Abstract
According to the World Health Organization (WHO), viral diseases continue to rise, and pose a significant public health problem. Novel coronavirus disease (COVID-19) is an infectious disease caused by SARS-CoV-2. The pathogenesis and clinical manifestations of COVID-19 is close to Amraz-e-Wabai (epidemic diseases) which was described by Hippocrates, Galen, Aristotle, Razes, Haly Abbas, Avicenna, Jurjani etc. Presently, there is no specific or challenging treatment available for COVID-19. Renowned Unani Scholars recommended during epidemic situation to stay at home, and fumigate the shelters with aromatics herbs like Ood kham (Aquilaria agallocha Roxb.), Kundur (Boswellia serrata Roxb), Kafoor (Cinnamomum camphora L.), Sandal (Santalum album L), Hing (Ferula foetida L.) etc. Use of specific Unani formulations are claimed effective for the management of such epidemic or pandemic situation like antidotes (Tiryaqe Wabai, Tiryaqe Arba, Tiryaqe Azam, Gile Armani), Herbal Decoction (Joshandah), along with Sharbate Khaksi, Habbe Bukhar, Sharbate Zanjabeel, Khamira Marwareed, Jawarish Jalinus, and Sirka (vinegar). Such drugs are claimed for use as antioxidant, immunomodulatory, cardiotonic, and general tonic actions. The study enumerates the literature regarding management of epidemics in Unani medicine and attempts to look the same in the perspective of COVID-19 prevention and management.
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Research funding: There is no financial support in this study.
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Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
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Competing interests: The authors declare that they have no competing interests.
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Informed consent: Not applicable.
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Ethical approval: Not applicable.
References
1. Shereen, MA, Khan, S, Kazmi, A, Bashir, N, Siddique, R. COVID-19 infection: origin, transmission, and characteristics of human coronaviruses. J Adv Res 2020;24:91–8. https://doi.org/10.1016/j.jare.2020.03.005.Suche in Google Scholar
2. Rothan, HA, Byrareddy, SN. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J Autoimmun 2020;109:102433. https://doi.org/10.1016/j.jaut.2020.102433.Suche in Google Scholar
3. Cucinotta, D, Vanelli, M. WHO declares COVID-19 a pandemic. Acta Biomed 2020;91:157–60. https://doi.org/10.23750/abm.v91i1.9397.Suche in Google Scholar
4. Tian, S, Hu, N, Lou, J, Chen, K, Kang, X, Xiang, Z, et al.. Characteristics of COVID-19 infection in Beijing. J Infect 2020;80:401–6. https://doi.org/10.1016/j.jinf.2020.02.018.Suche in Google Scholar
5. Ruan, S. Likelihood of survival of coronavirus disease 2019. Lancet Infect Dis 2020;20:630–31.10.1016/S1473-3099(20)30257-7Suche in Google Scholar
6. Chan, JF, Yuan, S, Kok, KH, To, KK, Chu, H, Yang, J, et al.. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet 2020;395:514–23. https://doi.org/10.1016/S0140-6736(20)30154-9.Suche in Google Scholar
7. Lathabhavan, R, Griffiths, M. First case of student suicide in India due to the COVID-19 education crisis: a brief report and preventive measures. Asian J Psychiatr 2020;53:102202. https://doi.org/10.1016/j.ajp.2020.102202.Suche in Google Scholar PubMed PubMed Central
8. Jalava, K. First respiratory transmitted food borne outbreak? Int J Hyg Environ Health 2020;226:113490. https://doi.org/10.1016/j.ijheh.2020.113490.Suche in Google Scholar PubMed PubMed Central
