Abstract
Wernicke’s encephalopathy (WE) is a rare life-threatening complication following severe hyperemesis gravidarum. Early recognition of this condition and prompt thiamine administration is the key to preventing devastating sequelae. We report a successful delivery of a small-for-gestational-age (SGA) baby by a patient with WE and thyrotoxicosis in pregnancy.
Author Statement
Research funding: None.
Conflict of interest: The authors declare that there is no conflict of interest.
Informed consent: Not applicable.
Ethical approval: The conducted research is not related to either human or animal use.
References
1. Galvin R, Bråthen G, Ivashynka A, Hillbom M, Tanasescu R, Leone MA. EFNS guidelines for diagnosis, therapy and prevention of Wernicke encephalopathy. Eur J Neurol 2010;17:1408–18.10.1111/j.1468-1331.2010.03153.xSearch in Google Scholar PubMed
2. Chiossi G, Neri I, Cavazzuti M, Basso G, Facchinetti F. Hyperemesis gravidarum complicated by Wernicke encephalopathy: background, case report, and review of the literature. Obstet Gynecol Surv 2006;61:255–68.10.1097/01.ogx.0000206336.08794.65Search in Google Scholar PubMed
3. Selitsky T, Chandra P, Schiavello HJ. Wernicke’s encephalopathy with hyperemesis and ketoacidosis. Obstet Gynecol 2006;107(2 Part 2):486–90.10.1097/01.AOG.0000172373.41828.8aSearch in Google Scholar PubMed
4. Togay-Isikay C, Yigit A, Mutluer N. Wernicke’s encephalopathy due to hyperemesis gravidarum: an under-recognised condition. Aust N Z J Obstet Gynaecol 2001;41:453–6.10.1111/j.1479-828X.2001.tb01330.xSearch in Google Scholar PubMed
5. Sullivan EV, Pfefferbaum A. Neuroimaging of the Wernicke– Korsakoff syndrome. Alcohol Alcohol 2009;44:155–65.10.1093/alcalc/agn103Search in Google Scholar PubMed PubMed Central
6. Thomson AD, Guerrini I, Marshall EJ. Wernicke’s encephalopathy: role of thiamine. Pract Gastroenterol 2009;23:21–30.Search in Google Scholar
7. Martin PR. Molecular mechanisms of thiamine utilization. Curr Mol Med 2001;1:197–207.10.2174/1566524013363870Search in Google Scholar PubMed
8. Veenendaal MV, van Abeelen AF, Painter RC, van der Post JA, Roseboom TJ. Consequences of hyperemesis gravidarum for offspring: a systematic review and meta-analysis. Br J Obstet Gynaecol 2011;118:1302–13.10.1111/j.1471-0528.2011.03023.xSearch in Google Scholar PubMed
9. Butterworth RF. Maternal thiamine deficiency. A factor in Intrauterine Growth Retardation? Ann N Y Acad Sci 1993; 678:325–9.10.1111/j.1749-6632.1993.tb26135.xSearch in Google Scholar PubMed
©2017 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Long-term dutasteride therapy in men with benign prostatic hyperplasia alters glucose and lipid profiles and increases severity of erectile dysfunction
- Differential modulation of innate immune response by epinephrine and estradiol
- Association of transient hyperthyroidism and severity of hyperemesis gravidarum
- Effects of interleukin-1 receptor antagonist (IL-1Ra) gene 86 bp VNTR polymorphism on recurrent pregnancy loss: a case-control study
- Morning sickness of pregnancy: more than meets the eye
Articles in the same Issue
- Long-term dutasteride therapy in men with benign prostatic hyperplasia alters glucose and lipid profiles and increases severity of erectile dysfunction
- Differential modulation of innate immune response by epinephrine and estradiol
- Association of transient hyperthyroidism and severity of hyperemesis gravidarum
- Effects of interleukin-1 receptor antagonist (IL-1Ra) gene 86 bp VNTR polymorphism on recurrent pregnancy loss: a case-control study
- Morning sickness of pregnancy: more than meets the eye