https://doi.org/10.1016/j.ssci.2012.09.002.Suche in Google Scholar
[29] D. Song, E. S. Yoon, N. Jang. J. Loss Prev. Process. Ind. 54, 10 (2018), https://doi.org/10.1016/j.jlp.2018.02.006.Suche in Google Scholar
[30] S. Sultana, S. Haugen. J. Hazard. Mater. 421, 126590 (2022), https://doi.org/10.1016/j.jhazmat.2021.126590.Suche in Google Scholar PubMed
[31] G. Koller, U. Fischer, K. Hungerbühler. Process Saf. Environ. Protect. 79, 157 (2001), https://doi.org/10.1205/09575820150511939.3.Suche in Google Scholar
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Artikel in diesem Heft
- Frontmatter
- In this issue
- Editorial
- The virtual conference on chemistry and its applications, VCCA-2021, 9–13 August 2021
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- Hexabenzocoronene functionalized with antiaromatic S- and Se-core-modified porphyrins (isophlorins): comparison with the dyad with regular porphyrin
- Bonding analysis of the C2 precursor Me3E–C2–I(Ph)FBF3 (E = C, Si, Ge)
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- Degradation of o-, m-, p-cresol isomers using ozone in the presence of V2O5-supported Mn, Fe, and Ni catalysts
- The beginnings of chemistry: from ancient times until 1661
- Chemical substitution in processes for inherently safer design: pros and cons
- Experimental and theoretical study of the dye-sensitized solar cells using Hibiscus sabdariffa plant pigment coupled with polyaniline/graphite counter electrode
Artikel in diesem Heft
- Frontmatter
- In this issue
- Editorial
- The virtual conference on chemistry and its applications, VCCA-2021, 9–13 August 2021
- Conference papers
- Hexabenzocoronene functionalized with antiaromatic S- and Se-core-modified porphyrins (isophlorins): comparison with the dyad with regular porphyrin
- Bonding analysis of the C2 precursor Me3E–C2–I(Ph)FBF3 (E = C, Si, Ge)
- Supporting the fight against the proliferation of chemical weapons through cheminformatics
- Disinfecting activity of some diphenyltin(IV) benzoate derivative compounds
- HCV genotype-specific drug discovery through structure-based virtual screening
- ExcelAutomat 1.4: generation of supporting information
- Use of Circular Dichroism in the characterization of the fusion protein SARS-CoV-2 S protein (RBD)-hFc
- Experimental determination of activation rate constant and equilibrium constant for bromo substituted succinimide initiators for an atom transfer radical polymerization process
- Degradation of o-, m-, p-cresol isomers using ozone in the presence of V2O5-supported Mn, Fe, and Ni catalysts
- The beginnings of chemistry: from ancient times until 1661
- Chemical substitution in processes for inherently safer design: pros and cons
- Experimental and theoretical study of the dye-sensitized solar cells using Hibiscus sabdariffa plant pigment coupled with polyaniline/graphite counter electrode