9. Brüssow, H. The novel coronavirus–a snapshot of current knowledge. Microb Biotechnol 2020;13:607–12. https://doi.org/10.1111/1751-7915.13557.Suche in Google Scholar PubMed PubMed Central
10. Mackenzie, JS, Smith, DW. COVID-19: a novel zoonotic disease caused by a coronavirus from China: what we know and what we don’t. Microbiol Aust 2020;41:45–50. https://doi.org/10.1071/MA20013.Suche in Google Scholar PubMed PubMed Central
11. Li, C, Ji, F, Wang, L, Hao, J, Dai, M, Liu, Y, et al.. Asymptomatic and human-to-human transmission of SARS-CoV-2 in a 2-family cluster, Xuzhou, China. Emerg Infect Dis 2020;26:1626–8https://doi.org/10.3201/eid2607.200718.Suche in Google Scholar
12. Yong, SE, Anderson, DE, Wei, WE, Pang, J, Chia, WN, Tan, CW, et al.. Connecting clusters of COVID-19: an epidemiological and serological investigation. Lancet Infect Dis 2020;20:809–15https://doi.org/10.1016/S1473-3099(20)30273-5.Suche in Google Scholar
13. Zowalaty, ME, Jarhult, JD. From SARS to COVID-19: a previously unknown SARS-related coronavirus (SARS-CoV-2) of pandemic potential infecting humans–Call for a One Health approach. Int J One Health 2020;9:10–16. https://doi.org/10.1016/j.onehlt.2020.100124.Suche in Google Scholar PubMed PubMed Central
14. Ahmed, W, Angel, N, Edson, J, Bibby, K, Bivins, A, O’Brien, JW, et al.. First confirmed detection of SARS-CoV-2 in untreated wastewater in Australia: a proof of concept for the wastewater surveillance of COVID-19 in the community. Sci Total Environ 2020:138764.10.1016/j.scitotenv.2020.138764Suche in Google Scholar PubMed PubMed Central
15. Zhai, P, Ding, Y, Wu, X, Long, J, Zhong, Y, Li, Y. The epidemiology, diagnosis and treatment of COVID-19. Int J Antimicrob Agents 2020:105955.10.1016/j.ijantimicag.2020.105955Suche in Google Scholar PubMed PubMed Central
16. Lauer, SA, Grantz, KH, Bi, Q, Jones, FK, Zheng, Q, Meredith, HR, et al.. The incubation period of coronavirus disease 2019 (COVID-19) from publicly reported confirmed cases: estimation and application. Ann Intern Med 2020;172:577–82https://doi.org/10.7326/M20-0504.Suche in Google Scholar PubMed PubMed Central
17. Hussain, A, Bhowmik, B, do Vale Moreira, NC. COVID-19 and diabetes: knowledge in progress. Diabetes Res Clin Pract 2020:108142.10.1016/j.diabres.2020.108142Suche in Google Scholar PubMed PubMed Central
18. Han, Y, Jiang, M, Xia, D, He, L, Lv, X, Liao, X, et al.. COVID-19 in a patient with long-term use of glucocorticoids: a study of a familial cluster. J Clin Immunol 2020:108413.10.1016/j.clim.2020.108413Suche in Google Scholar PubMed PubMed Central
19. Kolifarhood, G, Aghaali, M, Saadati, HM, Taherpour, N, Rahimi, S, Izadi, N, et al.. Epidemiological and clinical aspects of COVID-19; a narrative review. Arch Acad Emerg Med 2020;8:e41. https://doi.org/10.22037/aaem.v8i1.620.Suche in Google Scholar
20. da Silva, JA. Convalescent plasma: a possible treatment of COVID-19 in India. Med J Armed Forces India 2020;76:236–7. https://doi.org/10.1016/j.mjafi.2020.04.006.Suche in Google Scholar PubMed PubMed Central
21. Dong, L, Hu, S, Gao, J. Discovering drugs to treat coronavirus disease 2019 (COVID-19). Drug Discov Ther 2020;14:58–60. https://doi.org/10.5582/ddt.2020.01012.Suche in Google Scholar PubMed
22. Sanders, JM, Monogue, ML, Jodlowski, TZ, Cutrell, JB. Pharmacologic treatments for coronavirus disease 2019 (COVID-19): a review. J Am Med Assoc 2020;323:1824–36https://doi.org/10.1001/jama.2020.6019.Suche in Google Scholar PubMed
23. Shen, C, Wang, Z, Zhao, F, Yang, Y, Li, J, Yuan, J, et al.. Treatment of 5 critically ill patients with COVID-19 with convalescent plasma. J Am Med Assoc 2020;323:1582–9https://doi.org/10.1001/jama.2020.6019.Suche in Google Scholar PubMed
