Chemopreventive and hepatoprotective roles of adiponectin (SULF2 inhibitor) in hepatocelluar carcinoma

References

Akutsu, N., Yamamoto, H., Sasaki, S., Taniguchi, H., Arimura, Y., Imai, K., and Shinomura, Y. (2010). Association of glypican-3 expression with growth signaling molecules in hepatocellular carcinoma. World J. Gastroenterol. 16, 3521–3528.10.3748/wjg.v16.i28.3521Search in Google Scholar PubMed PubMed Central

Billottet, C., Elkhatib, N., Thiery, J.P., and Jouanneau, J. (2004). Targets of fibroblast growth factor 1 (FGF-1) and FGF-2 signaling involved in the invasive and tumorigenic behavior of carcinoma cells. Mol. Biol. Cell 15, 4725–4734.10.1091/mbc.e04-04-0336Search in Google Scholar PubMed PubMed Central

Bora, P.S., Kaliappan, S., Lyzogubov, V.V., Tytarenko, R.G., Thotakura, S., Viswanathan, T., and Bora, N.S. (2007). Expression of adiponectin in choroidal tissue and inhibition of laser induced choroidal neovascularization by adiponectin. FEBS Lett. 581, 1977–1982.10.1016/j.febslet.2007.04.024Search in Google Scholar PubMed

Bret, C., Moreaux, J., Schved, J.F., Hose, D., and Klein, B. (2011). SULFs in human neoplasia: implication as progression and prognosis factors. J. Transl. Med. 9, 72.10.1186/1479-5876-9-72Search in Google Scholar PubMed PubMed Central

Chen, K., Liu, M.L., Schaffer, L., Li, M., Boden, G., Wu, X., and Williams, K.J. (2010). Type 2 diabetes in mice induces hepatic overexpression of sulfatase 2, a novel factor that suppresses uptake of remnant lipoproteins. Hepatology 52, 1957–1967.10.1002/hep.23916Search in Google Scholar PubMed PubMed Central

Dalamaga, M. and Christodoulatos, G.S. (2015). Adiponectin as a biomarker linking obesity and adiposopathy to hematologic malignancies. Horm. Mol. Biol. Clin. Investig. 23, 5–2010.1515/hmbci-2015-0016Search in Google Scholar PubMed

Darweish, M.M., Abbas, A., Ebrahim, M.A., and Al-Gayyar, M.M. (2014). Chemopreventive and hepatoprotective effects of Epigallocatechin-gallate against hepatocellular carcinoma: role of heparan sulfate proteoglycans pathway. J. Pharm. Pharmacol. 66, 1032–1045.10.1111/jphp.12229Search in Google Scholar PubMed

Dong, S. and Wu, X.Z. (2010). Heparanase and hepatocellular carcinoma: promoter or inhibitor? World J. Gastroenterol. 16, 306–311.10.3748/wjg.v16.i3.306Search in Google Scholar PubMed PubMed Central

Elewa, M.A., Al-Gayyar, M.M., Schaalan, M.F., Abd El Galil, K.H., Ebrahim, M.A., and El-Shishtawy, M.M. (2015). Hepatoprotective and anti-tumor effects of targeting MMP-9 in hepatocellular carcinoma and its relation to vascular invasion markers. Clin. Exp. Metastasis. 32, 479–493.10.1007/s10585-015-9721-6Search in Google Scholar PubMed

Gao, Q. and Zheng, J. (2014). Adiponectin-induced antitumor activity on prostatic cancers through inhibiting proliferation. Cell Biochem. Biophys. 70, 461–465.10.1007/s12013-014-9941-4Search in Google Scholar PubMed

Gonzales, M., Mitsumori, L.M., Kushleika, J.V., Rosenfeld, M.E., and Krishnan, K.M. (2010). Cytotoxicity of iron oxide nanoparticles made from the thermal decomposition of organometallics and aqueous phase transfer with Pluronic F127. Contrast Media Mol. Imaging 5, 286–293.10.1002/cmmi.391Search in Google Scholar

Grivennikov, S.I., Greten, F.R., and Karin, M. (2010). Immunity, inflammation, and cancer. Cell 140, 883–899.10.1016/j.cell.2010.01.025Search in Google Scholar

Hadler-Olsen, E., Winberg, J.O., and Uhlin-Hansen, L. (2013).Matrix metalloproteinases in cancer: their value as diagnostic and prognostic markers and therapeutic targets. Tumour Biol. 34, 2041–2051.10.1007/s13277-013-0842-8Search in Google Scholar

