Benzene absorption in animals and man: an overview
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Jurij J. Hostynek
Abstract
Benzene is a widespread, naturally occurring substance of environmental concern as systemic exposure in humans is proven to be carcinogenic. Dermal exposure is a common and significant route of systemic entry and percutaneous absorption is critical in exposure risk assessment. This article reviews the scientific principles, methodologies, and research behind the multiple steps of the percutaneous absorption of benzene in animals and man and the application of this information to optimize exposure risk assessments. A focus on occupational exposures to benzene is made with an exploration of the limitations of current preventative measures and hazard assessments. Finally, recommendations for future research to fill existing knowledge gaps are made.
©2012 by Walter de Gruyter Berlin Boston
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Artikel in diesem Heft
- Masthead
- Masthead
- Editorial
- New Leadership for Reviews on Environmental Health
- Original Article
- Comparison of pollution levels on the Mississippi Gulf Coast during the 2010 Gulf BP oil spill to ecological and health-based standards
- Review Articles
- Can nutrition lessen the effects of secondhand smoke exposure among children?
- Benzene absorption in animals and man: an overview
- Persistent polar depletion of stratospheric ozone and emergent mechanisms of ultraviolet radiation-mediated health dysregulation
- Misregulated inflammation as an outcome of early-life exposure to endocrine-disrupting chemicals
- Effect of particulate matter air pollution on C-reactive protein: a review of epidemiologic studies