24. Alam, M A, Quamri, MA, Sofi, G, Tarique, BM. Understanding hypothyroidism in Unani medicine. J Integr Med 2019;17:387–91. https://doi.org/10.1016/j.joim.2019.05.006.Suche in Google Scholar PubMed
25. Mason, RJ. Pathogenesis of COVID-19 from a cell biology perspective. Eur Respir J 2020:2000607.10.1183/13993003.00607-2020Suche in Google Scholar PubMed PubMed Central
26. Bhat, R, Hamid, A, Kunin, JR, Saboo, SS, Batra, K, Baruah, D, et al.. Chest imaging in patients hospitalized with COVID-19 infection-a case series. Curr Probl Diagn Radiol 2020;49:294–301https://doi.org/10.1067/j.cpradiol.2020.04.001.Suche in Google Scholar PubMed PubMed Central
27. Nicola, M, O’Neill, N, Sohrabi, C, Khan, M, Agha, M, Agha, R. Evidence based management guideline for the COVID-19 pandemic-review article. Int J Surg 2020;77:206–16https://doi.org/10.1016/j.ijsu.2020.04.001.Suche in Google Scholar PubMed PubMed Central
28. Mardani, R, Vasmehjani, AA, Zali, F, Gholami, A, Nasab, SD, Kaghazian, H, et al.. Laboratory parameters in detection of COVID-19 patients with positive RT-PCR; a diagnostic accuracy study. Arch Acad Emerg Med 2020;8:e43. eCollection 2020. https://doi.org/10.22037/aaem.v8i1.632.Suche in Google Scholar
29. Yang, P, Wang, X. COVID-19: a new challenge for human beings. Cell Mol Immunol 2020;17:555–7.10.1038/s41423-020-0407-xSuche in Google Scholar PubMed PubMed Central
30. Li, Y, Liu, X, Guo, L, Li, J, Zhong, D, Zhang, Y, et al.. Traditional Chinese herbal medicine for treating novel coronavirus (COVID-19) pneumonia: protocol for a systematic review and meta-analysis. Syst Rev 2020;9:75. https://doi.org/10.1186/s13643-020-01343-4.Suche in Google Scholar PubMed PubMed Central
31. Rastogi, S, Pandey, DN, Singh, RH. COVID-19 pandemic: a pragmatic plan for ayurveda intervention. J Ayurveda Integr Med 2020. https://doi.org/10.1016/j.jaim.2020.04.002 [Epub ahead of print].Suche in Google Scholar PubMed PubMed Central
32. Ang, L, Lee, HW, Kim, A, Lee, JA, Zhang, J, Lee, MS. Herbal medicine for treatment of children diagnosed with COVID-19: a review of guidelines. Compl Ther Clin Pract 2020;39:101174. https://doi.org/10.1016/j.ctcp.2020.101174.Suche in Google Scholar PubMed PubMed Central
33. Pascarella, G, Strumia, A, Piliego, C, Bruno, F, Del Buono, R, Costa, F, et al.. COVID‐19 diagnosis and management: a comprehensive review. J Intern Med 2020;288:192–206https://doi.org/10.1111/joim.13091.Suche in Google Scholar PubMed PubMed Central
34. Sina, I Al Qanoon fit Tib, Vol. 4. New Delhi: Idara Kitab Us Shifa, New Delhi, India; 2010.Suche in Google Scholar
35. Alam, MA, Quamri, MA. Herbal preparations in the management of hypothyroidism in Unani medicine. Drug Metab Pers Ther 2020. https://doi.org/10.1515/dmdi-2020-0123 [Epub ahead of print].Suche in Google Scholar PubMed
36. Samaqandi, AN. Sharah-e-Asbab wa Alamat (Urdu translation by Allama Hakeem Kabeeruddin). New Delhi: Aejaz Publishing House, India; 2007:499–516 pp.Suche in Google Scholar
37. Razi, AMIZ Kitab al Hawi, vol. 17. New Delhi: Central Council for Research in Unani Medicine New Delhi. Ministry of Health & Family Welfare, Govt. of India; 2008:9–36 pp.Suche in Google Scholar
38. Nikhat, S, Fazil, M. Overview of COVID-19; its prevention and management in the light of Unani medicine. Sci Total Environ 2020;728:138859. https://doi.org/10.1016/j.scitotenv.2020.138859.Suche in Google Scholar PubMed PubMed Central
39. Razi, AMBZ. Kitabul Mansoori (Urdu translation). New Delhi: Central Council for Research in Unani Medicine New Delhi. Ministry of Health & Family Welfare, Govt. of India; 1991:174–7 pp.Suche in Google Scholar