Hah, N.and Lee, S.T. (2003). An absolute role of the PKC-dependent NF-κB activation for induction of MMP-9 in hepatocellular carcinoma cells. Biochem Biophys. Res. Commun. 305, 428–433.10.1016/S0006-291X(03)00788-5Search in Google Scholar

Huang, X., Ji, J., Xue, H., Zhang, F., Han X., Cai, Y., Zhang, J., and Ji, G. (2012). Fascin and cortactin expression is correlated with a poor prognosis in hepatocellular carcinoma. Eur. J. Gastroenterol. Hepatol. 24, 633–639.10.1097/MEG.0b013e3283515a18Search in Google Scholar PubMed

Lai, J.P., Sandhu, D.S., Yu, C., Han, T., Moser, C.D., Jackson, K.K., Guerrero, R.B., Aderca, I., Isomoto, H., Garrity-Park, M.M., et al. (2008). Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma. Hepatology 47, 1211–1222.10.1002/hep.22202Search in Google Scholar PubMed PubMed Central

Lai, J.P., Oseini, A.M., Moser, C.D., Yu, C., Elsawa, S.F., Hu, C., Nakamura, I., Han, T., Aderca, I., Isomoto, H., et al. (2010). The oncogenic effect of sulfatase 2 in human hepatocellular carcinoma is mediated in part by glypican 3-dependent Wnt activation. Hepatology 52, 1680–1689.10.1002/hep.23848Search in Google Scholar PubMed PubMed Central

Lambaerts, K., Wilcox-Adelman, S.A., and Zimmermann, P. (2009). The signaling mechanisms of syndecan heparan sulfate proteoglycans. Curr. Opin. Cell Biol. 21, 662–669.10.1016/j.ceb.2009.05.002Search in Google Scholar PubMed PubMed Central

Lee, J. and Lim, K.T. (2012). Activity of tumor necrosis factor-α blocked by phytoglycoprotein (38 kDa) at initiation stage in N-nitrosodiethylamine-induced ICR mice. Mol. Cell Biochem. 362, 177–186.10.1007/s11010-011-1140-7Search in Google Scholar PubMed

Molica, S., Digiesi, G., Vacca, A., Mirabelli, R., Todoerti, K., Battaglia, C., Morabito, F., Neri, A., and Ribatti, D. (2009). Does adiponectin act as an antiangiogenic factor in B-cell chronic lymphocytic leukemia? Adv. Hematol. 2009, 287974.Search in Google Scholar

Morimoto-Tomita, M., Uchimura, K., Werb, Z., Hemmerich, S., and Rosen, S.D. (2002). Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans. J. Biol. Chem. 277, 49175–49185.10.1074/jbc.M205131200Search in Google Scholar PubMed PubMed Central

Niu, K., Asada, M., Okazaki, T., Yamanda, S., Ebihara, T., Guo, H., Zhang, D., Nagatomi, R., Arai, H., Kohzuki, M., et al. (2012). Adiponectin pathway attenuates malignant mesothelioma cell growth. Am. J. Respir. Cell Mol. Biol. 46, 515–523.10.1165/rcmb.2011-0068OCSearch in Google Scholar

Ornitz, D.M. (2000). FGFs, heparan sulfate and FGFRs: complex interactions essential for development. Bioessays 22, 108–112.10.1002/(SICI)1521-1878(200002)22:2<108::AID-BIES2>3.0.CO;2-MSearch in Google Scholar

Powell, W.C. and Matrisian, L.M. (1996). Complex roles of matrix metalloproteinases in tumor progression. Curr. Top Microbiol. Immunol. 213, 1–21.10.1007/978-3-642-61107-0_1Search in Google Scholar

Pye, D.A., Vives, R.R., Hyde, P., and Gallagher, J.T. (2000). Regulation of FGF-1 mitogenic activity by heparan sulfate oligosaccharides is dependent on specific structural features: differential requirements for the modulation of FGF-1 and FGF-2. Glycobiology 10, 1183–1192.10.1093/glycob/10.11.1183Search in Google Scholar

Simionescu, C., Margaritescu, C., Stepan, A., Georgescu, C.V., Niculescu, M., and Muntean, M. (2010). The utility of p16, E-cadherin and Ki67 in cervical squamous intraepithelial lesions diagnosis. Rom. J. Morphol. Embryol. 51, 621–626.Search in Google Scholar

