Abstract
The neurophysiological basis of consciousness is still unknown and one of the most challenging questions in the field of neuroscience and related disciplines. We propose that consciousness is characterized by the maintenance of mental representations of internal and external stimuli for the execution of cognitive operations. Consciousness cannot exist without working memory, and it is likely that consciousness and working memory share the same neural substrates. Here, we present a novel psychological and neurophysiological framework that explains the role of consciousness for cognition, adaptive behavior, and everyday life. A hypothetical architecture of consciousness is presented that is organized as a system of operation and storage units named platforms that are controlled by a consciousness center (central executive/online platform). Platforms maintain mental representations or contents, are entrusted with different executive functions, and operate at different levels of consciousness. The model includes conscious-mode central executive/online and mental time travel platforms and semiconscious steady-state and preconscious standby platforms. Mental representations or contents are represented by neural circuits and their support cells (astrocytes, oligodendrocytes, etc.) and become conscious when neural circuits reverberate, that is, fire sequentially and continuously with relative synchronicity. Reverberatory activity in neural circuits may be initiated and maintained by pacemaker cells/neural circuit pulsars, enhanced electronic coupling via gap junctions, and unapposed hemichannel opening. The central executive/online platform controls which mental representations or contents should become conscious by recruiting pacemaker cells/neural network pulsars, the opening of hemichannels, and promoting enhanced neural circuit coupling via gap junctions.
Author contribution: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: None declared.
Conflict of interest statement: The authors declare no conflicts of interest regarding this article.
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© 2020 Walter de Gruyter GmbH, Berlin/Boston
Artikel in diesem Heft
- Frontmatter
- Circulating microparticles in patients after ischemic stroke: a systematic review and meta-analysis
- Efficacy and safety of endovascular treatment for patients with acute intracranial atherosclerosis–related posterior circulation stroke: a systematic review and meta-analysis
- Neuroprotection of hypoxic/ischemic preconditioning in neonatal brain with hypoxic-ischemic injury
- Treatment for mitochondrial diseases
- The role of melatonin and its analogues in epilepsy
- Gut microbiota on gender bias in autism spectrum disorder
- BDNF and nicotine dependence: associations and potential mechanisms
- Brain metabolic DNA: recent evidence for a mitochondrial connection
- Channels to consciousness: a possible role of gap junctions in consciousness
Artikel in diesem Heft
- Frontmatter
- Circulating microparticles in patients after ischemic stroke: a systematic review and meta-analysis
- Efficacy and safety of endovascular treatment for patients with acute intracranial atherosclerosis–related posterior circulation stroke: a systematic review and meta-analysis
- Neuroprotection of hypoxic/ischemic preconditioning in neonatal brain with hypoxic-ischemic injury
- Treatment for mitochondrial diseases
- The role of melatonin and its analogues in epilepsy
- Gut microbiota on gender bias in autism spectrum disorder
- BDNF and nicotine dependence: associations and potential mechanisms
- Brain metabolic DNA: recent evidence for a mitochondrial connection
- Channels to consciousness: a possible role of gap junctions in consciousness