40. Gruner, OC. A Treatise on the Canon of Medicine of Avicenna. Incorporating a Translation of the First Book. New York: AMS Press; 1984.Suche in Google Scholar
41. Ghani, N. Khazianul Advia. New Delhi, India: IdaraKitab Us-Shifa; 2011.Suche in Google Scholar
42. Kabeeruddin, A, Biyaz-e-Kabeer. vol. I&II. Hyderabad Dakkan, India: Hikmat Depo; 1935.Suche in Google Scholar
43. Jadhav, P, Lal, H, Kshirsagar, N. Assessment of potency of PC-complexed Ocimum sanctum methanol extract in embryonated eggs against Influenza virus (H1N1). Phcog Mag 2014;10(1 Suppl):S86–9. https://doi.org/10.4103/0973-1296.127352.Suche in Google Scholar PubMed PubMed Central
44. Kumar, A, Agarwal, K, Maurya, AK, Shanker, K, Bushra, U, Tandon, S, et al.. Pharmacological and phytochemical evaluation of Ocimum sanctum root extracts for its anti-inflammatory, analgesic and antipyretic activities. Phcog Mag 2015;11:S217–24. https://doi.org/10.4103/0973-1296.157743.Suche in Google Scholar PubMed PubMed Central
45. Mondal, S, Varma, S, Bamola, VD, Naik, SN, Mirdha, BR, Padhi, MM, et al.. Double-blinded randomized controlled trial for immunomodulatory effects of Tulsi (Ocimum sanctum Linn.) leaf extract on healthy volunteers. J Ethnopharmacol 2011;136:452–6. https://doi.org/10.1016/j.jep.2011.05.012.Suche in Google Scholar PubMed
46. Ghoke, SS, Sood, R, Kumar, N, Pateriya, AK, Bhatia, S, Mishra, A, et al.. Evaluation of antiviral activity of Ocimum sanctum and Acacia arabica leaves extracts against H9N2 virus using embryonated chicken egg model. BMC Compl Alternative Med 2018;18:174. https://doi.org/10.1186/s12906-018-2238-1.Suche in Google Scholar PubMed PubMed Central
47. Elsayed, Y, Khan, NA. Immunity-boosting spices and the novel coronavirus. ACS Chem Neurosci 2020;11:1696–8. https://doi.org/10.1021/acschemneuro.0c00239.Suche in Google Scholar PubMed
48. Ulasli, M, Gurses, SA, Bayraktar, R, Yumrutas, O, Oztuzcu, S, Igci, M, et al.. The effects of Nigella sativa (Ns), Anthemishyalina (Ah) and Citrus sinensis (Cs) extracts on the replication of coronavirus and the expression of TRP genes family. Mol Biol Rep 2014;41:1703–11. https://doi.org/10.1007/s11033-014-3019-7.Suche in Google Scholar PubMed PubMed Central
49. Karimi, E, Oskoueian, E, Hendra, R, Jaafar, HZ. Evaluation of Crocus sativus L. stigma phenolic and flavonoid compounds and its antioxidant activity. Molecules 2010;15:6244–56. https://doi.org/10.3390/molecules15096244.Suche in Google Scholar PubMed PubMed Central
50. Leone, S, Recinella, L, Chiavaroli, A, Orlando, G, Ferrante, C, Leporini, L, et al.. Phytotherapic use of the Crocus sativus L. (Saffron) and its potential applications: a brief overview. Phytother Res 2018;32:2364–75. https://doi.org/10.1002/ptr.6181.Suche in Google Scholar PubMed
51. Jiang, ZY, Liu, WF, Zhang, XM, Luo, J, Ma, YB, Chen, JJ. Anti-HBV active constituents from Piper longum. Bioorg Med Chem Lett 2013;23:2123–7. https://doi.org/10.1016/j.bmcl.2013.01.118.Suche in Google Scholar PubMed
52. Kumar, S, Malhotra, S, K Prasad, A, V Van der Eycken, E, E Bracke, M, G Stetler-Stevenson, W, et al.. Anti-inflammatory and antioxidant properties of Piper species: a perspective from screening to molecular mechanisms. Curr Top Med Chem 2015;15:886–93. https://doi.org/10.2174/1568026615666150220120651.Suche in Google Scholar PubMed PubMed Central
53. San Chang, J, Wang, KC, Yeh, CF, Shieh, DE, Chiang, LC. Fresh ginger (Zingiber officinale) has anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines. J Ethnopharmacol 2013;145:146–51. https://doi.org/10.1016/j.jep.2012.10.043.Suche in Google Scholar PubMed