Stigliano, I., Puricelli, L., Filmus, J., Sogayar, M.C., Bal de Kier Joffe, E., and Peters, M.G. (2009). Glypican-3 regulates migration, adhesion and actin cytoskeleton organization in mammary tumor cells through Wnt signaling modulation. Breast Cancer Res. Treat. 114, 251–262.10.1007/s10549-008-0009-2Search in Google Scholar

Tayel, A., Abd El Galil, K.H., Ebrahim, M.A., Ibrahim, A.S., El-Gayar, A.M., and Al-Gayyar, M.M. (2014a). Suramin inhibits hepatic tissue damage in hepatocellular carcinoma through deactivation of heparanase enzyme. Eur. J. Pharmacol. 728, 151–160.10.1016/j.ejphar.2014.02.001Search in Google Scholar

Tayel, A., Ebrahim, M.A., Ibrahim, A.S., El-Gayar, A.M., and Al-Gayyar, M.M. (2014b). Cytotoxic effects of suramin against HepG2 cells through activation of intrinsic apoptotic pathway. J. BUON 19, 1048–1054.Search in Google Scholar

Wang, J., Shao, M., Liu, M., Peng, P., Li, L., Wu, W., Wang, L., Duan, F., Zhang, M., Song, S., et al. (2015). PKCalpha promotes generation of reactive oxygen species via DUOX2 in hepatocellular carcinoma. Biochem Biophys. Res. Commun. 463, 839–845.10.1016/j.bbrc.2015.06.021Search in Google Scholar

Wu, J. and Zhu, A.X. (2011). Targeting insulin-like growth factor axis in hepatocellular carcinoma. J. Hematol. Oncol. 4, 30.10.1186/1756-8722-4-30Search in Google Scholar

Wu, T.T., Hsieh, Y.H., Wu, C.C., Hsieh, Y.S., Huang, C.Y., and Liu, J.Y. (2007). Overexpression of protein kinase Cα mRNA in human hepatocellular carcinoma: a potential marker of disease prognosis. Clin. Chim. Acta 382, 54–58.10.1016/j.cca.2007.03.018Search in Google Scholar

Yang, X., Qiao, D., Meyer, K., and Friedl, A. (2009). Signal transducers and activators of transcription mediate fibroblast growth factor-induced vascular endothelial morphogenesis. Cancer Res. 69, 1668–1677.10.1158/0008-5472.CAN-07-6385Search in Google Scholar

Yang, J.D., Sun, Z., Hu, C., Lai, J., Dove, R., Nakamura, I., Lee, J.S., Thorgeirsson, S.S., Kang, K.J., Chu, I.S., et al. (2011). Sulfatase 1 and sulfatase 2 in hepatocellular carcinoma: associated signaling pathways, tumor phenotypes, and survival. Genes Chromosomes Cancer 50, 122–135.10.1002/gcc.20838Search in Google Scholar PubMed PubMed Central

Zaghloul, R., Al-Gayyar, M., El-Shishtawy, M., and Ebrahim, M. (2013). Cytotoxic effects of antiglypican-3 against HepG2 cell lines. J. App. Pharm. Sci. 3, 31–35.Search in Google Scholar

Zaghloul, R.A., El-Shishtawy, M.M., El Galil, K.H., Ebrahim, M.A., Metwaly, A.A., and Al-Gayyar, M.M. (2015). Evaluation of antiglypican-3 therapy as a promising target for amelioration of hepatic tissue damage in hepatocellular carcinoma. Eur. J. Pharmacol. 746, 353–362.10.1016/j.ejphar.2014.11.008Search in Google Scholar PubMed

Zhang, R., Wu, J., Liu, D., Shan, H., and Zhang, J. (2013). Anti-inflammatory effect of full-length adiponectin and proinflammatory effect of globular adiponectin in esophageal adenocarcinoma cells. Oncol. Res. 21, 15–21.10.3727/096504013X13786659070235Search in Google Scholar PubMed

Zhang, W., Shu, C., Li, Q., Li, M., and Li, X. (2015). Adiponectin affects vascular smooth muscle cell proliferation and apoptosis through modulation of the mitofusin-2-mediated Ras-Raf-Erk1/2 signaling pathway. Mol. Med. Rep. 12, 4703–4707.10.3892/mmr.2015.3899Search in Google Scholar PubMed