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Model of the human endocrine system regulatory network. Mechanisms and equations

  • A. A. Romanyukha
Veröffentlicht/Copyright: 13. August 2007
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Russian Journal of Numerical Analysis and Mathematical Modelling
Aus der Zeitschrift Band 22 Heft 3

This paper is devoted to the construction of a mathematical model of the endocrine system regulatory network. The model describes interdependence between the concentrations of forty-five hormones, carrier proteins, their complexes, and several physiological parameters. The integrated network including six endocrine subsystems or axes (somatotropic, gonadotropic, thyroid, hypothalamicpituitary-adrenal axis (HPA axis), mineral-corticoid and the axis of calcium homeostasis) is described. The model can be applied to the investigation of development, aging, long-term adaptation and approaches to correction of unfavorable dynamics of these complex physiological processes.

Published Online: 2007-08-13
Published in Print: 2007-07-20

Copyright 2007, Walter de Gruyter

Heruntergeladen am 17.9.2025 von https://www.degruyterbrill.com/document/doi/10.1515/rnam.2007.22.3.233/html
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