54. Danciu, C, Vlaia, L, Fetea, F, Hancianu, M, Coricovac, DE, Ciurlea, SA, et al.. Evaluation of phenolic profile, antioxidant and anticancer potential of two main representants of Zingiberaceae family against B164A5 murine melanoma cells. Biol Res 2015;48:1. https://doi.org/10.1186/0717-6287-48-1.Suche in Google Scholar PubMed PubMed Central
55. Fiore, C, Eisenhut, M, Krausse, R, Ragazzi, E, Pellati, D, Armanini, D, et al.. Antiviral effects of Glycyrrhiza species. Phytother Res 2008;22:141–8. https://doi.org/10.1002/ptr.2295.Suche in Google Scholar PubMed PubMed Central
56. Frattaruolo, L, Carullo, G, Brindisi, M, Mazzotta, S, Bellissimo, L, Rago, V, et al.. Antioxidant and anti-inflammatory activities of flavanones from Glycyrrhiza glabra L.(liquorice) leaf Phyto complexes: identification of licoflavanone as a modulator of NF-kB/MAPK pathway. Antioxidants 2019;8:186. https://doi.org/10.3390/antiox8060186.Suche in Google Scholar PubMed PubMed Central
57. Kalikar, MV, Thawani, VR, Varadpande, UK, Sontakke, SD, Singh, RP, Khiyani, RK. Immunomodulatory effect of Tinospora cordifolia extract in human immuno-deficiency virus positive patients. Indian J Pharmacol 2008;40:107–10. https://doi.org/10.4103/0253-7613.42302.Suche in Google Scholar PubMed PubMed Central
58. Alsuhaibani, S, Khan, MA. Immune-stimulatory and therapeutic activity of Tinospora cordifolia: double-edged sword against salmonellosis. J Immunol Res 2017; 2017.10.1155/2017/1787803Suche in Google Scholar
59. Bhat, SA, Rather, SA, Iqbal, A, Qureshi, HA, Islam, N. Immunomodulators for curtailing COVID-19: a positive approach. J Drug Deliv Therapeut 2020;10:286–94. https://doi.org/10.22270/jddt.v10i3-s.4085.Suche in Google Scholar
60. Verma, H, Patil, PR, Kolhapure, RM, Gopalkrishna, V. Antiviral activity of the Indian medicinal plant extract, Swertia chirata against herpes simplex viruses: a study by in-vitro and molecular approach. Indian J Med Microbiol 2008;26:322–6. https://doi.org/10.4103/0255-0857.43561.Suche in Google Scholar
61. Bhargava, S, Rao, PS, Bhargava, P, Shukla, S. Antipyretic potential of Swertia chirata Buch Ham. root extract. Sci Pharm 2009;77:617–24. https://doi.org/10.3797/scipharm.0812-10.Suche in Google Scholar
62. Lad, H, Bhatnagar, D. Amelioration of oxidative and inflammatory changes by Swertia chiraita leaves in experimental arthritis. Inflammopharmacology 2016;24:363–75. https://doi.org/10.1007/s10787-016-0290-3.Suche in Google Scholar
63. Available from: https://www.ayush.gov.in/docs/unani-guidelines.pdf. Guidelines for Unani Practitioners for COVID 19 [Accessed 24 Jul 2020].Suche in Google Scholar
64. Panyod, S, Ho, CT, Sheen, LY. Dietary therapy and herbal medicine for COVID-19 prevention: a review and perspective. J Tradit Complementary Med 2020;10:420–7. https://doi.org/10.1016/j.jtcme.2020.05.004.Suche in Google Scholar
65. Alam, MA, Quamri, MA, Ayman, U, Ansari, S, Ahad, M. Understanding Humma-e-Wabai (epidemic fever) and Amraz-e-Wabai (epidemic disease) in the light of Unani medicine. Drug Metab Pers Ther 2020. 2020–0124.R1. Accepted. https://doi.org/10.1515/dmdi-2020-0136 [Epub ahead of print].Suche in Google Scholar
66. Yang, Y. Use of herbal drugs to treat COVID-19 should be with caution. Lancet 2020;395:1689–90. https://doi.org/10.1016/S0140-6736(20)31143-0.Suche in Google Scholar
67. Ang, L, Song, E, Lee, HW, Lee, MS. Herbal medicine for the treatment of coronavirus disease 2019 (COVID-19): a systematic review and meta-analysis of randomized controlled trials. J Clin Med 2020;9:1583. https://doi.org/10.3390/jcm9051583.Suche in Google Scholar PubMed PubMed Central
