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Synthesis and crystal structure of a tripeptide comprising a centrally placed non-coded aromatic γ-amino acid

  • Purak Das , Suven Das and Arpita Dutta EMAIL logo
Published/Copyright: September 17, 2024
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Zeitschrift für Kristallographie - Crystalline Materials
From the journal Zeitschrift für Kristallographie - Crystalline Materials Volume 239 Issue 9-10

Abstract

A protected tripeptide Boc-l-Leu-5-AIA-Aib-OMe was synthesized where 5-aminoisophthalic acid (5-AIA), a rigid non-coded aromatic γ-amino acid is incorporated as central residue. The single crystal X-ray diffraction study indicates that the peptide self-assembles into supramolecular sheet through intermolecular hydrogen bonding interaction N–H⋯O and π ··· π interaction.

Keywords: 5-aminoisophthalic acid; aromatic γ-amino acid; tripeptide; self-assembly
Corresponding author: Arpita Dutta, Department of Chemistry, Rishi Bankim Chandra Evening College, 24-Parganas (N), Pin-743165, Naihati, India, E-mail:

Funding source: SERB (DST), INDIA

Award Identifier / Grant number: TAR/2018/000228

Acknowledgments

AD acknowledges laboratory facilities at R. B. C. Evening College, Naihati.

  1. Informed consent: Informed consent was obtained from all individuals included in this study.

  2. Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  3. Competing interests: Authors state no conflict of interest.

  4. Research funding: PD is grateful to SERB (DST), India for fellowship [No. TAR/2018/000228].

  5. Ethical Approval: The local Institutional Review Board deemed the study exempt from review.

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Supplementary Material

This article contains supplementary material (https://doi.org/10.1515/zkri-2024-0095).

Received: 2024-07-13
Accepted: 2024-08-25
Published Online: 2024-09-17
Published in Print: 2024-10-28

© 2024 Walter de Gruyter GmbH, Berlin/Boston

Articles in the same Issue

  1. Frontmatter
  2. In this issue
  3. Inorganic Crystal Structures (Original Paper)
  4. Synthesis, characterization and structure-property relations in mullite-type Pb2(Pb1−xSn x )O4 solid solution
  5. Temperature-dependent diffraction studies on the stannides Sr3Rh4Sn4, Sr3Ir4Sn4 and Sr2.43Eu0.57Ir4Sn4
  6. Organic and Metalorganic Crystal Structures (Original Paper)
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https://doi.org/10.1515/zkri-2024-0095
Keywords for this article
5-aminoisophthalic acid; aromatic γ-amino acid; tripeptide; self-assembly

Articles in the same Issue

  1. Frontmatter
  2. In this issue
  3. Inorganic Crystal Structures (Original Paper)
  4. Synthesis, characterization and structure-property relations in mullite-type Pb2(Pb1−xSn x )O4 solid solution
  5. Temperature-dependent diffraction studies on the stannides Sr3Rh4Sn4, Sr3Ir4Sn4 and Sr2.43Eu0.57Ir4Sn4
  6. Organic and Metalorganic Crystal Structures (Original Paper)
  7. The crystal and molecular structure of (R)-sirtinol – C26H22N2O2 – a chemo-sensitive enhancer and ligand in metal complexes with important bio-inorganic applications
  8. Synthesis and structural characterization of supramolecular cocrystals of [(4-cyano-1-methylpyridinium)2-(18-crown-6)] diiodide
  9. 1-Nitronaphthalene, a non-OD, non-MDO polytype
  10. Synthesis and crystal structure of a tripeptide comprising a centrally placed non-coded aromatic γ-amino acid
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