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Vanishing Lung Syndrome

  • Samer Al Hadidi und Rupal Shastri
Veröffentlicht/Copyright: 1. August 2017

A 39-year-old man presented with a 1-year history of dyspnea on exertion and a single episode of hemoptysis. Medical history was also significant for 15-pack-per-year cigarette use and mild intermittent asthma. Physical examination revealed diffuse bilateral wheezing and decreased air entry with hyperresonant percussion at the right lower lung. Laboratory results were normal. Chest radiograph (image A, arrow) demonstrated a giant right pulmonary bulla, supporting the diagnosis of vanishing lung syndrome. Partial right lung lobectomy was performed 8 months later, and a chest radiograph showed resolution of the bulla (image B, arrow).

Vanishing lung syndrome is a chronic progressive condition. It is defined as bullae occupying at least one-third of the hemithorax.1 Risk factors include tobacco use, male sex, α-1-antitrypsin deficiency, and marijuana use.2-3 Tension pneumothorax is a potentially life-threatening complication. Although bullectomy is the treatment of choice, indications for surgical intervention should be individually assessed.4


From the Hurley Medical Center (Dr Al Hadidi) in Flint, Michigan, and Michigan State University (Dr Al Hadidi and Dr Shastri) in East Lansing.
Financial Disclosures: None reported.
Support: None reported.

*Address correspondence to Samer Al Hadidi, MD, MS, 2 Hurley Plaza, Suite 212, Flint, MI 48503-5905. E-mail:


References

1. Sharma N , JustaniahAM, KanneJP, GurneyJW, MohammedTL. Vanishing lung syndrome (giant bullous emphysema): CT findings in 7 patients and a literature review. J Thorac Imaging. 2009;24(3):227-230. doi:10.1097/RTI.0b013e31819b9f2aSuche in Google Scholar

2. Hii SW , TamJD, ThompsonBR, NaughtonMT. Bullous lung disease due to marijuana. Respirology. 2008;13(1):122-127. doi:10.1111/j.1440-1843.2007.01186.xSuche in Google Scholar

3. Hutchison DC , CooperD; British Thoracic Society. Alpha-1-antitrypsin deficiency: smoking, decline in lung function and implications for therapeutic trials. Respir Med. 2002;96(11):872-880.10.1053/rmed.2002.1381Suche in Google Scholar

4. Palla A , DesideriM, RossiG, et al. Elective surgery for giant bullous emphysema: a 5-year clinical and functional follow-up. Chest. 2005;128(4):2043-2050. doi:10.1378/chest.128.4.2043Suche in Google Scholar

Received: 2017-01-12
Accepted: 2017-01-19
Published Online: 2017-08-01
Published in Print: 2017-08-01

© 2017 American Osteopathic Association

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Heruntergeladen am 19.9.2025 von https://www.degruyterbrill.com/document/doi/10.7556/jaoa.2017.106/html
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