68. Narkhede, RR, Pise, AV, Cheke, RS, Shinde, SD. Recognition of natural products as potential inhibitors of COVID-19 main protease (Mpro): in-silico evidences. Nat Prod Bioprospect 2020;10:297–306https://doi.org/10.1007/s13659-020-00253-1.Suche in Google Scholar PubMed PubMed Central
69. da Silva Antonio, A, Wiedemann, LS, Veiga-Junior, VF. Natural products’ role against COVID-19. RSC Adv 2020;10:23379–93. https://doi.org/10.1039/D0RA03514A.Suche in Google Scholar
70. Divya, M, Vijayakumar, S, Chen, J, Vaseeharan, B, Durán-Lara, EF. A review of South Indian medicinal plant has the ability to combat against deadly viruses along with COVID-19? Microb Pathog 2020:104277.10.1016/j.micpath.2020.104277Suche in Google Scholar PubMed PubMed Central
71. Majoosi, AIA. Kamilus Sanaa. (Urdu translation by Gulam Hasnain Kantoori), vol. 1&2. New Delhi: Idara Kitabus Shifa, India; 2010:620–1 pp. 428–30.Suche in Google Scholar
72. Kabeeruddin, HM. Hummiyat-e-Qanoon. Part-II. New Delhi: Central Council for Research in Unani Medicine New Delhi. Ministry of Health & Family Welfare, Govt. of India; 2009:39–47 pp.Suche in Google Scholar
73. Alam, MA, Quamri, MA, Sofi, G, Ayman, U, Ansari, S, Ahad, M. Understanding coronavirus disease (COVID-19) in the light of epidemic disease described in Unani medicine. Drug Metab Pers Ther 2020. https://doi.org/10.1515/dmdi-2020-0136 [Epub ahead of print].Suche in Google Scholar PubMed
© 2020 Walter de Gruyter GmbH, Berlin/Boston
Artikel in diesem Heft
- Frontmatter
- Mini Reviews
- Home environmental interventions for prevention of respiratory tract infections: a systematic review and meta-analysis
- Water and wastewater as potential sources of SARS-CoV-2 transmission: a systematic review
- Review Articles
- The role of sensory and olfactory pathways in multiple chemical sensitivity
- Temporal assessment of municipal solid waste management in Nigeria: prospects for circular economy adoption
- Knowledge, attitude, practice and clinical recommendations of health care workers towards COVID-19: a systematic review
- Drinking water heavy metal toxicity and chronic kidney diseases: a systematic review
- A systematic review report on tobacco products and its health issues in India
- Possible role of Unani Pharmacology in COVID-19 – a narrative review
- The indicators and methods used for measuring urban liveability: a scoping review
- Complementary and alternative medicine therapies and COVID-19: a systematic review
Artikel in diesem Heft
- Frontmatter
- Mini Reviews
- Home environmental interventions for prevention of respiratory tract infections: a systematic review and meta-analysis
- Water and wastewater as potential sources of SARS-CoV-2 transmission: a systematic review
- Review Articles
- The role of sensory and olfactory pathways in multiple chemical sensitivity
- Temporal assessment of municipal solid waste management in Nigeria: prospects for circular economy adoption
- Knowledge, attitude, practice and clinical recommendations of health care workers towards COVID-19: a systematic review
- Drinking water heavy metal toxicity and chronic kidney diseases: a systematic review
- A systematic review report on tobacco products and its health issues in India
- Possible role of Unani Pharmacology in COVID-19 – a narrative review
- The indicators and methods used for measuring urban liveability: a scoping review
- Complementary and alternative medicine therapies and COVID-19: a systematic review